Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos +2 more
wiley +1 more source
Immunosuppressive Drug Use in Limited Systemic Sclerosis: An International Survey
Objective Current guidelines recommend immunosuppressive treatment for diffuse cutaneous systemic sclerosis but are less clear on their use in limited cutaneous systemic sclerosis (lcSSc) in the absence of internal organ complications. We conducted an international survey to understand current immunosuppressive drug prescribing patterns in lcSSc ...
Sabrina Hoa +3 more
wiley +1 more source
113 healthy subjects with normal blood pressure and 26 patients with essential hypertension (BP 140-159/90-99 mm Hg) were inspected by echocardiography. All subjects were divided into 5 groups according to the blood pressure (BP) level.
A. V. Tuyev, Y. B. Hovayeva
doaj
Comparative evaluation of left ventricular mass regression after aortic valve replacement: a prospective randomized analysis [PDF]
Background: We assessed the hemodynamic performance of various prostheses and the clinical outcomes after aortic valve replacement, in different age groups.
Wood Jeffrey P +11 more
core +2 more sources
The Gut–Heart Axis in Systemic Sclerosis: Evidence From a Large Prospective Early Disease Cohort
Objective Cardiac involvement significantly impacts prognosis in systemic sclerosis (SSc), highlighting the need for early risk stratification. Gastrointestinal (GI) symptoms are common and often manifest early. Emerging data suggest a link between GI and cardiac manifestations, possibly through shared mechanisms like dysautonomia.
Francesca R. Di Ciommo +9 more
wiley +1 more source
INAPPROPRIATE LEFT VENTRICULAR MASS, IN CHILDREN WITH PREDYALITIC CHRONIC RENAL INSUFFICIENCY [PDF]
Background: Increased left ventricular (LV) mass in children with chronic renal insufficiency (CRI) might represent an adaptive mechanism to compensate for increased workload.
Romano, Carmela
core +1 more source
Left ventricular diastolic dysfunction: identifying presence by left atrial function
Objective: The left atrium (LA) is exposed to left ventricular pressure during diastole. Applying the 2016 American Society of Echocardiography left ventricular diastolic function (LVDF) guidelines, this study aims to investigate whether left atrial ...
Emily Worley +3 more
doaj +1 more source
Analysis of left ventricular function, left ventricular outflow tract and aortic valve area using computed tomography: Influence of reconstruction parameters on measurement accuracy. [PDF]
Hell MM +5 more
europepmc +1 more source
Electrocardiographic (ECG) criteria for determining left ventricular mass in young healthy men; data from the LARGE Heart study [PDF]
Background: Doubts remain over the use of the ECG in identifying those with increased left ventricular (LV) mass. This is especially so in young individuals, despite their high prevalence of ECG criteria for LV hypertrophy.
Syed Sohaib +12 more
core +1 more source
Distinct Systemic Sclerosis Phenotypes Related to Ethnicity: An Opportunity to Personalize Care?
Objective The objective is to describe and compare demographic, clinical, and serological characteristics of patients with systemic sclerosis (SSc) according to ethnic background. Methods Participants enrolled in the Canadian Scleroderma Research Group cohort who self‐identified to a single ethnicity group were included.
Danick Goulet +11 more
wiley +1 more source

