Results 151 to 160 of about 4,977,534 (400)

Long-term exposure to high-altitude hypoxic environments reduces blood pressure by inhibiting the renin-angiotensin system in rats

Frontiers in Physiology
IntroductionThis study assesses the effects of chronic high-altitude hypoxia on blood pressure regulation in spontaneously hypertensive rats (SHR) and normotensive Wistar-Kyoto (WKY) rats, focusing on cardiovascular remodelling, hemodynamic alterations ...
Delong Duo, Junbo Zhu, Mengyue Wang, Xuejun Wang, Ning Qu, Xiangyang Li, Xiangyang Li   +6 more
doaj   +1 more source

Loss of Hepatic Angiotensinogen Attenuates Diastolic Dysfunction in Heart Failure with Preserved Ejection Fraction

Advanced Science, EarlyView.
Increased hepatic angiotensinogen (AGT) abundance leads to cardiac diastolic dysfunction via the AngII‐independent pathway. Liver‐derived AGT is internalized by LRP2 in cardiac endothelial cells, subsequently contributing to myocardial diastolic dysfunction by suppressing microvascular angiogenesis via inhibiting the GATA2/Pim3 pathway.
Zetao Heng, Min Hong, Zhaocai Zhang, Ximing Ye, Jianan Zhou, Wentao Wu, Jiabing Rong, Yinchuan Xu   +7 more
wiley   +1 more source

Rabbit models of heart disease. [PDF]

, 2008
Human heart disease is a major cause of death and disability. A variety of animal models of cardiac disease have been developed to better understand the etiology, cellular and molecular mechanisms of cardiac dysfunction and novel therapeutic strategies ...
Bers, Donald M, Pogwizd, Steven M
core  

Intramyocardial Pressure and Strength of Left Ventricular Contraction [PDF]

, 1962
Peter F. Salisbury, Cecil E. Cross, P. Andre Rieben   +2 more
openalex   +1 more source

Multiscale Cell–Cell Interactive Spatial Transcriptomics Analysis

Advanced Science, EarlyView.
In this study, we present the MultiScale Cell‐Cell Interactive Spatial Transcriptomics Analysis method, which unites the strengths of spatially resolved deep learning techniques with a topological representation of multi‐scale cell‐cell similarity relations.
Sean Cottrell, Guo‐Wei Wei
wiley   +1 more source

Acoustic, aerodynamic, and vibrational effects of ventricular folds adduction in an ex vivo experiment

Laryngoscope Investigative Otolaryngology
Objectives The excessive adduction of ventricular folds has been observed in patients with dysphonia and professional singers. Whether these changes in the ventricular folds are the cause or just a result of disease progression remains unclear, and their
Zhixue Xiao, Jing Kang, Jinglin Su, Pingjiang Ge, Siyi Zhang   +4 more
doaj   +1 more source

Variations of Left Ventricular End-Diastolic Pressure, Volume, and Ejection Fraction with Changes in Outflow Resistance in Anesthetized Intact Dogs [PDF]

, 1968
Anastasios G. Tsakiris, R. Vandenberg, Natalio Banchero, Ralph E. Sturm, Earl H. Wood   +4 more
openalex   +1 more source

Clathrin Light Chain B Drives Hepatocellular Carcinoma Progression Through Dual Mechanisms: Small Extracellular Vesicle‐Mediated Angiogenesis and the NF‐κB–PCLAF Signaling Axis

Advanced Science, EarlyView.
Clathrin Light Chain B (CLTB) drives hepatocellular carcinoma progression through dual pathways: intracellularly, it activates the NF‐κB–PCLAF axis to enhance small extracellular vesicle (sEV) uptake and tumor proliferation; extracellularly, CLTB‐enriched sEVs bind SH3KBP1 to inhibit its degradation, inducing angiogenesis and vascular leakage ...
Xiaoke Sun, Junchen Guo, Ning Zhao, Guanghua Cui, Yun Bai, Meijuan Ding, Yi Xu, Yu Yang   +7 more
wiley   +1 more source

Production of Chronic Elevation of Left Ventricular End Diastolic Pressure in Dogs: Hemodynamic and Renal Studies [PDF]

, 1964
Charles K. Friedberg, Richard P. Lasser, D. Allen, STEPHEN E. FURST, George E. Gabor   +4 more
openalex   +1 more source

Inhibition of hypertrophy is a good therapeutic strategy in ventricular pressure overload.

Circulation, 2015
G. Schiattarella, Joseph A. Hill
semanticscholar   +1 more source