Results 81 to 90 of about 553,316 (296)

Surgical removal of a left ventricular myxoma in an infant

Annals of Pediatric Cardiology, 2013
Left ventricular (LV) myxoma is particularly rare in children and has not been reported in infants. A five-month-old baby presented with a myxoma arising from the anterior, lateral, and superior aspect of the LV, causing severe left ventricular outflow ...
Srinath N Reddy, G S Sunil, Raman Krishna Kumar   +2 more
doaj   +1 more source

Age‐Related Lamin B1 Deficiency Activates SLC7A11‐Dependent Disulfidptosis to Impair Osteogenesis via Intercepting Mitochondrial Fission

Advanced Science, EarlyView.
This study reveals that age‐related LMNB1 deficiency in mesenchymal stem cells epigenetically upregulates SLC7A11, triggering actin disulfidptosis and mitochondrial dysfunction. This cascade impairs bone formation in senile osteoporosis. Furthermore, researchers identified the FDA‐approved drug naldemedine as a targeted SLC7A11 inhibitor to reverse ...
Wenhui Yu, Qibo Li, Weihao Zhang, Guan Zheng, Junhua Chen, Yipeng Zeng, Zipeng Xiao, Zibin Chen, Ziqian Liu, Yangfeng Lin, Jiajie Lin, Zepeng Su, Zhongyu Xie   +12 more
wiley   +1 more source

Isolated non-obstructive accessory mitral valve tissue in an adult mimicking ruptured chordae

Indian Heart Journal, 2013
Accessory mitral valve tissue is commonly associated with other congenital heart diseases and is usually detected in children causing left ventricular outflow tract obstruction.
Prashanth Panduranga, Mohammed Al-Mukhaini   +1 more
doaj   +1 more source

Meningeal Lymphatic LTBR Deficiency Links Spinal Cord Injury to Secondary Brain Pathology

Advanced Science, EarlyView.
Spinal cord injury (SCI) induces remote brain alterations beyond the injured spinal cord. This study links dysfunction of meningeal lymphatic vessels (mLVs) to neuroinflammation and neuronal injury after SCI. LTBR‐mediated lymphatic restoration improves meningeal lymphatic integrity and neurological outcomes, highlighting LTBR as a potential regulator ...
Yi Chen, Yu Tang, Chengpeng Hu, Xiaoyan Duan, LingXia Min, Boya Cong, Chao Ma, Mingliang Tan, Ya Luo, Pengfei Wei, Minpeng Xu, Zhou Feng, Jingming Hou   +12 more
wiley   +1 more source

Anesthetic Management in Elderly High-Risk Patients with Left Ventricular Outflow Tract Obstruction - A Case Series [PDF]

Left Ventricular outflow tract Obstruction poses unique challenges in the perioperative period due to its hemodynamic implications, especially in elderly patients who often present with multiple comorbidities and decreased cardiopulmonary reserve.
Pradeep kumar, S. A. Namasivayam, Siddeshwarappa, G. Jacinto Shane
core   +1 more source

Mechanisms, pathophysiology, and diagnostic imaging of left ventricular outflow tract obstruction following mitral valve surgery and transcatheter mitral valve replacement

, 2019
© 2019 Wiley Periodicals, Inc. Left ventricular outflow tract obstruction is a serious complication of mitral valve surgery (repair and replacement) and transcatheter mitral valve replacement. An appreciation of the various mechanisms which cause outflow
Gila Perk, Christia, P., Samantha Lee, Panagiota Christia, Silbiger, J. J., Lee, S., Perk, G., Jeffrey J. Silbiger   +7 more
core   +1 more source

Human Engineered Heart Tissues Reproduce Trigger‐ and Substrate‐Driven Mechanisms of Ventricular Tachycardia

Advanced Science, EarlyView.
Engineered heart tissues (EHTs) derived from human iPSCs replicate mechanisms of ventricular tachycardia at the tissue level. Acquired Long‐QT conditions cause early afterdepolarizations, wavebreak, and transient rotors; in contrast, focal cryoinjury forms a stable substrate that supports ongoing reentry.
Matthew Fiedler, Alejandra Vasquez Limeta, Ernesto Reyes Sanchez, Leah Carter, Francisco Altamirano   +4 more
wiley   +1 more source

Unruptured congenital sinus of Valsalva aneurysm causing right ventricular outflow tract obstruction associated with hidden ventricular septal defect: a case report

BMC Cardiovascular Disorders
Background Sinus of Valsalva aneurysms are rare congenital lesions. Unruptured aneurysms are often silent, but when they are large, they can cause symptoms by compressing nearby structures.
Sajed Majadla, Saleem Majadleh, Moath Nairat, Issa Alkhdour, Yunis Daralammouri   +4 more
doaj   +1 more source

Role of Septal Myectomy in Pediatric Hypertrophic Cardiomyopathy

Kardiyovasküler Tıp E Dergisi/E Journal of Cardiovascular Medicine
Hypertrophic cardiomyopathy is a prevalent cause of sudden cardiac death among young people. This distinctive genetic condition can manifest at any age from infancy to adulthood.
Sameh M. Said
doaj   +1 more source

Aortic stenosis and left ventricular outflow tract obstruction

, 2018
Left ventricular outflow tract obstruction can occur at subvalvar, valvar, and supravalvar levels. Severity and progression can be evaluated by echocardiography.
David Anderson
core   +1 more source