Results 231 to 240 of about 2,058,291 (283)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

How much of a face is a face: exploring reidentification potential with generative AI. [PDF]

J Med Imaging (Bellingham)
Cho C, Liu Y, Jiang B, McNeil AJ, Dawant BM, Landman BA, Tkaczyk ER.   +6 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

From In Silico Hypothesis to Validation: The Role of Real-World Evidence in the Preliminary Verification of AI-Generated Drug-Repositioning Candidates: A Comprehensive Review. [PDF]

J Clin Med
Gałuszewski M, Olszewski J, Jankowska K, Wójcik K, Bielecka-Wajdman A.   +4 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Influencing Factors, Construction and Verification of a Nomogram Model for Adolescent Depression With Nonsuicidal Self-Injury Behaviour. [PDF]

Actas Esp Psiquiatr
Lu F, Li M, Cai Z, Huang X.
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

An integrated framework for proactive deepfake mitigation via attention-driven watermarking and blockchain-based authenticity verification. [PDF]

Sci Rep
Hajjej F, Hamid M, Alluhaidan AS.
europepmc   +1 more source

Multimodal assessment of exercise-induced fatigue: integrating cardiopulmonary, neuromuscular, and biomechanical profiling in high-intensity running. [PDF]

Front Sports Act Living
Wang Y, Chen A, Xu Y, Tao X, Wang J, Li H, Ouyang W.   +6 more
europepmc   +1 more source

A knowledge-driven framework for surgical safety check integration using speech recognition and speaker verification. [PDF]

Front Neurosci
Shi W, Fan R, Hu J, Wang J, Bian M, Jiang W.   +5 more
europepmc   +1 more source