Results 311 to 320 of about 188,365 (337)

Reverse ventricular remodeling: mechanical options

Current Opinion in Cardiology, 2006
The aim of this review is to update the cardiovascular clinician on the current status of surgical therapies aimed at achieving reverse ventricular remodeling.Relevant research focusing on mechanical options for reverse ventricular remodeling will be referenced and summarized.Heart failure is a tremendous burden on society in terms of both lives lost ...
Edwin C, McGee, A Marc, Gillinov, Patrick M, McCarthy   +2 more
openaire   +2 more sources

Prevention of ventricular remodeling

Journal of Laboratory and Clinical Medicine, 1998
Abstract Despite the major advances in our understanding of the process of ventricular remodeling, many issues remain unresolved. Some relate to the ongoing question of which signals are important in initiating structural changes in the myocardium. Specifically, a better understanding of infarct zone healing may allow for reduced regional and global ...
openaire   +2 more sources

Ventricular remodeling in heart failure

Journal of Cardiac Failure, 2002
This review briefly highlights the major mechanisms of left ventricular (LV) remodeling following myocardial infarction in heart failure and presents novel strategies to limit infarct size and retard the progression of LV remodeling. This is important since interventions that have been shown to improve mortality in patients with heart failure such as ...
Mohamed A, Gaballa, Steven, Goldman
openaire   +2 more sources

Myocyte renewal and ventricular remodelling

Nature, 2002
Remaining young at heart is a desirable but elusive goal. Unbeknown to us, however, myocyte regeneration may accomplish just that. Continuous cell renewal in the adult myocardium was thought to be impossible, but multipotent cardiac stem cells may be able to renew the myocardium and, under certain circumstances, can be coaxed to repair the broken heart
Piero, Anversa, Bernardo, Nadal-Ginard
openaire   +2 more sources

Ventricular Remodeling after Myocardial Infarction

1993
Acute transmural myocardial infarction initiates a series of changes in left ventricular (LV) volume, regional function and geometry. This process, known as post-infarction LV remodeling, may continue for months or years following the initial ischemic event.
G F, Mitchell, G A, Lamas, M A, Pfeffer
openaire   +2 more sources

Aldosterone and Left Ventricular Remodeling

Hormone and Metabolic Research, 2015
AbstractExperimental and clinical evidence obtained in the last 2 decades clearly indicates that protracted exposure to inappropriately elevated aldosterone levels causes significant changes in left ventricular structure and function. Animal studies have demonstrated that aldosterone induces myocardial inflammatory changes and fibrosis in the presence ...
CATENA, Cristiana, COLUSSI, Gian Luca, Brosolo, Gabriele, Novello, Marileda, SECHI, Leonardo Alberto   +4 more
openaire   +4 more sources

Ventricular remodelling: consequences and therapy

European Heart Journal, 1993
The mammalian left ventricle can change its size and shape in response to a variety of stimuli including loss of tissue and external work. These changes in size and shape, defined as remodelling, are the sum total of a number of processes that involve the myocyte and the interstitial fibrous structures which provide the matrix in which the myocyte ...
H N, Sabbah, S, Goldstein
openaire   +2 more sources

Myocyte proliferation and ventricular remodeling

Journal of Cardiac Failure, 2002
Improvement in the methodological approach to the analysis of the myocardium has provided clear evidence of cardiac myocyte proliferation, questioning the general belief that the growth of the adult heart under physiological and pathological conditions can occur only by cellular hypertrophy.
Annarosa, Leri, Jan, Kajstura, Piero, Anversa   +2 more
openaire   +2 more sources

Global structural ventricular remodeling: Summation

Journal of Cardiac Failure, 2002
That the heart enlarges in patients with heart disease has long been known, but the structural details of this enlargement and the mechanism and rationale of this enlargement have only become apparent in recent years. As noted by Marc Pfeffer in his historical perspective, concepts were confused until quite recently.
openaire   +2 more sources

Ventricular remodeling following myocardial infarction

The American Journal of Cardiology, 1992
Ventricular remodeling denotes structural changes that occur in ventricular chamber size, wall thickness, and composition following myocardial damage. Following acute coronary occlusion, there are various factors to consider at different times that may contribute to subsequent ventricular dilation.
openaire   +2 more sources