Results 131 to 140 of about 26,408 (229)

Multivalent antibody‐based conjugates as new tools for tailored modulation of G protein–coupled receptors

British Journal of Pharmacology, Volume 183, Issue 16, Page 4512-4531, August 2026.
The G protein–coupled receptor (GPCR) superfamily consists of the most common targets of approved drugs. Targeting GPCRs offers appealing avenues for therapeutic development. Antibodies and their fragments, such as single‐domain antibodies (VHHs or nanobodies), have emerged as useful alternatives to small molecule pharmacophores as building blocks in ...
Shivani Sachdev, Ross W. Cheloha
wiley   +1 more source

Evaluation of the Venus P-valve for transcatheter pulmonary valve replacement in patients with right ventricular outflow tract dysfunction. [PDF]

Future Cardiol
Ayyash BM, Hijazi ZM.
europepmc   +1 more source

The Role of Dice in the Emergence of the Probability Calculus

International Statistical Review, Volume 94, Issue 2, Page 464-483, August 2026.
Summary The early development of the probability calculus was clearly influenced by the roll of dice. However, while dice have been cast since time immemorial, documented calculations on the frequency of various dice throws date back only to the mid‐13th century.
David R. Bellhouse, Christian Genest
wiley   +1 more source

Kinase KEY1 controls pyrenoid condensate size throughout the cell cycle by disrupting phase separation interactions. [PDF]

Nat Cell Biol
He S, Lemma LM, Martinez-Calvo A, He G, Hennacy JH, Wang L, Ergun SL, Rai AK, Wang C, Bunday L, Kayser-Browne A, Wang Q, Brangwynne CP, Wingreen NS, Jonikas MC.   +14 more
europepmc   +1 more source

Deep Margin Elevation With Various Resin Composites: Effect of Thermomechanical Aging on the Marginal Gap of CAD/CAM Inlays

Journal of Esthetic and Restorative Dentistry, Volume 38, Issue 8, Page 1518-1526, August 2026.
ABSTRACT Objective This in vitro study evaluated the effects of composite material type, margin design (deep margin elevation vs. control), and thermomechanical aging on the marginal gap of CAD/CAM inlay restorations. Materials and Methods Standardized mesio‐occluso‐distal (MOD) inlay cavities were prepared in extracted human molars, with mesial ...
Zeliha Şanıvar Abbasgholizadeh, Ezgi Göler   +1 more
wiley   +1 more source

Dual-site phosphorylation of SLX4 stabilizes the SLX4-MUS81 interface to promote mitotic SMX assembly and genome protection. [PDF]

Nucleic Acids Res
Payliss BJ, Yun HY, Doshi S, Lemak A, Tse YWE, Aprosoff CM, Houliston S, Arrowsmith CH, Wyatt HDM.   +8 more
europepmc   +1 more source

Light Element Exsolution in Fe‐Si‐C‐(H) System: A Mechanism for Powering Mercury's Early Core Dynamo

Geophysical Research Letters, Volume 53, Issue 14, 28 July 2026.
Abstract Mercury is one of the few terrestrial planets in the solar system with a magnetic field, yet the energy source to power its core dynamo remains unclear to date. Si, C, and possibly H are the top candidate light elements for its liquid core. Here, we showed experimentally that Si, C, and H in Fe‐Si‐C and Fe‐Si‐C‐H liquids share a simultaneous ...
Yuanjing Li, Liangliang Zhang, Fabin Pan, Xiaojing Lai, Xiang Wu, Feng Zhu   +5 more
wiley   +1 more source

Rheological and Structural Evaluation of Dental Flowable Composites for Optimized Performance in Transparent Aligner Systems. [PDF]

Polymers (Basel)
Palmieri E, Cataldi ME, Cerroni L, Montaina L, Bonomo M, Petrone G, Bellisario D, Mattiello L, Pasquantonio G, Liscio A, Maita F, Maiolo L, Condò R.   +12 more
europepmc   +1 more source

Martian Magnetotail Neutral Sheet Asymmetry Driven by Heavy Planetary Pickup Ions

Geophysical Research Letters, Volume 53, Issue 13, 16 July 2026.
Abstract In the induced magnetotail of Mars, the neutral sheet is an important channel for atmospheric ion escape, yet the role of heavy planetary pickup ions in shaping its geometry has been unclear. Using three‐dimensional hybrid simulations, we demonstrate that these ions induce a global neutral sheet asymmetry via mass loading.
Jingyi Zhou, Zhenpeng Su, Kaijun Liu, Rentong Lin, Esa Kallio, Riku Jarvinen, Yuming Wang   +6 more
wiley   +1 more source

Modeling pediatric low-grade glioma heterogeneity using human forebrain organoids. [PDF]

Mol Cancer
Leva G, Santomaso L, Gianesello M, Patrizi S, Ress F, Cocchini F, Antonacci C, Gianno F, Abballe L, Lago C, Pozza N, Trentini G, Cardano M, Minasi S, Buttarelli FR, Antonelli M, Pernici D, Petrucci L, Antonica F, Busarello E, Iannuzzi M, Soldano A, Tebaldi T, Miele E, Ferretti E, Tiberi L.   +25 more
europepmc   +1 more source