Results 171 to 180 of about 781,920 (336)

In Vivo Dynamic Coronary Arteries Blood Flow Imaging Based on Multi‐Cycle Phase Clustering Ultrafast Ultrasound

Advanced Science, EarlyView.
This study addresses a critical gap in ultrafast ultrasound cardiovascular flow imaging and introduces a transformative approach, Clustering Singular Value Decomposition (cSVD), which enables dynamic cardiovascular flow imaging throughout full cardiac cycle without motion correction and hyper‐fast imaging strategies.
Hao Yu, Jiabin Zhang, Feng Feng, Jinyu Yang, Yu Xia, Yunlong Zhao, Jue Zhang   +6 more
wiley   +1 more source

Anti‐Icing Organogel Enables Quasi‐Homogeneous Supercooling Preservation of Mouse Hearts

Advanced Science, EarlyView.
An organogel interface with a large energy barrier for ice nucleation is proposed to enable a quasi‐homogeneous supercooling preservation for organs. This method does not rely on cryoprotectant agents or machine perfusion and can double the ex vivo storage time of mouse hearts.
Junhao Li, Wei Wang, Chenghao Li, Lintao Kuang, Zhi Huang, Xing Chen, Zhenghao Guo, Kang Liu, Jinping Liu   +8 more
wiley   +1 more source

Right ventricular systolic function in hypertensive heart failure

Vascular Health and Risk Management, 2017
OA Oketona,1 MO Balogun,2 AO Akintomide,2 OE Ajayi,2 RA Adebayo,2 TO Mene-Afejuku,3 OT Oketona,1 OJ Bamikole2 1Fort Nelson General Hospital, Fort Nelson, BC, Canada; 2Cardiology Unit, Department of Medicine, Obafemi Awolowo University Teaching Hospitals ...
Oketona OA, Balogun MO, Akintomide AO, Ajayi OE, Adebayo RA, Mene-Afejuku TO, Oketona OT, Bamikole OJ   +7 more
doaj  

Prognostic incremental role of right ventricular function in acute decompensation of advanced chronic heart failure

European Journal of Heart Failure, 2016
S. Frea, S. Pidello, V. Bovolo, C. Iacovino, E. Franco, F. Pinneri, A. Galluzzo, A. Volpe, M. Visconti, Andrea Peirone, M. Morello, S. Bergerone, F. Gaita   +12 more
semanticscholar   +1 more source

Rapamycin Alleviates Heart Failure Caused by Mitochondrial Dysfunction and SERCA Hypoactivity in Syntaxin 12/13 Deficient Models

Advanced Science, EarlyView.
Rapamycin alleviates heart failure via TFEB and CaMKII pathways in Syntaxin 12/13 deficient models. Stx12 deficiency causes heart failure via impaired iron trafficking to mitochondria, reducing respiratory complexes and sarcoplasmic reticulum Ca2+‐ATPase (SERCA).
Run‐Zhou Yang, Fang Li, Jiao Liu, Shu‐Ang Li, Dan‐Hua Liu, Zhuanbin Wu, Pei‐Pei Liu, Wenju Liu, Bin Zhou, Cizhong Jiang, Haibing Zhang, Ying Yu, Jian‐Sheng Kang   +12 more
wiley   +1 more source

ALKBH5‐Mediated M6A Demethylation of G3BP1 Attenuates Ferroptosis Via Cytoplasmic Retention of YBX1/p53 in Diabetic Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
ALKBH5 promoted G3BP1 expression via m⁶A methylation at sites 142/173. G3BP1 interacts with YBX1 and p53, reducing their nuclear translocation and decreasing p53‐mediated SLC7A11 repression. This inhibites cardiomyocyte ferroptosis and mitigates myocardial damage during diabetic ischemia‐reperfusion injury.
Wenyuan Li, Wei Li, Yan Leng, Heng Xu, Zhongyuan Xia, Yao Wang   +5 more
wiley   +1 more source

Interleukin-6 is independently associated with right ventricular function in pulmonary arterial hypertension.

The Journal of Heart and Lung Transplantation, 2017
K. Prins, Stephen L. Archer, M. Pritzker, Lauren Rose, E. Weir, A. Sharma, T. Thenappan   +6 more
semanticscholar   +1 more source

Atrial Fibroblasts‐Derived Extracellular Vesicles Exacerbate Atrial Arrhythmogenesis

Advanced Science, EarlyView.
Exosome miR‐224‐5p derived from angiotensin II‐treated atrial fibroblasts creates a substrate for AF by promoting atrial electrical remodeling. Increased exosome miR‐224‐5p enhances AF susceptibility by inhibiting CACNA1c expression and decreasing ICa current of atrial cardiomyocytes.
Yue Yuan, Xinbo Zhao, Xuejie Han, Yukai Cao, Xuexin Jin, Ling Shi, Xin Bi, Desheng Li, Yun Zhang, Wenbo Ma, Jiahui Song, Zhenwei Pan, Zhiren Zhang, Yue Li   +13 more
wiley   +1 more source

FOXM1 Protects Against Myocardial Ischemia‐Reperfusion Injury in Rodent and Porcine Models by Suppressing MKRN1‐Dependent LKB1 Ubiquitination

Advanced Science, EarlyView.
FOXM1 maintains mitochondrial bioenergetic function by inhibiting MKRN1‐mediated ubiquitination of LKB1 in cardiomyocytes. Loss of FOXM1 in cardiomyocytes results in upregulation of MKRN1, which enhances LKB1 ubiquitination and disrupts AMPK signaling and energy metabolism pathways. Conversely, FOXM1 overexpression preserves mitochondrial bioenergetics
Shuai Song, Xiaokai Zhang, Zihang Huang, Zhiqiang Pei, Linqi Zeng, Fengze Cai, Tongyao Wang, Mohan Li, Chenyan Liu, Yining Song, Jiahao Guo, Hao Lu, Xinyu Weng, Li Shen, Xiaochun Zhang, Xingxing Cai, Aijun Sun, Junbo Ge   +17 more
wiley   +1 more source

Imaging right ventricular function to predict outcome in pulmonary arterial hypertension.

International Journal of Cardiology, 2016
M. Brewis, A. Bellofiore, R. Vanderpool, N. Chesler, Martin Johnson, R. Naeije, A. Peacock   +6 more
semanticscholar   +1 more source