Results 121 to 130 of about 1,622,476 (293)

Human Engineered Heart Tissues Reproduce Trigger‐ and Substrate‐Driven Mechanisms of Ventricular Tachycardia

Advanced Science, EarlyView.
Engineered heart tissues (EHTs) derived from human iPSCs replicate mechanisms of ventricular tachycardia at the tissue level. Acquired Long‐QT conditions cause early afterdepolarizations, wavebreak, and transient rotors; in contrast, focal cryoinjury forms a stable substrate that supports ongoing reentry.
Matthew Fiedler, Alejandra Vasquez Limeta, Ernesto Reyes Sanchez, Leah Carter, Francisco Altamirano   +4 more
wiley   +1 more source

Recovery of global right ventricular strain in Takotsubo syndrome.

, 2018
Box (25th percentile, median, 75th percentile) and whisker (10th and 90th percentile) plots illustrating recovery of global RV strain during follow-up. RV = right ventricular.
Holger Thiele (455371), Andreas Schuster (329436), Torben Lange (4684882), Johannes T. Kowallick (640418), Joachim Lotz (640425), Uwe Raaz (5698370), Gerd Hasenfuß (326792), Christian Möller (5698367), Tobias Graf (5514566), Amedeo Chiribiri (230603), Adriana Villa (5698373), Thomas Stiermaier (5698364), Ingo Eitel (5698376)   +12 more
core   +1 more source

An Infusible Decellularized Extracellular Matrix Material Binds to Vasculature in Infarcted Myocardium and Induces Pro‐Reparative Gene Expression Following Acute Myocardial Infarction Through Inherent Avidity and Bioactive Signaling

Advanced Science, EarlyView.
To better characterize an infusible extracellular matrix (iECM) material, we applied size‐based fractionation to separate out components into two major fractions. We characterized these fractions to understand how material properties such as composition, morphology, and biochemical properties affect bioactive effects in the context of acute myocardial ...
Michael B. Nguyen, Alexander Chen, Quincy Lyons, Van K. Ninh, Maxwell C. McCabe, Colin Luo, Benjamin D. Bridgelal, Connor Uhre, Julian Cheng, Kate E. Reimold, Selena Cao, Kirk C. Hansen, Kevin R. King, Karen L. Christman   +13 more
wiley   +1 more source

Two-dimensional speckle-tracking layer-specific strain technology for evaluating left and right cardiac ventricular function among pregnant women with hypertensive disorders

Journal of Radiation Research and Applied Sciences
Background and objective: Hypertensive disorders of pregnancy (HDP) represent prevalent and severe conditions in the gestational period, which may result in multi-system impairment as well as alterations in cardiac structure and performance.
Di Zhu, Ru Ding, Chengcong Yao, Lijie Li
doaj   +1 more source

A UBE3A‐UTX Proteostasis‐Epigenetic Axis Governs Hypothalamic Energy Homeostasis

Advanced Science, EarlyView.
Ubiquitin protein ligase E3A (UBE3A) regulates hypothalamic energy homeostasis and promotes degradation of the histone demethylase UTX (KDM6A). Neuronal UBE3A loss increases susceptibility to diet‐induced obesity and is accompanied by UTX accumulation, reduced histone H3 lysine 27 trimethylation, and altered endoplasmic reticulum stress‐responsive gene
Junekyoung Lee, Jaeyoung Yoo, Young A. Kim, Zhuodu Wei, Yunseo Lee, Woo‐Jeong Shon, Je Kyung Seong, Seunghee Lee   +7 more
wiley   +1 more source

Evaluation of cardiac strain parameters in pregnant women with and without iron deficiency anemia: a prospective case control study

BMC Pregnancy and Childbirth
Background Iron deficiency anemia (IDA) is highly prevalent in pregnancy and may impair cardiovascular function. Strain echocardiography can detect subclinical myocardial dysfunction, yet data on strain alterations in pregnant women with IDA are limited.
Yunus Emre Özbebek, Eda Özden Tokalıoğlu, Ülkü Gürbüz Özbebek, Mehmet Erdoğan, Fatma Doğa Öcal, Dilek Şahin, Mehmet Akif Erdöl   +6 more
doaj   +1 more source

A Single Volatile VO2 Memristor Enabling Neuromorphic Perception, Learning, and Computing

Advanced Electronic Materials, EarlyView.
A single volatile VO2 memristor fabricated via atomic layer deposition is demonstrated as a multifunctional neuromorphic device enabled by intrinsic threshold‐switching dynamics. The device reproduces neuron‐like integration and firing, short‐timescale associative learning, temporal ECG pattern classification, and nociceptive responses to electrical ...
Bingkai Ding, Bohao Ding, Omesh Kapur, Yisong Han, Richard Beanland, Kai Sun, C. H. (Kees) de Groot, Ruomeng Huang   +7 more
wiley   +1 more source

Implantable Systems for Cardiovascular Treatment and Monitoring: Comparative Insights From Intracardiovascular and Extracardiovascular Technologies

Advanced Intelligent Systems, EarlyView.
A unifying device–cardiovascular interface framework is presented to classify implantable cardiovascular technologies as intracardiovascular blood‐contacting systems or extracardiovascular tissue‐only and blood‐handling architectures. Cross‐class comparison across shared semiquantitative criteria, including blood‐contact burden, biomimicry ...
Bergo Nicolò, Semproni Federica, Maselli Martina, Colli Andrea, Cianchetti Matteo, Ciuti Gastone, Stefanini Cesare, Menciassi Arianna   +7 more
wiley   +1 more source

Ventricular speckle tracking strain of patients with Chagas cardiomyopathy compared to idiopathic cardiomyopathy.

, 2019
Ventricular speckle tracking strain of patients with Chagas cardiomyopathy compared to idiopathic cardiomyopathy.
Manoel Otávio da Costa Rocha (7300247), Gabriel Prado Saad (7300259), Thiago Adriano de Deus Queiroz Santos (7300262), Ariela Mota Ferreira (4843035), Timothy C. Tan (7300265), Pedro Ferrari Sales da Cunha (7300253), Fernanda Rodrigues de Almeida (7300250), Stella Cristina Silva Souza (7300256), Maria Carmo Pereira Nunes (7300268), Omar Ribeiro Santos Junior (7300244)   +9 more
core   +1 more source

ADNP‐Related Helsmoortel–Van der Aa Syndrome: A Review of the Literature and Clinical Recommendations for Assessment and Monitoring

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT ADNP‐related Helsmoortel–Van der Aa syndrome (ADNP‐related HVDAS) is a single gene form of autism spectrum disorder (ASD) caused by pathogenic sequence variants in the activity‐dependent neuroprotective protein (ADNP) gene. In addition to ASD, ADNP‐related HVDAS is associated with a wide range of cognitive, behavioral, and physical health ...
Jarrett Fastman, Ana Kolevzon, Paige Siper, Tess Levy, Jeffrey M. Saland, Yitzchak Frank, Robert Rapaport, Kayla Kupietzky, William E. Bennett Jr, Bruce Gelb, Sandra Bedrosian Sermone, Alexander Kolevzon   +11 more
wiley   +1 more source