Results 31 to 40 of about 54,158 (300)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

How to Create an Effective Venture Capitalist–Entrepreneur Relationship

SAGE Open, 2014
This study investigated the relationship between venture capitalists and entrepreneurs from an entrepreneur’s perspective. Its goal was to examine how perceived justice affects psychological contract breach (PCB) and how PCB evokes reactions in the ...
Edmée van Dijk, Leon Schrevel, Rosalie van Stormbroek-Burgers, Robert Jan Blomme   +3 more
doaj   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

The Moderating Role of Perceived Authenticity of Founder on the Success of High Technology Firms [PDF]

مطالعات مدیریت بهبود و تحول, 2019
In choosing among innovative ideas, venture capitalists use factors that reflect the merits of the plan and also mertis of the team. This research focuses on the factors relating to the team and examines the relation between the perceived authenticity of
Elham Yaghoobi, Mehdi Kiamehr
doaj   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Entrepreneurs' Access to Private Equity in China: The Role of Social Capital [PDF]

, 2002
Drawing on Social network theory, this article argues for enhancing effects of social capital of entrepreneurs on investment selection decisions of venture capitalists (to invest versus not to invest), and main effects of social capital on investment ...
Batjargal, Bat, Liu, Mannie M.
core   +2 more sources

Multistage Effort and the Equity Structure of Venture Investment Based on Reciprocity Motivation

Discrete Dynamics in Nature and Society, 2015
For venture capitals, it is a long process from an entry to its exit. In this paper, the activity of venture investment will be divided into multistages.
Chuan Ding, Jiacheng Chen, Xin Liu, Junjun Zheng   +3 more
doaj   +1 more source

The role of venture capitalists in the regional innovation ecosystem : a comparison of networking patterns between private and publicly backed venture capital funds [PDF]

, 2017
This paper empirically examines the development of social networks among venture capitalists and other professionals of the regional innovation ecosystem.
A Bergek, A Saxenian, AK Gupta, C Mason, C Mason, C Mason, C Mason, C Mason, C Mueller, CM Mason, D Bergemann, D Rosenberg, D Schäfer, DJ Storey, E Lutz, E Norton, George Saridakis, H Sapienza, H Sapienza, J Lerner, J Lerner, J Lerner, J Martin, JM Wooldridge, JR Lindner, L Buzzacchi, M Fritsch, M Kenney, M Landabaso, M Mäkelä, M Porter, M Porter, M Porter, M Porter, M Porter, MA Zook, ME Porter, O Sorenson, P Cooke, P Cooke, P Cooke, P Cooke, P Cooke, P Cooke, P Gompers, P Gompers, P Nightingale, P Sunley, PM Podsakoff, R Baron, R Florida, R Gulati, R Martin, S Bowles, S Pinch, S Shane, S Venkataraman, SN Kaplan, T Hellman, TH Lin, V Kanniainen, VH Fried, W Powell, WB Bygrave, Y Hochberg, Y Pierrakis, Yannis Pierrakis   +66 more
core   +2 more sources

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

DOES VENTURE CAPITAL AFFECT CROWDFUNDING PERFORMANCE?

Economic Review, 2021
This study quantitatively discusses the relationship among venture capitalists, entrepreneurs, and crowdfunders. It considers the effectiveness of venture capital on the performance of crowdfunding campaigns started by entrepreneurs.
Chia-Ling Chang, Yen-Sheng Lee, Han-Kun Tien   +2 more
doaj   +2 more sources