Results 271 to 280 of about 1,029,529 (375)

Does Gastrointestinal Bleeding Increase the Risk of Thromboembolic Events in Patients Supported With CF‐LVADs?

open access: yesArtificial Organs, EarlyView.
Gastrointestinal bleeding significantly increases thromboembolic risk. Higher risk was also seen in patients aged ≥ 50 years, Black patients, and those with older CF‐LVAD models. ABSTRACT Background Gastrointestinal bleeding is a common complication in continuous‐flow left ventricular assist device (CF‐LVAD) patients. Managing gastrointestinal bleeding
Anh Nguyen   +6 more
wiley   +1 more source

Accelerated Ischemic Disease Presenting as Ventricular Fibrillation. [PDF]

open access: yesJ Community Hosp Intern Med Perspect
Javed N   +4 more
europepmc   +1 more source

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen   +3 more
wiley   +1 more source

The anti‐fibrotic effects of novel heart failure pharmacotherapies in advanced heart failure patients

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Novel heart failure (HF) pharmacotherapies, including angiotensin receptor‐neprilysin inhibitor (ARNI) and sodium‐glucose cotransporter 2 inhibitors (SGLT2is), may confer cardiovascular benefits by attenuating myocardial fibrosis. However, direct evidence from human failing myocardial samples is limited.
Dávid Nagy   +10 more
wiley   +1 more source

Mitochondrial Ca2+ overload is a pivotal risk factor for lethal ventricular arrhythmias due to the oxidation of mitochondrial respirasome and energetic failure

open access: yesBritish Journal of Pharmacology, EarlyView.
The data that support the findings of this study are available from the corresponding author upon reasonable request. Some data may not be made available because of privacy or ethical restrictions. Background and Purpose Ventricular arrhythmias are a leading cause of death among patients with cardiovascular diseases and are associated with elevated ...
Felipe de Jesús Salazar‐Ramírez   +13 more
wiley   +1 more source

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