Results 251 to 260 of about 35,692 (337)

Targeting TRPV4 to restore glymphatic system function and alleviate cerebral edema in ischemic stroke

Brain Pathology, EarlyView.
After ischemic stroke, TRPV4 activation induces cerebral edema through the TRPV4‐RhoA‐MMP9 axis: RhoA upregulates MMP9, which cleaves β‐DG to impair membrane anchoring. Subsequent β‐DG loss triggers AQP4 depolarization, disrupting GS‐mediated water homeostasis.
Yongchuan Li, Haiping Zhou, Jiaxin Xie, Mingjia Yu, Guanyu Ye, Yuzhen Zhang, Zhentong Li, Kunxue Zhang, Jingwen Wu, Sheng Xiao, Shuxin Zeng, Yuan Chang, Kaibin Huang, Suyue Pan   +13 more
wiley   +1 more source

Correction: Update on left ventricular outflow tract obstruction. [PDF]

J Cardiovasc Imaging
Song JK, Sun BJ, Kim DH, Jung SH.
europepmc   +1 more source

Hemostatic activation during cardiopulmonary bypass with different aprotinin dosages in pediatric patients having cardiac operations [PDF]

, 1993
Baranky, A., Dietrich, W., Jochum, Marianne, Meisner, H, Mossinger, H., Richter, J. A., Spannagl, Michael, Wendt, P.   +7 more
core  

Assessment of the molecular mechanisms of drug‐induced hidden cardiotoxicity by a multi‐omics approach: The example of rofecoxib

British Journal of Pharmacology, EarlyView.
Background and Purpose Hidden cardiotoxicity is defined as drug‐induced cardiotoxicity that becomes obvious only in the presence of comorbidities. However, the molecular mechanisms of hidden cardiotoxicity are not always known. Therefore, unbiased multi‐omics approaches could assist in revealing regulatory pathways.
Bennet Y. Weber, Gábor B. Brenner, Barnabás Váradi, Bence Ágg, Csenger Kovácsházi, Olivér M. Balogh, Donagh Egan, Kieran Wynne, David Matallanas, Rainer Schulz, Péter Ferdinandy, Zoltán Giricz, Anikó Görbe   +12 more
wiley   +1 more source

Update on left ventricular outflow tract obstruction. [PDF]

J Cardiovasc Imaging
Song JK, Sun BJ, Kim DH, Jung SH.
europepmc   +1 more source

Non‐canonical PKG1 regulation in cardiovascular health and disease

British Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

Hypertrophic Cardiomyopathy in a Fetus: A Rare Presentation Case Report. [PDF]

Clin Case Rep
Golbabaei A, Moghaddam ESA, Naemi M, Mohammad Talebi H.   +3 more
europepmc   +1 more source

Early dynamic left intraventricular obstruction is associated with hypovolemia and high mortality in septic shock patients [PDF]

, 2015
Bernard Bouffandeau, Dominique Jusserand, Fabrice Bauer, Jean-Baptiste Michot, Jean-Louis Chauvet, Julien Maizel, Michel Slama, Olivier Delastre, Shari El-Dash   +8 more
core   +1 more source

Elevated COMMD1 Contributes to Cardiomyocyte Copper Efflux in Chronic Myocardial Ischemia: Insights From Rhesus Monkey

Cell Proliferation, EarlyView.
Elevated COMMD1 contributes to copper efflux in cardiomyocytes during chronic ischaemia in rhesus monkey hearts, regulated by XIAP through post‐translational modification. Our findings suggest a positive feedback loop among XIAP, COMMD1 and copper efflux, contributing to ischaemic cardiomyocyte loss.
Chen Li, Da Li, Xia Cheng, Xiaoli Yuan, Ning Du, Xin Liao, Xiaorong Feng, Jie Yao, Chenglong Li, Chengxia Xie, Mu Yang   +10 more
wiley   +1 more source

Accessory mitral valve tissue causing left ventricular outflow tract obstruction associated with subaortic membrane and aortic sinus aneurysm: A case report and literature review. [PDF]

J Int Med Res
Xu J, Zhang M, Zheng N, Guo D, Wei Y.
europepmc   +1 more source