Results 151 to 160 of about 1,071,989 (385)

Trigonelline Improves Metabolism and Cardiac Function of HFpEF Mice Via Gut Microbiome Alterations‐Mediated AMPK Activation

Advanced Science, EarlyView.
Metabolomics analyses reveal that trigonelline is markedly reduced in HFpEF hearts. Trigonelline supplementation alleviates metabolic disorders and improves cardiac function in HFpEF mice via gut microbiota‐mediated AMPK activation. Abstract Heart failure with preserved ejection fraction (HFpEF) is a prevalent end‐manifestation of cardiovascular ...
Zhe Cheng, Xiaowen Wang, Jiang Yu, Xiaorong Li, Qing Tang, Can Qu, Ding Yang, Yuanjing Li, Yong Xia, Yongzheng Guo   +9 more
wiley   +1 more source

Vascular Injury After Whole Thoracic X-Ray Irradiation in the Rat [PDF]

, 2009
Purpose To study vascular injury after whole thoracic irradiation with single sublethal doses of X-rays in the rat and to develop markers that might predict the severity of injury.
Fish, B. L., Ghosh, S. N., Jacobs, Elizabeth R., Medhora, Meetha, Molthen, Robert C., Moulder, John E., Mäder, M., Wu, Q.   +7 more
core   +1 more source

Atrial fibrillation and electrophysiology in transgenic mice with cardiac-restricted overexpression of FKBP12 [PDF]

, 2019
Cardiomyocyte-restricted overexpression of FK506-binding protein 12 transgenic (αMyHC-FKBP12) mice develop spontaneous atrial fibrillation (AF). The aim of the present study is to explore the mechanisms underlying the occurrence of AF in αMyHC-FKBP12 ...
Ai, Tomohiko, Chang, Po-Cheng, Chen, Hanying, Chen, Peng-Sheng, Fishbein, Michael C., Homsi, Mohamed, Li, Bai-Yan, Lin, Shien-Fong, Liu, Jijia, Liu, Ying, Maruyama, Mitsunori, Pan, Zhenwei, Rubart, Michael, Shou, Weinian, Xiao, Deyong   +14 more
core   +1 more source

Reprogramming the Myocardial Infarction Conductive Microenvironment with Superconductive Ionic Patch for Cardiac Function Repair

Advanced Science, EarlyView.
A super‐conductive ionic patch reprograms the post‐infarction microenvironment by enabling stable ionic migration and electrical signal transmission within damaged myocardium. The patch rapidly adheres to cardiac tissue, enhances conduction velocity, suppresses excitation‐contraction decoupling, and promotes structural and functional cardiac repair in ...
Changyong Wang, Zhuang Zhang, Qi Yin, Changgeng Xu, Linlin Liang, Siwei Li, Yuwei Zhao, Chunlan Wang, Jin Zhou   +8 more
wiley   +1 more source

The relationship between different ventricular rate control levels and cardiac remodeling in early persistent atrial fibrillation: a prospective cohort study

Frontiers in Cardiovascular Medicine
BackgroundAtrial fibrillation (AF) is a prevalent cardiac arrhythmia, with ventricular rate control being a critical therapeutic target. However, the optimal range for ventricular rate control remains unclear.
Yongrong Liu, Jun Liu, Dan Wang
doaj   +1 more source

Understanding longitudinal bi-ventricular structural and functional changes in a Pulmonary Hypertension Sugen-Hypoxia rat model by Cardiac Magnetic Resonance Imaging [PDF]

, 2020
Buist, Hanna, Church, A. Colin, Gallagher, Lindsay, Holmes, William M., Hughes, Colin, Jayasekera, Geeshath, Johnson, Martin K., MacLean, Mandy R., Mullin, James, Nilsen, Margaret, Peacock, Andrew J., Uckan, Aysel, Welsh, David J., Wilson, Kathryn S., Woodward, Rosemary   +14 more
core   +2 more sources

Targeted 2‐Deoxy‐D‐Ribose Delivery by Biomimetic Nanoplatform Activates EGFR for Accelerated Heart Valve Endothelialization

Advanced Science, EarlyView.
This study develops a biomimetic nanoplatform using erythrocyte membrane‐camouflaged, CD144 antibody‐functionalized nanoparticles to deliver 2‐deoxy‐D‐ribose (2dDR). This system promotes heart valve endothelialization by enhancing endothelial cell migration and proliferation via EGFR activation, while improving hemocompatibility.
Xiang Qiu, Gaofeng Li, Wenyi Wan, Jinsheng Li, Ge Yan, Shijie Wang, Xiuqi Hu, Zongqi Han, Yazheng Shan, Ying Zhou, Nianguo Dong, Weihua Qiao   +11 more
wiley   +1 more source

Autonomous Polymer Frameworks for Sustainable Tissue‐Interfaced Plastic Bioelectronics

Advanced Science, EarlyView.
This review focuses on plastic bioelectronic systems integrated with autonomous polymer frameworks (auto‐POFs) and summarizes recent progress in this field. It provides an in‐depth analysis of the design strategies and operational mechanisms of auto‐POFs, highlighting their pivotal role in enhancing the sustainability and interfacial adaptability of ...
Elvis K. Boahen, Zhengyang Kong, So Young Kim, Hayoung Oh, Hanseo Yoo, Jeong Sub Lim, Hyun Joon Shin, Ji Hong Kim, Do Hwan Kim   +8 more
wiley   +1 more source

Differentiation of left ventricular deformation using 2D speckle tracking based on left ventricular geometric pattern in a hypertensive population: a single-center study

Arterial Hypertension
BACKGROUND: Left ventricular (LV) adaptation to arterial hypertension can result in different geometric responses with different hemodynamic patterns.
Mefri Yanni, Nani Nani, Wulan Prisilla
doaj   +1 more source

Mitral Leaflet Adaptation to Ventricular Remodeling [PDF]

, 2009
Miguel Chaput, Mark D. Handschumacher, Jorge Guerrero, Godtfred Holmvang, Jacob P. Dal‐Bianco, Suzanne Sullivan, Gus J. Vlahakes, Judy Hung, Robert A. Levine   +8 more
openalex   +1 more source