Results 121 to 130 of about 38,554 (353)

Clinical Outcomes of the POPCORN Study: Pharmacodynamics of Pre‐Operative PD1 CheckpOint Blockade and Receptor Activator of NF‐κB Ligand (RANKL) Inhibition in Non‐Small Cell Lung Cancer (NSCLC)—A Phase 1B/2 Trial

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Expanding on the growing evidence for neoadjuvant immunotherapy in resectable non‐small cell lung cancer, this study explored neoadjuvant nivolumab ± denosumab. Two of the 10 treated patients achieved a pathological complete response. CD8 T‐cell infiltration correlated with pathological response, warranting ongoing translational research to understand ...
Elizabeth Ahern, Cassie Turner, Rishendran Naidoo, David Godbolt, Amy Ives, Kirsten Popplewell, Zarnie Lwin, Sally Pearson, Kimberley Nelson, Jason Madore, William C Dougall, Brett G. M. Hughes   +11 more
wiley   +1 more source

Rate-Control or Rhythm-Contol: Where do we stand? [PDF]

, 2005
Atrial fibrillation is the most common sustained rhythm disturbance and its prevalence is increasing worldwide due to the progressive aging of the population.
A, Dello Russo, F, Andreotti, F, Bellocci, G, Pelargonio, G, Trotta, L, Testa, M, Casella   +6 more
core   +1 more source

Thoracic Epidural Anesthesia Can Be Effective for the Short‐Term Management of Ventricular Tachycardia Storm [PDF]

, 2017
Background Novel therapies aimed at modulating the autonomic nervous system, including thoracic epidural anesthesia (TEA), have been shown in small case series to be beneficial in treating medically refractory ventricular tachycardia (VT) storm. However,
Ajijola Olujimi A., Boyle Noel G., Bradfield Jason, Do Duc H., Le John, Mahajan Aman, Nogami Akihiko, Rahman Siamak, Shivkumar Kalyanam, Vaseghi Marmar, 野上 昭彦   +10 more
core   +2 more sources

Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction [PDF]

, 2019
Alexandra Schratter, Georg Delle Karth, Reinhard Achleitner   +2 more
openalex   +1 more source

Variable electrophysiology before and after block of the two delayed rectifier potassium channels in groups of isolated rabbit ventricular cells

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Between‐cell differences in ventricular cardiomyocyte action potential duration (APD) and responses to ion channel block may contribute to pro‐arrhythmic dispersion of myocardial repolarisation. This study quantifies between‐cell physiological and pharmacological variability in the rabbit left ventricle (LV) and uses ...
Rebecca J. Gilchrist, Muhamad Hifzhudin Noor Aziz, Francis L. Burton, Radostin D. Simitev, Rachel C. Myles, Godfrey L. Smith   +5 more
wiley   +1 more source

Catheter ablation for ventricular tachyarrhythmia in patients with channelopathies

Journal of Arrhythmia, 2016
Drug treatment and/or implantable cardioverter defibrillator (ICD) implantation are the most widely accepted first-line therapies for channelopathic patients who have recurrent syncope, sustained ventricular tachycardia (VT), or documented ventricular ...
Nobuyuki Murakoshi, MD, PhD, Kazutaka Aonuma, MD, PhD   +1 more
doaj   +1 more source

Effects of Endocardial Microwave Energy Ablation [PDF]

, 2005
Until recently the treatment of atrial fibrillation (AF) consisted primarily of palliation, mostly in the form of pharmacological intervention. However because of recent advances in nonpharmacologic therapies, the current expectation of patients and ...
Aquilino, Hurlé, Damián, Sánchez-Quintana, Siew Yen, Ho, Vicente, Climent   +3 more
core  

A novel selective stabilizer of the ryanodine receptor 2 prevents stress‐induced ventricular arrhythmias without impairing cardiac function

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Aberrant activation of type 2 ryanodine receptors (RyR2) causes lethal arrhythmias, such as catecholaminergic polymorphic ventricular tachycardia (CPVT). Developing drugs that suppress RyR2 hyperactivation may be key to novel arrhythmia treatments.
Nagomi Kurebayashi, Masami Kodama, Hana Inoue, Masato Konishi, Masami Sugihara, Takashi Murayama, Ryosuke Ishida, Koichiro Ishii, Shuichi Mori, Yukari Endo, Xi Zeng, Yukiko U. Inoue, Takayoshi Inoue, Satoru Noguchi, Hajime Nishio, Eri Nakashima, Norio Suzuki, Noriko Nakaya, Ryushi Sato, Yuya Otori, Ayuna Tsutsumi, Mirei Takahashi, Takayuki Oka, Haruo Ogawa, Kayoko Kanamitsu, Hiroyuki Kusuhara, Utako Yokoyama, Junko Kurokawa, Hiroyuki Kagechika, Takashi Sakurai   +29 more
wiley   +1 more source

An inappropriate shock after reprogramming tachycardia zones

Journal of Arrhythmia, 2019
A patient with an implantable cardioverter‐defibrillator (ICD) (Abbott®) had episodes of slow monomorphic ventricular tachycardia (VT) and his ICD was programmed with three tachycardia zones. During the follow‐up, he received an inappropriate shock. Upon
Rita Marinheiro, Leonor Parreira, Pedro Amador, Dinis Mesquita, Lurdes Almeida, Ana Lousinha, José Farinha, Marta Fonseca, Ana Fátima Esteves, Rui Caria   +9 more
doaj   +1 more source

Ablação epicárdica percutânea em arritmias ventriculares

Revista Portuguesa de Cardiologia, 2014
Resumo: Introdução: Os circuitos de reentrada da taquicardia ventricular envolvem, por vezes, não só o endocárdio, mas também o epicárdio. A ablação de taquicardia ventricular por via epicárdica pode ser útil nessas situações.
Pedro Galvão Santos, Diogo Cavaco, Pedro Adragão, Mauricio Scanavacca, Katya Reis Santos, Francisco Belo Morgado, Pedro Carmo, Francisco Costa, Ricardo Bernardo, Manuela Nunes, Miguel Abecasis, José Neves, Miguel Mendes   +12 more
doaj   +1 more source