Results 211 to 220 of about 30,644 (302)

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò   +18 more
wiley   +1 more source

An Atypical "Hot-Phase" ARVC in a PKP2 Carrier. [PDF]

open access: yesJACC Case Rep
Mutebi C   +5 more
europepmc   +1 more source

Panoramic voltage‐sensitive optical mapping of contracting hearts using cooperative multiview motion tracking with 12 cameras

open access: yesThe Journal of Physiology, EarlyView.
Abstact figure legend A panoramic 3D optical mapping system was developed, enabling imaging of action potential waves across the entire strongly deforming ventricular surface of beating isolated hearts. The system comprises 12 high‐speed cameras and a soccerball‐shaped imaging chamber with 48 light‐emitting diodes (LEDs).
Shrey Chowdhary   +5 more
wiley   +1 more source

Longer action potential duration in the Purkinje network than in the ventricular myocardium delays retrograde activation of the human His‐Purkinje system

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Activation time (AT) maps from right ventricular apical pacing in a human ventricles model with longer action potential duration in the His‐Purkinje system (HPS) than in the myocardium (MYO). For pacing with a long S1S2 coupling interval (CI), the AT from the myocardial pacing site to the first AT of the HPS (ATMYO) is longer ...
Jason D. Bayer   +3 more
wiley   +1 more source

KDM2B‐Related Neurodevelopmental Disorder A Case‐Series Supporting the CxxC Domain Phenotype With Emphasis on Ocular and Dermatologic Features

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 5, Page 1098-1104, May 2026.
ABSTRACT The KDM2B‐related neurodevelopmental disorder is a recently identified Mendelian disorder of the epigenetic machinery associated with pathogenic variants in KDM2B. Global developmental delay, intellectual disability, congenital anomalies, and systemic manifestations characterize the disorder.
Adriana Gomes   +3 more
wiley   +1 more source

Occlusion of an Intrahepatic Portosystemic Shunt With an Amplatzer Septal Occluder Device in a Dog

open access: yesVeterinary Medicine and Science, Volume 12, Issue 3, May 2026.
This is the first description, to the authors’ knowledge, of the use of an Amplatzer occluder device for a large intrahepatic shunt. In this case, shunt attenuation was successful with no major complications. Instead of accumulating coils or having to proceed with open laparotomy, the use of such device could be made routine for bigger shunt vessels of
Marion Guidat   +2 more
wiley   +1 more source

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