Results 161 to 170 of about 4,977,534 (400)

SpaBatch: Deep Learning‐Based Cross‐Slice Integration and 3D Spatial Domain Identification in Spatial Transcriptomics

Advanced Science, EarlyView.
SpaBatch is an end‐to‐end multi‐slice spatial transcriptomics data integration framework. It simultaneously performs embedding learning, spatial feature denoising and reconstruction, batch effect correction, and spatial domain optimization, effectively correcting batch effects and achieving accurate 3D spatial domain identification.
Jinyun Niu, Donghai Fang, Jinyu Chen, Yi Xiong, Juan Liu, Wenwen Min   +5 more
wiley   +1 more source

The Acute Effects on the Cerebral Circulation of the Reduction of Increased Intracranial Pressure by Means of Intravenous Glucose or Ventricular Drainage

, 1948
Henry A. Shenkin, Eugene B. Spitz, Francis C. Grant, Seymour S. Kety   +3 more
openalex   +1 more source

Left Ventricular Pressure-Volume Characteristics in Congenital Heart Disease [PDF]

, 1968
M. M. JARMAKANI, Sam B. Edwards, Madison S. Spach, Ramon V. Canent, Matthias Paul, MARY J. HAGAN, Roger C. Barr, Vishnu Jain   +7 more
openalex   +1 more source

Nonalcoholic Fatty Liver Disease Exacerbates the Advancement of Renal Fibrosis by Modulating Renal CCR2+PIRB+ Macrophages Through the ANGPTL8/PIRB/ALOX5AP Axis

Advanced Science, EarlyView.
The ANGPTL8/PIRB/ALOX5AP axis mediates liver‐kidney crosstalk. Hepatocytes secrete ANGPTL8, which binds to CCR2+PIRB+ macrophages in the kidneys, affecting the expression of ALOX5AP and enhancing the activation of these macrophages. Activated cells produce TGF‐β, IL‐6, and IL‐23, driving Th17 activation and promote the formation of myofibroblasts ...
Shuqi Wei, Diwen Shou, Siyuan Huang, Yingsi Wang, Quanzhen Liu, Jinfa Liu, Xiaoyu Lv, Yuyi Zeng, Liting Wei, Han Lin, Jiechuan Chen, Yangxiao Chen, Haoyu Zhong, Yanqing Zhou, Wen Ma, Li Wang, Guojun Qian, Jing Guo, Donglin Sun   +18 more
wiley   +1 more source

Left Ventricular Diastolic Pressure Elevation Consequent to Pulmonary Stenosis [PDF]

, 1969
Walter H. Herbert, Edward L. Yellin
openalex   +1 more source

Physiological response of cardiac tissue to bisphenol A: alterations in ventricular pressure and contractility.

American Journal of Physiology. Heart and Circulatory Physiology, 2015
N. Posnack, Daina Brooks, Akhil Chandra, Rafael Jaimes, N. Sarvazyan, Matthew Kay   +5 more
semanticscholar   +1 more source

Synaptic Dysfunction in the Anterior Cingulate Cortex Underlies Pain‐Anxiety Comorbidity in a Mandibular Asymmetry Mouse Model

Advanced Science, EarlyView.
This study establishes a mandibular asymmetry (MA) mouse model that recapitulates chronic orofacial pain and anxiety comorbidity. Anterior cingulate cortex (ACC) hyperactivation and synaptic dysfunction are identified as central neural mechanisms underlying these pathologies, with chemogenetic inhibition of ACC CaMKII+ neurons effectively reversing ...
Zhaoyichun Zhang, Yanran Zhang, Jialin Si, Honghui Mao, Feng He, Jin Ning, Guaiguai Ma, Xiaohua Chen, Haoxiang Xiao, Yuanyuan Zhu, Haifeng Zhang, Yifan Lu, Qian Liu, Meng Nian, Shiquan Sun, Shibin Yu, Shengxi Wu, Ze Fan, Zuolin Jin, Jing Huang   +19 more
wiley   +1 more source

Effect of l-norepinephrine on left ventricular diastolic pressures in man [PDF]

, 1968
L. Cudkowicz
openalex   +1 more source

Cold acclimation increases cardiac myofilament function and ventricular pressure generation in trout

Journal of Experimental Biology, 2014
J. Klaiman, W. Pyle, T. Gillis
semanticscholar   +1 more source

Refractory Status Epilepticus and Therapeutic Uncertainties: a Comprehensive Review on Targeting Neuroinflammation and Rationale for Developing a Platform Trial

Advanced Science, EarlyView.
Refractory status epilepticus (RSE) is a life‐threatening neurological emergency with high rates of death and long‐term disability, but treatments for it are often based on limited evidence. RSE is now understood to involve neuroinflammation, which has led to the exploration of anti‐inflammatory and immunomodulatory agents like Tocilizumab. Traditional
Shanika Samarasekera, Suneesh Thilak, Asha Patel, Prashant Nasa, Zubair Ahmed, Lorraine Jacques, William J. Scotton, Cyril Chacko, Randeep Mullhi, Ruoling Chen, Vikram Patil, Suresh Renukappa, Tonny Veenith   +12 more
wiley   +1 more source