Results 131 to 140 of about 13,694 (255)

Antitachycardia Pacing for Fast Scar-Mediated Ventricular Tachycardia Across Non-Ischemic Cardiomyopathies: A Case Series. [PDF]

Int Med Case Rep J
Karakasis P, Stavropoulos G, Efthimiadis GK, Karamitsos T, Fragakis N.   +4 more
europepmc   +1 more source

Genome‐wide network analysis identifies the lncRNA‐92467/miR‐205‐5p/PTPRM/CAMs axis in a rat model of hypoxic pulmonary hypertension

Animal Models and Experimental Medicine, EarlyView.
The pathogenesis of hypoxic pulmonary hypertension (HPH) remains unclear. In this study, we explored its key regulatory mechanisms using animal models, RNA sequencing, and cellular assays. We found that lncRNA‐92467 functions as a ceRNA, binding miR‐205‐5p, and thereby upregulating PTPRM, inhibiting abnormal proliferation and migration of endothelial ...
Yan‐Ying Shen, Yi‐Bing Chen, Xin Li, Xiang Xu, Ge Guo, Han‐Lu Li, Yong‐Ming Yao, Chun‐Lei Liu   +7 more
wiley   +1 more source

Advantages of the QDOT MICRO Catheter in Finding Conduction Gaps in Pulmonary Vein Isolation Compared With the Conventional 3.5-mm Tip Electrode. [PDF]

J Cardiovasc Electrophysiol
Masuda K, Nagahara D, Hatano R, Nishizaki K, Yuda S.   +4 more
europepmc   +1 more source

The diagnostic value of the circadian rhythm gene KLF10 in anxiety‐depressive disorders and its neuroimmune regulatory mechanisms

Animal Models and Experimental Medicine, EarlyView.
This graphical abstract illustrates the protective role and molecular mechanism of the circadian rhythm‐related gene KLF10, identified as a diagnostic biomarker and therapeutic target in anxiety‐depressive disorder. Model establishment and phenotypes: An anxiety‐depression model was successfully established by chronic restraint stress combined with ...
Anlan Liu, Weifeng Guo, Jianxiang Li, Tiange Zhang, Dan Xu   +4 more
wiley   +1 more source

Functional Substrate Mapping in Ablation for Scar-Related Ventricular Tachycardia. [PDF]

Rev Cardiovasc Med
Nakahara S, Sato H, Bradfield JS.
europepmc   +1 more source

A rhesus macaque model of α‐dystroglycanopathy caused by a POMT1 splice altering variant

Animal Models and Experimental Medicine, EarlyView.
Rhesus macaques homozygous for a naturally occurring spice altering variant in the POMT1 gene develop lissencephaly, microphthalmia, and muscular contracture. The presentation models severe presentation of the human Walker‐Warburg syndrome. Abstract Background Biallelic mutations in genes associated with α‐dystroglycan glycosylation manifest in a ...
Anya Nordlund, Brian LaMendola, Nathan P. Crilly, Seth Kittle, Betsy M. Ferguson, Anne D. Lewis, Jeff Wall, Samuel M. Peterson   +7 more
wiley   +1 more source

Baseline podocyte‐associated state and persistent cell–matrix transcriptional programs are associated with BALB/c substrain differences in adriamycin nephropathy

Animal Models and Experimental Medicine, EarlyView.
Two closely related BALB/c substrains exhibit different early responses to adriamycin (ADR)‐induced nephropathy. BALB/cByJcl mice showed lower baseline WT1‐positive nuclei counts and NPHS1 immunoreactivity than BALB/cAJcl mice, together with extracellular matrix and integrin programs that were enriched at baseline and persisted at Day 5.
Ryuya Nakagawa, Masaki Watanabe, Koyuki Kawamoto, Momoka Hiratsuka, Takeru Sasaki, Nobuya Sasaki   +5 more
wiley   +1 more source

Long-Term Heart Failure Stabilization and Autonomic Trends After Bilateral Cardiac Sympathetic Denervation. [PDF]

JACC Case Rep
Miki Y, Yoshimura S, Sasaki T, Kaseno K, Nakamura K, Niwamae N, Kamiyoshihara M, Naito S.   +7 more
europepmc   +1 more source

Adenosine monophosphate–activated protein kinase activation is associated with suppression of NLRP3 inflammasome–mediated neuroinflammation in a weight‐drop model of traumatic brain injury in Sprague–Dawley rats

Animal Models and Experimental Medicine, EarlyView.
This graphical abstract illustrates the study's schematic model. Adenosine monophosphate–activated protein kinase (AMPK) activators exhibited neuroprotection in the weight‐drop model of traumatic brain injury by improving cognition and regulating oxidative stress, microglial activation, and nucleotide‐binding oligomerization domain, leucine‐rich repeat,
Triveni Kodi, Paka Sravan Kumar, Krishnadas Nandakumar, Anoop Kishore   +3 more
wiley   +1 more source

Dissociated Purkinje potential as an active driver of multifocal Purkinje ventricular tachycardia: A case report. [PDF]

HeartRhythm Case Rep
Hayashi Y, Wakasa S, Hirayama S, Fukuda K, Yanagishita T, Fukuda D.   +5 more
europepmc   +1 more source