Results 41 to 50 of about 553,316 (296)
BackgroundMavacamten targets cardiac myosin ATPase, reducing the formation of actin-myosin cross-bridges, which alleviates excessive myocardial contraction and improves diastolic function.
Lijia Yang, Hongyan Dai, Yuanyuan Rong
doaj +1 more source
From Rigid to Soft Robotic Approaches for Neuroendoscopy
Robotic assistance has had minimal impact on deep intraventricular surgeries, where small‐scale, precision, and reduced invasiveness can contribute to improved patient outcomes. Emerging technologies in rigid, soft, and hybrid robotics are reviewed to identify the most promising mechanisms for deep brain navigation in addition to an attempt to identify
Kieran Gilday +3 more
wiley +1 more source
Impact of VA-ECMO on Dynamic LV Outflow Obstruction After Transcatheter Aortic Valve Replacement
Dynamic left ventricular outflow obstruction is a rare but severe complication of transcatheter aortic valve replacement. It presents as a paradoxical hemodynamic collapse after relieving the left ventricular afterload.
Juan Torrado, MD, PhD +8 more
doaj +1 more source
Transient dynamic left ventricular outflow tract obstruction
Dynamic left ventricular outflow (LVOT) obstruction has been classically described in patients with hypertrophic cardiomyopathy (HCM). The hypertrophy of the basal septum and systolic anterior motion of the mitral valve leaflet (SAM) cause dynamic LVOT ...
Gnanavelu Ganesan +2 more
doaj +1 more source
Left ventricular outflow tract obstruction after mitral valve replacement
We describe a patient with left ventricular outflow tract obstruction after mitral valve replacement preserving the anterior subvalvular apparatus. Postoperative transesophageal echocardiography demonstrated systolic narrowing of the left ventricular ...
Leclerc, Jean Louis +7 more
core +1 more source
Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic
Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang +5 more
wiley +1 more source
Flexible surgical robots are advancing minimally invasive interventions for cardiovascular diseases and cancer by enabling precise navigation through complex, submillimeter anatomical pathways. This review highlights recent innovations in actuation, bio‐integrated sensing, AI‐assisted control, and friction‐reduction technologies, discusses current ...
Hermione Truong +14 more
wiley +1 more source
Metastasizing Leiomyoma Obstructing the Right Ventricular Outflow Tract
A very loud systolic murmur was identified during a pre-operative evaluation of a 51-year-old woman for an elective hysterectomy. The TTE showed a 4.7 cm intracardiac mass obstructing the RVOT. The patient was scheduled instead for resection of the mass.
Miguel Ruben Abalo +3 more
openaire +3 more sources
Programmable Paracrine‐Mimetic Microneedle System for Temporal Regulation of Cardiac Repair
Temporal signaling is encoded into a programmable paracrine‐mimetic microneedle patch via tris(2,2'‐bipyridyl)dichlororuthenium(II) hexahydrate/sodium persulfate‐tuned hydrogel microparticles that deliver TGF‐β, IGF‐1, and VEGF over phase‐matched 7‐, 14‐, and 28‐day windows.
Yichen Dai +18 more
wiley +1 more source
Background In individuals with hypertrophic obstructive cardiomyopathy, elongated anterior mitral leaflets are commonly associated with systolic anterior motion.
Hiroyuki Nakajima +5 more
doaj +1 more source

