Results 251 to 260 of about 87,264 (316)

Effects of a high‐sugar mixed meal on cerebrovascular haemodynamics in young, healthy versus middle‐aged adults with cardiometabolic risk factors

open access: yesExperimental Physiology, EarlyView.
Abstract Consumption of a high‐sugar mixed meal (HSMM) increases both glucose and insulin and elicits mixed vascular effects, with reduced microvascular blood flow but increased conduit artery diameter and blood flow. In this study, we sought to examine: (1) whether an HSMM elicits vascular segment‐specific effects within cerebrovasculature; and (2 ...
Krista S. Reed   +5 more
wiley   +1 more source

Cardiac‐specific Kv1.1 deficiency alters cardiomyocyte electrophysiology without modifying overall cardiac function or arrhythmia susceptibility

open access: yesExperimental Physiology, EarlyView.
Abstract The leading cause of epilepsy‐related mortality is sudden unexpected death in epilepsy (SUDEP), resulting from seizure‐induced cardiorespiratory arrest by mechanisms that remain unresolved. Mutations in ion channel genes expressed in both brain and heart represent SUDEP risk factors because they can disrupt neural and cardiac rhythms ...
Kelsey Halvorson   +11 more
wiley   +1 more source

The causative role of amyloidosis in the cardiac complications of Alzheimer's disease: a comprehensive systematic review

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic illustration of the bidirectional causative link between cerebral amyloid‐beta (Aβ) angiopathy and cardiovascular disease in Alzheimer's disease (AD). Common cardiovascular risk factors like microvascular thrombosis, diabetes, atrial fibrillation, hypertension and atherosclerosis lead to cerebral hypoperfusion and ...
Samuel Parker   +2 more
wiley   +1 more source

The Effects of Trapidil on Left Ventricular Function and Platelet Aggregation in Patients with Coronary Artery Disease Subjected to Pacing.

open access: bronze, 1991
Akira Kurita   +8 more
openalex   +2 more sources

Cellular and molecular cross‐talk in atrial fibrillation: The role of non‐cardiomyocytes in creating an arrhythmogenic substrate

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Illustration of cellular and molecular cross‐talk in atrial fibrillation. Left: a schematic of cardiac tissue showing cardiomyocytes, fibroblasts, adipocytes, inflammatory cells and the coagulation system. Right: direct and indirect cross‐talk between different cell types, with the impact of direct cross‐talk on action potential (
Zhenyu Dong   +2 more
wiley   +1 more source

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