Results 171 to 180 of about 683,914 (333)
Working model of Adss1‐mediated regulation of energy metabolism in adipose tissue. In beige adipocytes, Adss1 interacts with HDAC3 in the cytoplasm, and its loss reduces nuclear HDAC3 while increasing cytosolic fractions. This redistribution suppresses HDAC activity and enhances H3K27 acetylation at the Gk promoter, leading to transcriptional ...
Jingjing Sun +16 more
wiley +1 more source
FMO2 Promotes Angiogenesis via Regulation of N‐Acetylornithine
This study identifies flavin‐containing monooxygenase 2 (FMO2) as a novel proangiogenic regulator in endothelial cells. Targeted FMO2 ablation impairs vessel sprouting, whereas its compensation potently enhances angiogenesis. Metabolomics and single‐cell sequencing reveal that FMO2 drives vascular growth via the N‐acetylornithine/ATF3/NOTCH1 axis ...
Jingyi Wang +15 more
wiley +1 more source
Heart failure with preserved left ventricular systolic function: a hospital cohort study [PDF]
Colin Berry +5 more
openalex +1 more source
Effects of Obesity and Diabesity on Ventricular Muscle Structure and Function in the Zucker Rat [PDF]
Ahmed Sultan +5 more
openalex +1 more source
This study presents an engineered human interferon‐lambda (hIFN‐λ) as an intranasal prophylactic against respiratory viruses. By combining AI‐guided backbone redesign and glycoengineering, the authors developed a thermostable, protease‐resistant, and scalable variant with improved mucosal penetration.
Jeongwon Yun +12 more
wiley +1 more source
Surveillance of left ventricular function among cancer survivors. [PDF]
Soh CH, Marwick TH.
europepmc +1 more source
Vitamin D (VitD) modulates olfactory function by remodeling dendrodendritic synapses in tufted cells through vitamin D receptor‐dependent transcriptional and translational mechanisms. VitD regulates synaptic protein translation partially via mTOR signaling.
Pengcheng Ren +9 more
wiley +1 more source
Mild carbon monoxide poisoning impairs left ventricular diastolic function
Özgür Çiftçi +6 more
openalex +1 more source

