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Circulation
BACKGROUND: Heart failure is associated with a high rate of mortality and morbidity, and ventricular remodeling invariably precedes heart failure. Ventricular remodeling is fundamentally driven by mechanotransduction that is regulated by both the nervous
Meiyan Sun +12 more
semanticscholar +1 more source
BACKGROUND: Heart failure is associated with a high rate of mortality and morbidity, and ventricular remodeling invariably precedes heart failure. Ventricular remodeling is fundamentally driven by mechanotransduction that is regulated by both the nervous
Meiyan Sun +12 more
semanticscholar +1 more source
Critical Care Nursing Clinics of North America, 2003
Ventricular remodeling is an extremely complicated process that is not well understood. There seem to be multiple feedback loops that respond to mechanical events as well as to neurohormonal stimulation, cytokine release, and other, yet unidentified, agents.
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Ventricular remodeling is an extremely complicated process that is not well understood. There seem to be multiple feedback loops that respond to mechanical events as well as to neurohormonal stimulation, cytokine release, and other, yet unidentified, agents.
openaire +2 more sources
Controversies in ventricular remodelling
The Lancet, 2006Ventricular remodelling describes structural changes in the left ventricle in response to chronic alterations in loading conditions, with three major patterns: concentric remodelling, when a pressure load leads to growth in cardiomyocyte thickness; eccentric hypertrophy, when a volume load produces myocyte lengthening; and myocardial infarction, an ...
Lionel H, Opie +3 more
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Biofactors, 2019
Left ventricular remodeling commonly complicates end-stage renal disease following chronic kidney disease (CKD). This study investigated the therapeutic efficacy of resveratrol (RSV), a polyphenolic compound, on left ventricular remodeling in subtotal ...
Peipei Li +9 more
semanticscholar +1 more source
Left ventricular remodeling commonly complicates end-stage renal disease following chronic kidney disease (CKD). This study investigated the therapeutic efficacy of resveratrol (RSV), a polyphenolic compound, on left ventricular remodeling in subtotal ...
Peipei Li +9 more
semanticscholar +1 more source
MicroRNAs in right ventricular remodelling
Cardiovascular Research, 2017Right ventricular (RV) remodelling is a lesser understood process of the chronic, progressive transformation of the RV structure leading to reduced functional capacity and subsequent failure. Besides conditions concerning whole hearts, some pathology selectively affects the RV, leading to a distinct RV-specific clinical phenotype.
Sandor, Batkai +2 more
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Ventricular remodeling and infarct expansion
The American Journal of Cardiology, 1993Infarct expansion, defined as an alteration in the ventricular topography due to thinning and lengthening of the infarcted segment, develops within the first few hours of the acute symptoms, mostly in patients with a large, transmural, anterior myocardial infarction.
ZARDINI P +4 more
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Reverse ventricular remodeling: mechanical options
Current Opinion in Cardiology, 2006The aim of this review is to update the cardiovascular clinician on the current status of surgical therapies aimed at achieving reverse ventricular remodeling.Relevant research focusing on mechanical options for reverse ventricular remodeling will be referenced and summarized.Heart failure is a tremendous burden on society in terms of both lives lost ...
Edwin C, McGee +2 more
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Prevention of ventricular remodeling
Journal of Laboratory and Clinical Medicine, 1998Abstract Despite the major advances in our understanding of the process of ventricular remodeling, many issues remain unresolved. Some relate to the ongoing question of which signals are important in initiating structural changes in the myocardium. Specifically, a better understanding of infarct zone healing may allow for reduced regional and global ...
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Ventricular remodeling in heart failure
Journal of Cardiac Failure, 2002This review briefly highlights the major mechanisms of left ventricular (LV) remodeling following myocardial infarction in heart failure and presents novel strategies to limit infarct size and retard the progression of LV remodeling. This is important since interventions that have been shown to improve mortality in patients with heart failure such as ...
Mohamed A, Gaballa, Steven, Goldman
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Myocyte renewal and ventricular remodelling
Nature, 2002Remaining young at heart is a desirable but elusive goal. Unbeknown to us, however, myocyte regeneration may accomplish just that. Continuous cell renewal in the adult myocardium was thought to be impossible, but multipotent cardiac stem cells may be able to renew the myocardium and, under certain circumstances, can be coaxed to repair the broken heart
Piero, Anversa, Bernardo, Nadal-Ginard
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