Results 71 to 80 of about 30,534 (282)

Dynamic Modulation of the Microenvironment Promotes Functional Maturation of Engineered Tissues

Advanced Healthcare Materials, EarlyView.
Engineered tissues lack the dynamic microenvironment of native tissues. A biocompatible, diffusible small molecule to dynamically modulate tissue microenvironments during maturation is used. Timing‐dependent modulation yields distinct outcomes, producing thicker, more native‐like blood vessels, stronger and more mature cardiac tissues, and optimized ...
Eric Silberman, Hadas Oved, Itay Gil, Amgad Marzook, Ester Sapir Baruch, Yahel Shechter, Assaf Shapira, Tal Dvir   +7 more
wiley   +1 more source

Farnesyltransferase Deficiency in Cardiomyocytes Initiates Senescence and Contributes to Cardiac Fibrosis

Advanced Science, EarlyView.
Lipid overload suppresses SREBF2‐mediated FNTB expression, leading to defective Lamin A maturation and nuclear envelope instability. This nuclear catastrophe triggers a pro‐fibrotic senescence program in cardiomyocytes. Notably, restoring nuclear integrity via AAV9‐based gene therapy effectively attenuates cardiac remodeling, identifying the ...
Yuxiao Chen, Lian Lou, Xuan Zhang, Lin Yan, Qi Zhang, Wen Shi, Jie Ding, Xu Lin, Rong Jiang, Shuo Liu, Thida Sok, Pengli Wang, Yun Mou, Jie Han, Shenjiang Hu, Xiaogang Guo, Jian Yang   +16 more
wiley   +1 more source

Ventricular dyssynchrony as a cause of structural disease in the heart of Dorper sheep

Onderstepoort Journal of Veterinary Research, 2004
Ventricular dyssynchrony is a disturbance of the normal, organized electromechanical coupling of the two ventricles. This condition has many causes, such as left bundle branch block, ventricular preexcitation, right ventricular pacing and right ...
J. Ker, E.C. Webb, C.F. Van der Merwe
doaj   +1 more source

Pseudo 2:1 AV Block From Acquired Long QT Syndrome From Eating Clay

JACC: Case Reports, 2023
Age-related degeneration of the cardiac conduction system is an important cause of heart block and a leading indication for permanent pacemaker implantations.
Kabo Mojela, MBChB, MMed, Philasande Mkoko, MBChB, MMed, MPhil, Cert Cardio, ECES   +2 more
doaj   +1 more source

Modifiable predictors of ventricular ectopy in the community [PDF]

, 2018
Background Premature ventricular contractions (PVCs) predict heart failure and death. Data regarding modifiable risk factors for PVCs are scarce. Methods and Results We studied 1424 Cardiovascular Health Study participants randomly assigned to 24-hour ...
Dewland, Thomas A, Heckbert, Susan R, Kerola, Tuomas, Marcus, Gregory M, Stein, Phyllis K, Vittinghoff, Eric   +5 more
core   +2 more sources

Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism

Advanced Science, EarlyView.
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying, Hangping Fan, Yunhe Wang, Ruhong Jiang, Dongsheng Cai, Hui Cheng, Hao Wang, Chenyang Jiang, Ping Liang   +8 more
wiley   +1 more source

Arrhythmia induction using isoproterenol or epinephrine during electrophysiology study for supraventricular tachycardia [PDF]

, 2018
Background Electrophysiology study (EPS) is an important part of the diagnosis and workup for supraventricular tachycardia (SVT). Provocative medications are used to induce arrhythmias, when they are not inducible at baseline. The most common medication
Padanilam, Benzy J., Patel, Jyoti Kandlikar, Patel, Parin J., Prystowsky, Eric N., Segar, Rachel   +4 more
core   +1 more source

Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond

Advanced Science, EarlyView.
Therapeutic gases, including NO, CO, H2S, H2, CO2, O2, and Xe, play vital roles in cellular signaling and repair. This review highlights the emerging carriers and delivery systems that enable controlled, localized gas release for diagnostic and therapeutic applications.
Syed Muntazir Andrabi, Navatha Shree Sharma, Imran Ibn Gani Rather, S. M. Shatil Shahriar, Jingwei Xie   +4 more
wiley   +1 more source

