Results 41 to 50 of about 828,996 (313)

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

Towards inferring reactor operations from high-level waste

open access: yesNuclear Engineering and Technology
Nuclear archaeology research provides scientific methods to reconstruct the operating histories of fissile material production facilities to account for past fissile material production.
Benjamin Jung   +2 more
doaj   +1 more source

System Verification through Program Verification

open access: yes, 2011
We present an automatable approach to verify that a system satisfies its requirements by verification of the program that controls the system. The approach can be applied if the interaction of the program with the system hardware can be faithfully described by a table relating domain phenomena and program variables.
Dietsch, Daniel   +2 more
openaire   +3 more sources

Verification bias [PDF]

open access: yesBMJ Evidence-Based Medicine, 2018
This article is part of the Catalogue of Bias series. We present a description of verification bias, and outline its potential impact on research studies and the preventive steps to minimise its risk. We also present teaching slides in the online supplementary file.
O'Sullivan, J   +3 more
openaire   +3 more sources

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

Library stock verification: a ritual and an occupational hazard [PDF]

open access: yes, 1991
Explains the sensitive, controversial stock verification as one of the occupational hazards and a postmortem, emphasises need for clarity of objectives and procedures regarding stock verification and responsibilities of loss, points out that the cost of ...
Sridhar, M. S.
core  

Discussion on Influencing Factors of Validation of Cleaning Process in Manufacture of Implantable Medical Devices

open access: yesZhongguo yiliao qixie zazhi
Cleaning process validation is an important guarantee for implantable medical devices to ensure product cleanliness. In the manufacturing process, implantable devices usually need to control pollution through cleaning process to achieve a certain ...
Xin LIU, Xiaofei MA
doaj   +1 more source

Infrastructure-Based Digital Twins for Cooperative, Connected, Automated Driving and Smart Road Services

open access: yesIEEE Open Journal of Intelligent Transportation Systems, 2023
Driving requires continuous decision making from a driver taking into account all available relevant information. Automating driving tasks also automates the related decisions.
Elvira Thonhofer   +7 more
doaj   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli   +3 more
wiley   +1 more source

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