Results 141 to 150 of about 781,920 (336)

Pretransplant pulmonary hypertension and long-term allograft right ventricular function [PDF]

open access: yes, 2017
Background: Graft right ventricular (RV) function is compromised directly posttransplant, especially in heart transplantation (HTx) recipients with pretransplant pulmonary hypertension (PH).
Carrel, Thierry   +7 more
core  

PFKM‐Driven Lactate Overproduction Promotes Atrial Fibrillation via Triggering Cardiac Fibroblasts Histone Lactylation

open access: yesAdvanced Science, EarlyView.
The upregulation of PFKM activates glycolysis, thereby enhancing lactate production in atrial tissue. Atrial lactate accumulation promotes global lactylation and H3K18 lactylation in atrial fibroblasts. P300‐mediated H3K18 lactylation up‐regulates TGF‐β1 transcription, leading to fibroblast activation and thereby contributing to atrial fibrosis.
Ning Fang   +15 more
wiley   +1 more source

The Impact of Myocardial Infarction on Ventricular Function [PDF]

open access: yes, 1990
Eighty one patients were studied using radionuclide ventriculography to study the effects of myocardial infarction (36 anterior and 45 inferior) on ventricular function during the early and convalescent phases.
McGhie, Arthur Iain
core  

Gut Metabolite Indole‐3‐Propionic Acid Regulates Macrophage Autophagy Through PPT1 Inhibiting Aging‐Related Myocardial Fibrosis

open access: yesAdvanced Science, EarlyView.
IPA is an intestinal tryptophan metabolite whose effects decline with decreased heart function. Supplementing IPA can alleviate the aging‐related myocardial fibrosis through PPT1. PPT1 is a key protein localized to lysosomes, and IPA can restore macrophage autophagy function by regulating PPT1 expresssions, thereby reducing aging‐related myocardial ...
Jing Lu   +16 more
wiley   +1 more source

Modified Nikaidoh procedure for the correction of complex forms of transposition of the great arteries with ventricular septal defect and left ventricular outflow tract obstruction: mid-term results [PDF]

open access: yes, 2017
OBJECTIVES Different surgical techniques for the treatment of complex transposition of the great arteries (TGA) with ventricular septal defect and left ventricular outflow tract obstruction (LVOTO) have been developed, in particular the Rastelli ...
Berger, Felix   +4 more
core  

Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine

open access: yesAdvanced Science, EarlyView.
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang   +4 more
wiley   +1 more source

Biventricular Myocardial Noncompaction [PDF]

open access: yes, 2006
The isolated noncompacted ventricular myocardium (NCVM), characterized by excessively prominent trabecular meshwork and deep intertrabecular recesses, is seen in the early period of embryogenesis.
Nizamettin Toprak   +2 more
core  

Ligilactobacillus Murinus and Lactobacillus Johnsonii Suppress Macrophage Pyroptosis in Atherosclerosis through Butyrate‐GPR109A‐GSDMD Axis

open access: yesAdvanced Science, EarlyView.
Oral aspirin administration induces intestinal expansion of Lactobacillus murinus and Lactobacillus johnsonii, which suppresses the progression of atherosclerosis. This microbial expansion significantly enhances butyrate production by providing lactate as a metabolic substrate, thereby fostering the growth of butyrate‐producing bacteria. Butyrate plays
Rui Hua   +15 more
wiley   +1 more source

Acute Effects of Hemodialysis on Left and Right Ventricular Function: A Doppler Tissue Imaging Study

open access: yesÇukurova Üniversitesi Tıp Fakültesi Dergisi, 2012
Purpose: Doppler tissue imaging (DTI) allows noninvasive assessment of both left ventricular (LV) and right ventricular (RV) function. The aim of this study was to evaluate the effect of hemodialysis (HD) on LV and RV function using DTI.
Tansel Erol   +9 more
doaj  

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