Results 251 to 260 of about 64,412 (328)

Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development

Journal of Anatomy, Volume 246, Issue 4, Page 616-630, April 2025.
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah, Anna Wilsdon, Aseel Abbad, Sophie Rochette, Frances Bu'Lock, Asma Ali Saed, Marc‐Phillip Hitz, J. David Brook, Siobhan Loughna   +8 more
wiley   +1 more source

Dynamic left ventricular outflow tract obstruction in critical illness: etiology-driven management and the role of bedside transthoracic echocardiography. [PDF]

Crit Care
Li X, Lin Y, Wang W, Zou Y, Zhang Z, Wu F, Shang J, Song Y, Liang M, Zhou Q.   +9 more
europepmc   +1 more source

The Evolving Landscape of CHD Genetics: A Contemporary Guide to Genetic Testing and Management

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Congenital heart disease (CHD) is the most common birth defect, affecting an estimated 9.4/1000 infants globally. The genetics of CHD is complex, with most cases thought to have multifactorial aetiology, implicating both genetic and environmental factors.
Bridget R. O'Malley, Gary F. Sholler, Janine Smith, Gillian M. Blue   +3 more
wiley   +1 more source

Percutaneous Management of Right Ventricular Outflow Tract Obstruction in an Adult Patient After Atrial Switch: A Case for Targeted Infundibular Ablation. [PDF]

Catheter Cardiovasc Interv
Osberghaus V, Wustmann K, Heck PB, Georgiev S, Eicken A, Ewert P, Gendera K.   +6 more
europepmc   +1 more source

Krisanaklan Reduces Intestinal Anion and Fluid Secretion Through Inhibition of Na+/K+‐ATPase and K+ Channel Activity

Annals of the New York Academy of Sciences, EarlyView.
Krisanaklan reduces CFTR‐dependent intestinal chloride and fluid secretion by inhibiting the Na+,K+‐ATPase and K+ channels in epithelial cells. Consequently, this natural, plant‐derived product may limit secretory diarrhea caused by a diverse array of microbial pathogens. However, by dissipating the transmembrane Na+ gradient, Krisanaklan also inhibits
Tessa A. Groeneweg, Erdene Baigal, Anny Leung, Gert‐Jan Kremers, Marcel J. C. Bijvelds   +4 more
wiley   +1 more source

Percutaneous management and outcomes of outflow graft obstruction in patients with left ventricular assist device: A single-center experience. [PDF]

JHLT Open
Wu Y, Baudart S, Cheng R, Kallianos K, Ruaysungnoen R, DesJardin J, Aras M, Soni K, Fiedler A, Smith J, Klein L.   +10 more
europepmc   +1 more source

Longitudinal Outcomes of Left Ventricular Outflow Tract Obstruction in Aortic Stenosis Versus Hypertrophic Obstructive Cardiomyopathy [PDF]

Jiann‐Ruey Ong, Tony Yi‐Wei Li, Aloysius Sheng‐Ting Leow, Swee‐Chye Quek, William Kong, Weiqin Lin, Ping Chai, Tiong‐Cheng Yeo, Raymond Wong, Ching‐Hui Sia, Kian Keong Poh   +10 more
openalex   +1 more source

Efficacy and Safety of the Sync‐AV II Temporary Cardiac Pacing Catheter (EASY II Trial)

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Background Cardiac pacing is crucial for patients with hemodynamically unstable bradyarrhythmias. For most indications, transvenous pacemakers are used to pace the right ventricle, causing atrioventricular dyssynchrony, which may lead to significant hemodynamic compromise.
Som A. Bailey, Bertrand Ebner, Christian Marin y Kall, Jeffrey J. Goldberger, Santiago Gallo, Eduardo J. de Marchena   +5 more
wiley   +1 more source

Multimodality imaging in hypertrophic cardiomyopathy. [PDF]

J Cardiovasc Imaging
Kim J, Lee SC.
europepmc   +1 more source

An eye on long‐duration spaceflight: Controversies, countermeasures and challenges

Experimental Physiology, EarlyView.
Abstract Space flight‐associated neuroocular syndrome (SANS) is a consequence of long‐duration space flight and is detected in two‐thirds of astronauts. In‐flight, this can cause a change in the refraction of the eyes, requiring graded hypermetropic ‘superfocus adjustable’ glasses, optic nerve head oedema and choroidal folds.
Vincent Wing Sum Ng, Susan Patricia Mollan   +1 more
wiley   +1 more source