Case Report: Overlap of long QT syndrome and catecholaminergic polymorphic ventricular tachycardia in two Chinese children with <i>CALM2</i>-related calmodulinopathy. [PDF]
Front PediatrWu J, Qi J, Liao Y.
europepmc +1 more source
An eikonal model with re‐excitability for fast simulations in cardiac electrophysiology
The Journal of Physiology, EarlyView.Abstract figure legend Restitution properties obtained from cable‐equation simulations and anisotropic remeshing informed by local fibre orientation are combined in an eikonal model with re‐excitability. The resulting reduced electrophysiology model enables efficient simulations of recurrent activation patterns, here illustrated by atrial re‐entry ...
Lia Gander +3 more
wiley +1 more source
Coronary Ectasia and Ventricular Arrhythmia in a Patient With Prior Tick Exposure and Borrelia burgdorferi IgG Seroreactivity: A Case Report. [PDF]
CureusGrigorov RK +3 more
europepmc +1 more source
Senolytics and exercise: Dual modalities for rejuvenating muscle
The Journal of Physiology, EarlyView.Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican +4 more
wiley +1 more source
Predictors of clinically diagnosed premature ventricular complexes in acute care settings: a cohort study. [PDF]
EuropaceNoubiap JJ +6 more
europepmc +1 more source
Born early, age fast: Consequences of premature birth on chronic disease and accelerated ageing
The Journal of Physiology, EarlyView.Abstract figure legend ELGANs are exposed to several postnatal pro‐oxidant stressors, including ambient and supplemental oxygen, mechanical ventilation, infections, hyperalimentation, excessive glucocorticoids and intermittent hypoxia. Since endogenous antioxidant defences are underdeveloped, this imbalance promotes oxidative stress and inflammation ...
Estelle B. Gauda +5 more
wiley +1 more source
Out-of-hospital cardiac arrest without return of spontaneous circulation after more than 2 hours: is termination of resuscitation the only option? A case report. [PDF]
Eur Heart J Case RepFernandez-Pereira J +4 more
europepmc +1 more source
Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes
The Journal of Physiology, EarlyView.Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière +6 more
wiley +1 more source
Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights
The Journal of Physiology, EarlyView.Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò +18 more
wiley +1 more source