Results 81 to 90 of about 312,190 (321)

PRMT1 Ablation in Endothelial Cells Causes Endothelial Dysfunction and Aggravates COPD Attributable to Dysregulated NF‐κB Signaling

open access: yesAdvanced Science, EarlyView.
This study investigates the role of protein arginine methyltransferase 1 (PRMT1) in endothelial cells (ECs) in chronic obstructive pulmonary disease (COPD). Mice with endothelial‐specific PRMT1 deletion develop pulmonary hemorrhage, inflammation, and apoptosis, driven by excessive nuclear factor kappa B activation.
Thi Thuy Vy Tran   +7 more
wiley   +1 more source

Age‐related changes in the coronary microcirculation influencing the diagnostic performance of invasive pressure‐based indices and long‐term patient prognosis

open access: yesCatheterization and Cardiovascular Interventions, Volume 100, Issue 7, Page 1195-1205, December 1, 2022., 2022
Abstract Objectives Investigate age‐related changes in coronary microvascular function, its effect on hyperemic and non‐hyperemic indices of stenosis relevance, and its prognostic implications. Background Evidence assessing the effect of age on fractional flow reserve (FFR), resting mean distal intracoronary pressure/mean aortic pressure (Pd/Pa), and ...
Daniel Faria   +15 more
wiley   +1 more source

Simulation of left ventricular function during dyskinetic or akinetic aneurysm

open access: yesBiomolecules & Biomedicine, 2012
The purpose of our study was to simulate the hemodynamics of left ventricular function after left ventricular aneurysm (LVA) of various sizes and to validate the results of this computer based simulation with patient data.
Matjaž Sever   +2 more
doaj   +1 more source

Impact of blood pressure changes on myocardial work indices in hypertensive patients in a day

open access: yesThe Journal of Clinical Hypertension, 2022
Evaluating left ventricular function through instantaneous left ventricular deformation parameters might not always be accurate for patients with high fluctuations in blood pressure value due to afterload dependence.
Xinhao Li   +6 more
doaj   +1 more source

A two phase harmonic model for left ventricular function [PDF]

open access: yesarXiv, 2006
A minimal model for mechanical motion of the left ventricle is proposed. The model assumes the left ventricle to be a harmonic oscillator with two distinct phases, simulating the systolic and diastolic phases, at which both the amplitude and the elastic constant of the oscillator are different. Taking into account the pressure within the left ventricle,
arxiv  

Non-invasive assessment by B-mode ultrasound of arterial pulse wave intensity and its modification during ventricular dysfunction [PDF]

open access: yesarXiv, 2022
Arterial pulse waves contain clinically useful information: their intensity varies with cardiac performance, their speed (pulse wave velocity; PWV) depends on arterial stiffness and their reflection is affected by conduit artery tone. Here we demonstrate a novel method for non-invasively assessing wave properties.
arxiv  

The ventricular pressure-volume diagram revisited. [PDF]

open access: yesCirculation Research, 1978
The ventricular pressure-volume diagram revisited. Print ISSN: 0009-7330. Online ISSN: 1524-4571 Copyright © 1978 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation Research doi: 10.1161/01.RES.43.5.677 1978;43:677-687 Circ Res.
openaire   +3 more sources

A Novel Protein NAB1‐356 Encoded by circRNA circNAB1 Mitigates Atrial Fibrillation by Reducing Inflammation and Fibrosis

open access: yesAdvanced Science, EarlyView.
The circRNA circNAB1 is downregulated in AF patient. Silencing circNAB1 promotes collagen deposition and inflammation, whereas overexpression reduces AF susceptibility. circNAB1 encodes the protein NAB1 356 that interacts with EGR1 to mitigate fibrosis and inflammation.
William W Du   +9 more
wiley   +1 more source

Transcatheter valve repair of tricuspid regurgitation with the PASCAL system: TriCLASP study 30‐day results

open access: yesCatheterization and Cardiovascular Interventions, Volume 100, Issue 7, Page 1291-1299, December 1, 2022., 2022
Abstract Background Severe tricuspid regurgitation (TR) is independently associated with increased morbidity and mortality. Percutaneous transcatheter approaches may offer an alternative for patients not amenable to surgery. Methods TriCLASP is a prospective, single‐arm, multicenter European post‐market clinical follow‐up study (NCT04614402) to ...
Stephan Baldus   +18 more
wiley   +1 more source

Myocardial Contractions and the Ventricular Pressure--Volume Relationship [PDF]

open access: yesarXiv, 2010
We present a reduced-order heart model with the aim of introducing a novel point of view in the interpretation of the pressure-volume loops. The novelty of the approach is based on the definition of active contraction as opposed to that of active stress.
arxiv  

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