Results 161 to 170 of about 5,069,987 (401)

Fluorinated Carnitine Derivatives as Tools to Visualise Carnitine Transport and Metabolism

Advanced Science, EarlyView.
Fluorinated carnitines, fluoromethyl carnitine (FMC) and [18F]fluoromethyl carnitine ([18F]FMC), are synthesised and established as powerful probes to interrogate carnitine biology. The multimodal detection facilitated by fluorine labelling, including 19F NMR, mass spectrometry, and positron emission tomography imaging, allowed for visualisation of ...
Richard S. Edwards, Ella‐May Hards, Sofia N. dos Santos, Hannah E. Greenwood, Madeleine E. George, Andrea Emanuelli, Muhammet Tanc, Thomas R. Eykyn, Timothy H. Witney   +8 more
wiley   +1 more source

The interventional effect of astragaloside IV on rodent models of myocardial fibrosis: a systematic review and meta-analysis

Frontiers in Pharmacology
ObjectiveThis study was conducted to evaluate the interventional effects of astragaloside in a rodent model of myocardial fibrosis (MF).MethodsData from studies related to the intervention of astragaloside IV (AS-IV) in rodent models with myocardial ...
Haozhe Li, Yunhang Chu, Yue Wang, Yue Wang, Yuan Wang, Yebo Zhang   +5 more
doaj   +1 more source

Inhibition of hypertrophy is a good therapeutic strategy in ventricular pressure overload.

Circulation, 2015
G. Schiattarella, Joseph A. Hill
semanticscholar   +1 more source

Targeting DNA‐LNPs to Endothelial Cells Improves Expression Magnitude, Duration, and Specificity

Advanced Science, EarlyView.
Attaching antibodies against endothelial cell surface proteins redirects the delivery and expression of DNA‐lipid nanoparticles to organs of interest. Our targeted nanoparticles enable organ‐selective DNA expression in the endothelium of the lungs, brain, or spleen, providing a therapeutic platform for dozens of endothelial‐centric diseases.
Nicolas Marzolini, Taylor V. Brysgel, Ryan J. Rahman, Eno‐Obong Essien, Saw Y. Nwe, Jichuan Wu, Aparajeeta Majumder, Manthan N. Patel, Sachchidanand Tiwari, Carolann L. Espy, Fengyi Dong, Sabrina A. Santos‐De León, Anit Shah, Vladimir V. Shuvaev, Elizabeth D. Hood, Liam S. Chase, Drew Weissman, Jeremy B. Katzen, David B. Frank, Mariko L. Bennett, Oscar A. Marcos‐Contreras, Jacob W. Myerson, Vladimir R. Muzykantov, Sahily Reyes‐Esteves, Jacob S. Brenner   +24 more
wiley   +1 more source

StOPping Hypertension and imprOving Children’s Lives after KidnEy TranSplantation (SOPHOCLES): study protocol for a randomized controlled multicenter trial

Trials
Background Cardiovascular disease is a major morbidity in children after kidney transplantation, limiting life expectancy and impairing graft function. Arterial hypertension is the dominant cardiovascular risk factor and highly abundant in this patient ...
Carl Grabitz, Nima Memaran, Rizky I. Sugianto, Jeanine von der Born, Mila Bukova, Elena Lehmann, Ann-Kathrin Konuhov, Dennis Holzwart, Anika Großhennig, Elke Wühl, Bernhard M. W. Schmidt, Anette Melk   +11 more
doaj   +1 more source

Right ventricular myocardial work: proof-of-concept for the assessment of pressure-strain loops of patients with pre-capillary pulmonary hypertension [PDF]

B Lacerda Teixeira, Francisco Albuquerque, Raquel B. Santos, André Ferreira, José Ricardo Carvalheiro, João Reis, L Almeida Morais, T Mano, Pedro Rio, Ana Teresa Timóteo, Rui Cruz Ferreira, A Galrinho   +11 more
openalex   +1 more source

Pharmacological inhibition of NHE3-mediated sodium absorption in the gut reduces blood pressure and attenuates impairment of left ventricular compliance [PDF]

, 2013
Dominik Linz, H. Heuer, Wendelin Frick, Armin Hofmeister, Uwe Heinelt, Petra Arndt, Uwe Schwahn, Wolfgang Linz, Michael Böehm, Hartmut Ruetten   +9 more
openalex   +1 more source

Physiological response of cardiac tissue to bisphenol A: alterations in ventricular pressure and contractility.

American Journal of Physiology. Heart and Circulatory Physiology, 2015
N. Posnack, Daina Brooks, Akhil Chandra, Rafael Jaimes, N. Sarvazyan, Matthew Kay   +5 more
semanticscholar   +1 more source

DNA Nanoflower LYTACs Enable Efficient VEGF Degradation and Verteporfin Loading for Combined Therapy of Wet Age‐Related Macular Degeneration

Advanced Science, EarlyView.
An integrated approach that combines a DNA nanoflower VEGF degrader with photodynamic therapy is developed for the treatment of wet age‐related macular degeneration, which reduces the risk of VEGF reactivation‐induced CNV recurrence and minimizes the systemic side effects associated with photodynamic therapy.
Mengxuan Li, Yan Yue, Sijin Wu, Xinyu He, Jiayi Song, Shuwen Ma, Haokun Zhang, Chenyu Xu, Song Chen, Yanming Huang, Songbo Xie, Hua Yan   +11 more
wiley   +1 more source

11 Left ventricular end diastolic filling pressure predicted by left atrial strain measured by feature tracking [PDF]

, 2016
JRJ Foley, Pankaj Garg, TA Musa, LE Dobson, Peter Swoboda, G. Fent, Philip Haaf, Sven Plein, JP Greenwood   +8 more
openalex   +1 more source