International criteria for electrocardiographic interpretation in athletes: Consensus statement. [PDF]

, 2017
Sudden cardiac death (SCD) is the leading cause of mortality in athletes during sport. A variety of mostly hereditary, structural or electrical cardiac disorders are associated with SCD in young athletes, the majority of which can be identified or ...
Aagaard, Aaron Baggish, Ackerman, Anderson, Andre La Gerche, Antonio Pelliccia, Antzelevitch, Aro, Asif, Baggish, Bakken, Basavarajaiah, Bayés de Luna, Bazett, Behr, Bent, Bent, Bessem, Biffi, Biffi, Bjørnstad, Borjesson, Brosnan, Brosnan, Brosnan, Brosnan, Calore, Calore, Calò, Carmen Adamuz, Chad A Asplund, Chandra, Chen, Chou, Christian M Schmied, Chung, Chung, Cohen, Corrado, Corrado, Corrado, Corrado, Corrado, Daubert, David M Shipon, David S Owens, Daviglus, Delise, Delise, Desai, Dhutia, Di Paolo, Domenico Corrado, Drezner, Drezner, Drezner, Drezner, Drezner, Drezner, Drezner, Dunn, Eckart, Elliott, Eugene H Chung, Exeter, Finocchiaro, Fudge, Gati, Goldenberg, Gollob, Gordon Cohen, Groh, Haghjoo, Hancock, Hank F Pelto, Harmon, Harmon, Haïssaguerre, Heidbuchel, Heidbüchel, Hein Heidbuchel, Hill, Huston, Irfan M Asif, Jack C Salerno, James, Johnson, Johnson, Jonathan A Drezner, Jordan M Prutkin, Josef Niebauer, Joseph C Marek, Junttila, Kapplinger, Kim, Kim, Kimberly G Harmon, Klein, Klein, La Gerche, Lakdawala, Le, Link, MacAlpin, Macfarlane, Magalski, Magee, Malfatto, Malhotra, Marco V Perez, Marcus, Marek, Maron, Maron, Maron, Maron, Maron, Maron, Mason, Mathew G Wilson, Mats Borjesson, Meyer, Meytes, Michael J Ackerman, Michael Papadakis, Michael S Emery, Migliore, Nasir, Nathan R Riding, Northcote, Noseworthy, Noseworthy, Novak, Papadakis, Papadakis, Pelliccia, Pelliccia, Pelliccia, Pickham, Platonov, Postema, Price, Prior, Priori, Quattrini, Ranthe, Ranthe, Rautaharju, Rawlins, Ricardo Stein, Riding, Riding, Rose, Rosso, Rowin, Ruwald, Ryan, Saguner, Sahlén, Sanjay Sharma, Sathanandam, Sawant, Schnell, Schwartz, Schwartz, Schwartz, Sharma, Sheikh, Sheikh, Sheikh, Silvana Molossi, Sohaib, Stein, Surawicz, Taggart, Takken, Tan, Tess Saarel, Tester, Tester, Tester, Tikkanen, Tikkanen, Uberoi, Uberoi, Uhm, Verdile, Victor F Froelicher, Victoria L Vetter, Vincent, Viskin, Wasfy, Weiner, Wilde, Williams, Wilson, Xiao, Zaidi, Zorzi   +198 more
core   +2 more sources

Water‐Assisted Exfoliation of HfO2‐Based Membrane for Flexible Robust Ferroelectric Synaptic Transistors

Advanced Science, EarlyView.
A flexible freestanding HfO2‐based ferroelectric membrane is achieved via a water‐assisted exfoliation technique using a Sr4Al2O₇ sacrificial layer. The BaTiO3/Hf0.5Zr0.5O2/BaTiO3 heterostructure maintains robust ferroelectricity and exhibits reliable synaptic plasticity.
Han Zhang, Miao Zeng, Jingxin Chen, Lei Wang, Sai Jiang, Qian Cao, Xuebo Li, Zekun Hou, Chun Shen, Yulin Gan, Ning Fang, Zhaoliang Liao, Ziyao Zhou, Lin Hao   +13 more
wiley   +1 more source