Results 221 to 230 of about 281,101 (262)
Progress on the development of Class A GPCR‐biased ligands
British Journal of Pharmacology, Volume 182, Issue 14, Page 3249-3300, July 2025.Class A G protein‐coupled receptors (GPCRs) continue to garner interest for their essential roles in cell signalling and their importance as drug targets. Although numerous drugs in the clinic target these receptors, over 60% GPCRs remain unexploited. Moreover, the adverse effects triggered by the available unbiased GPCR modulators, limit their use and
Paula Morales +20 more
wiley +1 more source
Discussion of Greenwich Observations of Venus, 1869-1900 [PDF]
, 1906 P. H. Cowell
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British Journal of Pharmacology, Volume 182, Issue 14, Page 3225-3248, July 2025.G protein‐coupled receptors (GPCRs) play a crucial role in cell function by transducing signals from the extracellular environment to the inside of the cell. They mediate the effects of various stimuli, including hormones, neurotransmitters, ions, photons, food tastants and odorants, and are renowned drug targets.
Małgorzata M. Kogut‐Günthel +11 more
wiley +1 more source
Diabetic Medicine, Volume 42, Issue 7, July 2025.Abstract Aims The MiniMed™ 780G improves glycaemia and reduces burden in type 1 diabetes. We investigated how new all‐in‐one “Simplera Sync™” sensors and 7‐day Extended™ Wear Infusion Sets (EIS) affect glycaemia and system performance in young people with previously elevated HbA1c levels (≥69 mmol/mol [≥8%]) after transitioning from 780G with Guardian ...
Venus R. Michaels +8 more
wiley +1 more source
Ion Escape From Degenerate Induced Magnetospheres: The Case of Mars
Geophysical Research Letters, Volume 52, Issue 12, 28 June 2025.Abstract When the cone angle of the interplanetary magnetic field (IMF) becomes small, induced magnetospheres of unmagnetized planets degenerate. Using hybrid simulations, we study ionospheric ion escape in a 4° cone angle case and compare it with the nominal 55° cone angle (Parker spiral) case. The total escape rate is 1.7×1025 $1.7\times 1{0}^{25}$ s−
Qi Zhang +7 more
wiley +1 more source
Some Remarks on the Method of the Astronomer Royal for ascertaining the Difference between the true and spurious Disc of Venus [PDF]
Sheepshanks
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Prospects of Using Tidal Tomography to Constrain Ganymede's Interior
Geophysical Research Letters, Volume 52, Issue 11, 16 June 2025.Abstract Juice (JUpiter ICy moons Explorer) 3GM Radio Science Experiment will map the gravitational field of Ganymede with unprecedented accuracy and measure tidally‐induced variations. These measurements will allow the characterization of its putative ocean and may resolve lateral variations in internal structure.
M. Rovira‐Navarro +5 more
wiley +1 more source
Relativistic perihelion precession of orbits of Venus and the Earth
Open Physics, 2008 Biswas Abhijit, Mani Krishnan
doaj +1 more source
On the Position of Venus during the Total Eclipse of July 18, 1860 [PDF]
Chevallier
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