Results 131 to 140 of about 314,046 (312)

Prevalence of cardiac dysfunction and longitudinal changes in cardiac function after breast cancer treatment with chemotherapy with/without radiation therapy compared with controls

Breast
Introduction: Breast cancer survivors are known to have a higher prevalence of mild systolic cardiac dysfunction compared to the general population, due to the effects of chemotherapy with/without radiation therapy.
L.T. van der Wal, S.W.M.C. Maass, M.R. de Boer, M.H. Blanker, A.P.G. Crijns, J.A. Gietema, P. van der Meer, G.H. de Bock, D. Brandenbarg   +8 more
doaj   +1 more source

Left ventricular dysfunction in the newborn

Translational Pediatrics, 2023
Menahem, Samuel, Sehgal, Arvind
openaire   +2 more sources

The Content of Vasodilation Factors in Blood Serum at Different Levels of Systolic- Diastolic Dysfunction of Left Ventricular with Stable Stenocardia Complicated by Heart Failure

, 2017
Introduction. Congestive heart failure (CHF) is still the most topical medical­and­social problem all around the world. It is the most common and life­threatening disease of the cardiovascular system, resulting in permanent disability, leads to permanent
Muzyka N., Denesyuk V.
core   +1 more source

Biomimetic Bone Marrow Monocyte Membrane‐Fused Extracellular Vesicles for Targeted Therapy of Myocardial Infarction

Advanced Science, EarlyView.
This study develops a biomimetic delivery system (M‐hEV) by fusing monocyte membranes with extracellular vesicles for targeted therapy of damaged cardiac tissue. The system homes to injured myocardium through specific molecular pathways. In a myocardial infarction model, M‐hEV effectively accumulates in the heart, reduces infarct size, alleviates ...
Jiaxin Song, Hao Yang, Qiqi Zhang, Wenqin Zhou, Rui Wang, Yuxing Xie, Emeli Chatterjee, Guoping Li, Jizong Jiang, Qiulian Zhou, Cuimei Zhao   +10 more
wiley   +1 more source

Depressive Symptoms and Left Ventricular Diastolic Dysfunction Among Men and Women with HIV [PDF]

Background and Aim: The prevalence of depressive symptoms and major depressive disorder is high among adults living with HIV. Depressive symptoms are associated with increased cardiovascular disease risk.
Alcaide, Maria L., Margaret A. Fischl, Jones, Deborah L., Adaora A. Adimora, Spence, Amanda Blair, Rodriguez, Violeta J, McKay, Heather, Joao A. C. Lima, Carlos J. Rodriguez, Wingood, Gina, Weinstein, Andrea M., Post, Wendy S., Martinez, Claudia, Kizer, Jorge R, Fischl, Margaret A., Wendy S. Post, Kozlova, Sofia, Violeta J. Rodriguez, Lima, Joao AC, Post, Wendy S, Katherine C. Wu, Rodriguez, Violeta J., Amanda Blair Spence, Jones, Deborah L, Konkle-Parker, Deborah, Yasmeen Golzar, Wu, Katherine C., Lima, Joao A. C., Haw, Nel Jason, Wise, Jenni M., Lazar, Jason, Jason Lazar, Wise, Jenni M, Wu, Katherine C, Fischl, Margaret A, Budoff, Matthew, Gina Wingood, Golzar, Yasmeen, Frank J Palella, Alcaide, Maria L, Sofia Kozlova, Plankey, Michael, Rodriguez, Carlos J, Claudia Martinez, Jorge R. Kizer, Michael Plankey, Deborah L. Jones, Maria L. Alcaide, Rodriguez, Carlos J., Deborah Konkle-Parker, Adimora, Adaora A, Palella, Frank J, Nel Jason Haw, Andrea M. Weinstein, Jenni M. Wise, Matthew Budoff, Heather McKay, Weinstein, Andrea M, Kizer, Jorge R., Adimora, Adaora A.   +59 more
core   +1 more source

CK2α Deficiency Drives Myocardial Fibrosis via Desmin‐Induced Mitochondrial Dysfunction

Advanced Science, EarlyView.
CK2α preserves mitochondrial homeostasis by phosphorylating Desmin to recruit Cryab, ensuring proper filament assembly. CK2α deficiency disrupts this interaction, causing mitochondrial dysfunction, metabolic shifts, bioenergetic failure, and oxidative stress—ultimately establishing a pro‐fibrotic environment that drives cardiac fibrosis.
Canjie Ma, Jiali Jia, Juncong Lan, Jing Wang, Dan Rao, Lanlan Rao, Weibin Zhang, Dongpeng Wu, Jie Zhang, Gang Wang, Baohua Liu, Ying Ao, Zimei Wang   +12 more
wiley   +1 more source

Brown Adipocyte Sheets Alleviate Myocardial Ischemia–Reperfusion Injury Through NRG4–ErbB4–Dependent Ferroptosis Inhibition

Advanced Science, EarlyView.
Brown adipocyte sheets are engineered to protect the heart against myocardial ischemia–reperfusion injury by restraining ferroptosis. Upon transplantation onto the cardiac surface, they improve cardiac function, limit infarction and fibrosis, and enhance angiogenesis.
Lifu Sun, Yuting Liu, Jingbo Zhang, Takuji Kawamura, Junjun Li, Li Liu, Shigeru Miyagawa   +6 more
wiley   +1 more source

Prevalence and predictors of left ventricular dysfunction among patients with chronic kidney disease attending Muhimbili National Hospital in Tanzania — a cross-sectional study

, 2018
Pilly Chillo, Eva Mujuni Department of Internal Medicine, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania Purpose: Chronic kidney disease (CKD) is prevalent in sub-Saharan Africa and is a significant cause of mortality, which ...
Chillo P, Mujuni E
core  

Value of primary care electrocardiography for the prediction of left ventricular systolic dysfunction in patients with suspected heart failure

, 2006
To compare electrocardiogram (ECG) with measurement of N-terminal pro-B-type natriuretic peptides (NTproBNP) as the General Practitioner's (GP) initial test for suspected heart failure patients from the community.
Senior, R., Lim, T. K., Collinson, P.O., Gaze, D.C., Celik, E.   +4 more
core   +1 more source

Leonurine Ameliorates Doxorubicin‐Induced Cardiotoxicity via STING/NF‐κB/NLRP3 Inflammasome Signaling Pathway

Advanced Science, EarlyView.
ABSTRACT Doxorubicin‐induced cardiomyopathy (DIC) remains a dose‐limiting clinical challenge. This study reveals that cardiac vascular endothelial cells (CVECs) act as initial sensors of doxorubicin cardiotoxicity: circulating doxorubicin activates the cGAS‑STING pathway in CVECs, triggering NLRP3 inflammasome‑mediated pyroptosis and release of ...
Wang Jun, Chen Xiaoyang, Xu Jianglin, Yang Zhi, Tao Meijiao, He Jiale, Zhao Jiangfeng, Hei Xuanding, Xu Xuegong, Wang Wei, Li Chun   +10 more
wiley   +1 more source