Results 41 to 50 of about 312,190 (321)

Norepinephrine and dobutamine improve cardiac index equally by supporting opposite sides of the heart in an experimental model of chronic pulmonary hypertension

open access: yesIntensive Care Medicine Experimental, 2021
Background Pulmonary hypertension is a significant risk factor in patients undergoing surgery. The combined effects of general anaesthesia and positive pressure ventilation can aggravate this condition and cause increased pulmonary blood pressures ...
Janus Adler Hyldebrandt   +3 more
doaj   +1 more source

Influence of the elevation of the left ventricular diastolic pressure on the values of the first temporal derivative of the ventricular pressure (dP/dt) [PDF]

open access: yesArquivos Brasileiros de Cardiologia, 1999
To assess the effects of the elevation of the left-ventricular end-diastolic pressure (LVEDP) on the value of the 1st temporal derivative of the ventricular pressure (dP/dt).Nineteen anesthetized dogs were studied. The dogs were mechanically ventilated and underwent thoracotomy with parasympathetic nervous system block.
Okoshi, Katashi   +4 more
openaire   +8 more sources

Associations of Cerebrospinal Fluid Orexin‐A, Alzheimer Disease Biomarkers, and Cognitive Performance

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACTObjectiveCerebrospinal fluid (CSF) orexin‐A has been suggested to be a biomarker of Alzheimer disease (AD). In both cognitively unimpaired healthy older adults and individuals with symptomatic AD, CSF orexin‐A is positively associated with CSF Aβ42, p‐tau181, and total tau (t‐tau) concentrations.
Ruijin Lu   +13 more
wiley   +1 more source

Exercise Treadmill Testing in Moderate or Severe Aortic Stenosis: The Left Ventricular Correlates of an Exaggerated Blood Pressure Rise

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Exaggerated blood pressure response during exercise predicts future hypertension and cardiovascular events in general population and different patients groups.
Sahrai Saeed   +5 more
doaj   +1 more source

Risks and Benefits of Using a Commercially Available Ventricular Assist Device for Failing Fontan Cavopulmonary Support: A Modeling Investigation [PDF]

open access: yes, 2019
Fontan patients often develop circulatory failure and are in desperate need of a therapeutic solution. A blood pump surgically placed in the cavopulmonary pathway can substitute the function of the absent sub-pulmonary ventricle by generating a mild pressure boost.
arxiv   +1 more source

The Impact of Standard Ablation Strategies for Atrial Fibrillation on Cardiovascular Performance in a Four-chamber Heart Model [PDF]

open access: yesarXiv, 2022
Atrial fibrillation is one of the most frequent cardiac arrhythmias in the industrialized world and ablation therapy is the method of choice for many patients. However, ablation scars alter the electrophysiological activation and the mechanical behavior of the affected atria.
arxiv  

Claustrum Volume Is Reduced in Multiple Sclerosis and Predicts Disability

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The claustrum is a small, thin structure of predominantly gray matter with broad connectivity and enigmatic function. Little is known regarding the impact of claustrum pathology in multiple sclerosis (MS). Methods This study assessed whether claustrum volume was reduced in MS and whether reductions were associated with specific ...
Nicole Shelley   +5 more
wiley   +1 more source

Clinical overview on RASopathies

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, Volume 190, Issue 4, Page 414-424, December 2022., 2022
Abstract RASopathies comprise a group of clinically overlapping developmental disorders caused by genetic variations affecting components or modulators of the RAS‐MAPK signaling cascade, which lead to dysregulation of signal flow through this pathway.
Martin Zenker
wiley   +1 more source

On in-silico estimation of left ventricular end-diastolic pressure from cardiac strains [PDF]

open access: yes2024 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), pp. 1-4
Left ventricular diastolic dysfunction (LVDD) is a group of diseases that adversely affect the passive phase of the cardiac cycle and can lead to heart failure. While left ventricular end-diastolic pressure (LVEDP) is a valuable prognostic measure in LVDD patients, traditional invasive methods of measuring LVEDP present risks and limitations ...
arxiv   +1 more source

Immunosuppressive Drugs in Early Systemic Sclerosis and Prevention of Damage Accrual

open access: yesArthritis Care &Research, EarlyView.
Objective Organ damage in patients with systemic sclerosis (SSc) in individual organs such as the lungs may be prevented by receiving immunosuppressive drugs (ISs). A new measure of global organ damage, the Scleroderma Clinical Trials Consortium Damage Index (SCTC‐DI), has allowed us to investigate whether receiving ISs may reduce global organ damage ...
Murray Baron   +29 more
wiley   +1 more source

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