Results 221 to 230 of about 6,056,841 (295)

An echocardiographic study of right ventricular function and pulmonary systolic pressure in patients treated with anthracyclines. [PDF]

open access: yesJ Cardiovasc Imaging
Ozan R   +10 more
europepmc   +1 more source

Stroke‐Heart Syndrome: Mechanisms, Temporal Phenotypes, and Diagnostic Reasoning

open access: yesAdvanced Science, EarlyView.
Stroke‐heart syndrome describes new or worsened cardiac abnormalities after acute stroke. This Review defines its clinical boundaries, traces autonomic, inflammatory, endothelial, and supply‐demand mechanisms across time, and proposes provisional phenotypes that integrate lesion location, premorbid cardiac substrate, serial biomarkers ...
Fa Lin   +13 more
wiley   +1 more source

A UBE3A‐UTX Proteostasis‐Epigenetic Axis Governs Hypothalamic Energy Homeostasis

open access: yesAdvanced Science, EarlyView.
Ubiquitin protein ligase E3A (UBE3A) regulates hypothalamic energy homeostasis and promotes degradation of the histone demethylase UTX (KDM6A). Neuronal UBE3A loss increases susceptibility to diet‐induced obesity and is accompanied by UTX accumulation, reduced histone H3 lysine 27 trimethylation, and altered endoplasmic reticulum stress‐responsive gene
Junekyoung Lee   +7 more
wiley   +1 more source

A Single Volatile VO2 Memristor Enabling Neuromorphic Perception, Learning, and Computing

open access: yesAdvanced Electronic Materials, EarlyView.
A single volatile VO2 memristor fabricated via atomic layer deposition is demonstrated as a multifunctional neuromorphic device enabled by intrinsic threshold‐switching dynamics. The device reproduces neuron‐like integration and firing, short‐timescale associative learning, temporal ECG pattern classification, and nociceptive responses to electrical ...
Bingkai Ding   +7 more
wiley   +1 more source

Chinese Expert Consensus on the Clinical Application of Finerenone in Geriatric Comorbidities

open access: yesAGING MEDICINE, EarlyView.
Mineralocorticoid receptor (MR) overactivation drives inflammation, oxidative stress, and fibrosis in the heart, kidneys, and vasculature, leading to cardiorenal dysfunction. MR signaling promotes hypertrophy, remodeling, and injury through pathways like oxidative stress and inflammation, resulting in vascular stiffness and progressive organ damage ...
Xiaoming Wang, Cuntai Zhang
wiley   +1 more source

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