Results 181 to 190 of about 32,289 (262)

Impact of Metformin and Diabetes on Tumor Response to Total Neoadjuvant Therapy in Advanced Rectal Cancer: A Multicenter Retrospective Cohort Study

Asia-Pacific Journal of Clinical Oncology, EarlyView.
In advanced rectal cancer patients receiving total neoadjuvant therapy (TNT), overall tumor response did not differ by diabetes status or metformin use. However, among diabetic patients, metformin use was associated with higher overall complete response rates. These findings suggest a potential benefit of metformin in enhancing TNT response in diabetic
Sergei Bedrikovetski, Mahima Raju, Tracy Fitzsimmons, Ishraq Murshed, Timothy J. Price, Michael Penniment, Sudarsha Selva‐Nayagam, Tarik Sammour   +7 more
wiley   +1 more source

Why did Putin invade Ukraine? A theory of degenerate autocracy

American Journal of Political Science, EarlyView.
Abstract Many dictatorships end up with a series of disastrous decisions such as Hitler's attack on the Soviet Union or Saddam Hussein's aggression against Kuwait. Even if a certain policy choice is not ultimately fatal for the regime, such as Mao's Big Leap Forward or the Pol Pot's collectivization drive, they typically involve both a miscalculation ...
Georgy Egorov, Konstantin Sonin
wiley   +1 more source

Contesting repression in divided democracies: Can counternarratives reduce support for police violence?

American Journal of Political Science, EarlyView.
Abstract Democracies often struggle to contain police violence, which undermines the rule of law and reproduces inequality by targeting marginalized citizens. Yet, scholars have shown that repressive policing enjoys considerable public support. Focusing on Brazil, we demonstrate that attitudes toward police violence mirror polarization between left ...
Yanilda María González, Natán Skigin
wiley   +1 more source

Management of locally advanced lynch syndrome rectal cancer during pregnancy with neoadjuvant immunochemotherapy: a case report. [PDF]

Front Oncol
Fan S, Li X, Shi L, Dong J.
europepmc   +1 more source

Addressing inequities in the design and delivery of prehabilitation in the UK: case studies of challenges, complexities and good practice*

Anaesthesia, EarlyView.
Summary Introduction Prehabilitation has become increasingly prominent in the context of cancer surgery. While prehabilitation offers significant benefits, it can also inadvertently broaden inequalities because it is often more accessible to some than others.
Charlotte Hadley, Xiubin Zhang, Hilary Stewart, Sophie Stanley, Ces Kulikowski, Andrea Partridge, Laura Wareing, Lisa Ashmore, Christopher Gaffney, Jo Rycroft Malone, Andrew Smith, Cliff Shelton   +11 more
wiley   +1 more source

Organ preservation with total neoadjuvant therapy in early-stage rectal cancer: A statewide analysis. [PDF]

Colorectal Dis
Bunjo Z, Fitzsimmons T, Nguyen TM, Penniment M, Selva-Nayagam S, Tonkin D, Sia TC, Murphy E, Thomas M, Sammour T.   +9 more
europepmc   +1 more source

The Vicissitudes of the Nafs: Madness, Paralysis, and the Work of Transgression in Sufi Ethics

Anthropology of Consciousness, EarlyView.
ABSTRACT How should we theorize Sufi ethics when the practice of zikr (remembrance) that leads to spiritual enlightenment (tazkiyya) might also bring one to the brink of majzubiyat (madness)? What forms of regulation or restraint are imagined or enacted by practitioners to prevent spiritual boundlessness from perverting into its underside of paralysis (
Muhammad Osama Imran
wiley   +1 more source

Acute Intermittent Hypoxia Exerts Beneficial Effects and Promotes Repair in Male Mice in the Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis. [PDF]

Glia
Tokarska N, Roberts J, Koralage SR, Naniong JMA, Johnston JM, Wei Z, Verge VMK.   +6 more
europepmc   +1 more source

The Tutopatch® assisted surgery for complex strabismus study: TASCS‐study

Acta Ophthalmologica, EarlyView.
Abstract Purpose To investigate the efficacy of tendon elongation using bovine pericardium (Tutopatch®) in complex strabismus surgeries, with a specific focus on longer follow‐up of postoperative outcomes and patient satisfaction. Methods In this pre‐post cohort study, the records of all patients who underwent tendon elongation strabismus surgery with ...
Ires A. W. Verhees, Hinke Marijke Jellema, Anne‐Marie E. L. Langenhorst, B. Jeroen Klevering, Laurentius J. van Rijn, Annabel L. W. Groot   +5 more
wiley   +1 more source

Nomogram based on Prognostic Nutritional Index (PNI) for predicting acute radiation proctitis in locally advanced rectal cancer patients with neoadjuvant chemoradiotherapy. [PDF]

PeerJ
Wang Y, Hong Y, Wang Y, Lin J, Guan H, Zhou Z, Xu B.   +6 more
europepmc   +1 more source