Results 211 to 220 of about 553,316 (296)

Case Report: Discordant hypertrophic cardiomyopathy in monozygotic twins with LEOPARD syndrome and an identical PTPN11 c.1391G > C (p.Gly464Ala) mutation. [PDF]

Front Cardiovasc Med
Xue X, Ning Y, Yao F, Zhang X, Song X.
europepmc   +1 more source

Multiple left ventricular outflow obstructions

The Journal of Thoracic and Cardiovascular Surgery, 1972
Richard E. Kerber, Richard A. Greene, Lawrence H. Cohn, Lewis Wexler, Joseph P. Kriss, Donald C. Harrison   +5 more
openaire   +1 more source

Methyl 4‐O‐Demethylbarbatate Destabilises HIF‐1α and Enhances Temozolomide Sensitivity in Glioma Cells

Cell Proliferation, EarlyView.
The lichen‐derived metabolite methyl 4‐O‐demethylbarbatate (Me‐4‐O‐DBA) suppresses glioma stemness, motility, and metabolic plasticity through inhibition of HIF‐1α signaling and synergistically enhances temozolomide activity, highlighting a potential strategy to target stemness‐driven therapeutic resistance in glioma.
Rui Zhou, Mücahit Varlı, Rundong Liu, Jieun Yu, Hyung‐Ho Ha, Jae‐Seoun Hur, Sang Kyum Kim, Hahyun Park, Hangun Kim   +8 more
wiley   +1 more source

MD‐1 Deficiency Mitigates Atherosclerosis by Inhibiting NLRP3 Inflammasome Activation via cGAS‐STING Dependent Pathway in Macrophages

Cell Proliferation, EarlyView.
MD‐1 is induced and activated in macrophages. The activated MD‐1 subsequently promotes the cGAS‐STING‐TBK1‐IRF3 signalling pathway to activate the NLRP3 inflammasome, and subsequently increases pro‐inflammatory macrophage polarisation and decreases plaque stability to accelerate the development of atherosclerosis.
Fang Zhao, Zhili Jin, Zhiwei Cai, Quan Zhang, Tao He, Xiangjie Kong, Ming Chen, Zhibing Lu, Xiaorong Hu, Wen‐Lin Cheng   +9 more
wiley   +1 more source

Reduced Risk of MASLD and Cardiometabolic Disease Following Renal Denervation Therapy in Patients With Resistant Hypertension

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Introduction Autonomic dysfunction increases the risk of cardio‐kidney‐metabolic (CKM) syndrome including metabolic dysfunction‐associated steatotic liver disease (MASLD), type 2 diabetes (T2D), cardiovascular disease (CVD) and chronic kidney disease (CKD).
Alex E. Henney, Matthew Anson, David R. Riley, Laurent Fauchier, Joel P. Giblett, Gregory Y. H. Lip, Rayaz A. Malik, Daniel J. Cuthbertson, Uazman Alam   +8 more
wiley   +1 more source

When Intraoperative Hypotension Is Not What It Seems: Systolic Anterior Motion of the Mitral Valve Causing Severe Hypotension During Noncardiac Surgery. [PDF]

Case Rep Anesthesiol
Mirrakhimov AE.
europepmc   +1 more source

Cisterna Chyli Dilation Is a Risk Factor for Liver Nodules and Hepatocellular Carcinoma in Fontan‐Associated Liver Disease: Pathophysiological Role of Lymphatic Dysfunction

Hepatology Research, EarlyView.
ABSTRACT Aim In Fontan‐associated liver disease (FALD), chronic congestion often confounds conventional fibrosis markers, complicating surveillance for hepatocellular carcinoma (HCC). Although lymphatic dysfunction is fundamental to Fontan physiology, its contribution to hepatocarcinogenesis remains unclear.
Koji Imoto, Masatake Tanaka, Takeshi Goya, Yuuki Azuma, Tomonobu Hioki, Yusuke Morita, Keisuke Sakaguchi, Nobuhiro Fujita, Takamori Kakino, Ayako Ishikita, Kenichiro Yamamura, Ichiro Sakamoto, Kousei Ishigami, Kohtaro Abe, Yoshihiro Ogawa   +14 more
wiley   +1 more source

Left Ventricular Outflow Tract Obstruction From Proximal Intimo-Intimal Intussusception: A Fatal Complication of Acute Type A Aortic Dissection. [PDF]

Cureus
Burton E, McGee JC, Vahil N, Wray T.
europepmc   +1 more source

Large Language Model‐Based Localization of Premature Ventricular Contraction Origins: A Retrospective Diagnostic Accuracy Study

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background Accurate localization of premature ventricular contraction (PVC) origin from 12‐lead electrocardiography (ECG) is important for procedural planning in catheter ablation. Although convolutional neural network (CNN)‐based models have shown promising diagnostic performance, they require task‐specific training and remain limited in ...
Kazuhisa Matsumoto, Yuya Fujisaki, Syunta Higuchi, Masataka Narita, Wataru Sasaki, Tsukasa Naganuma, Naomichi Tanaka, Daisuke Kawano, Kei Matsumoto, Wataru Yoshino, Yoshifumi Ikeda, Ritsushi Kato, Hitoshi Mori   +12 more
wiley   +1 more source

BATMAN-Assisted Valve-in-Valve TMVR With Planned Hemodynamic Support in Severe Pulmonary Hypertension. [PDF]

JACC Case Rep
Saeed M, Sabanci R, Ghumman GM, Tahir A, Baqi A, Noman A, Taleb M.   +6 more
europepmc   +1 more source