Fe‐based magnetic nanocubes conjugated with TRPV1 antibodies (FeNCs‐TRPV1) are developed for the specific targeting of TRPV1 channels. Intraspinally injected FeNCs‐TRPV1 induces TRPV1 desensitization in rats exposed to repetitive and transient ACMF.
Xueying Cheng +15 more
wiley +1 more source
Left ventricular pressure-loading improves pressure-induced right ventricular remodeling by redistributing mechanical load and reducing mechanosignaling. [PDF]
Lee XA +12 more
europepmc +1 more source
A 1-month-old infant with pulmonary hypertensive crisis after cardiac surgery was successfully rescued with connection of left atrial and right ventricular pressure measurement tubes: a case report. [PDF]
Zhang H, Song H.
europepmc +1 more source
Understanding longitudinal bi-ventricular structural and functional changes in a Pulmonary Hypertension Sugen-Hypoxia rat model by Cardiac Magnetic Resonance Imaging [PDF]
Buist, Hanna +14 more
core +2 more sources
570 Right ventricular diastolic myocardial performance index and pulmonary artery pressure [PDF]
Per Lindqvist +3 more
openalex +1 more source
TRIM40 Drives Pathological Cardiac Hypertrophy and Heart Failure via Ubiquitination of PKN2
This study identifies the E3 ligase TRIM40 as a key driver of pathological cardiac hypertrophy. TRIM40 binds PKN2 via its B‐box domain and, through its C29‐dependent catalytic activity, mediates K63‐linked ubiquitination of PKN2. This modification enhances PKN2 phosphorylation at Ser815, thereby driving hypertrophy.
Risheng Zhao +12 more
wiley +1 more source
Targeting Fibrosis in Right Ventricular Pressure Overload: Balancing on a Tightrope? [PDF]
van Wezenbeek J, de Man FS.
europepmc +1 more source
Non-invasive left ventricular pressure-volume loops from cardiovascular magnetic resonance imaging and brachial blood pressure: validation using pressure catheter measurements. [PDF]
Arvidsson PM +8 more
europepmc +1 more source

