Results 31 to 40 of about 349,112 (272)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
International Journal of Behavioral Nutrition and Physical Activity, 2010 Background Few studies, if any, have examined the impact of a weight control program on the home food environment in a diverse sample of adults. Understanding and changing the availability of certain foods in the home and food storage practices may be ...
West Delia +2 more
doaj +1 more source
Pilot trial comparing COVID-19 publication database to conventional online search methods
BMJ Health & Care Informatics, 2022 Background and objectives Literature review using search engines results in a list of manuscripts but does not provide the content contained in the manuscripts.
Takamaru Ashikaga +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
The Town That Food Saved: How One Community Found Vitality in Local Food
Journal of Agriculture, Food Systems, and Community Development, 2016 First paragraphs: I picked up the book The Town That Food Saved: How One Community Found Vitality in Local Food with a healthy dose of skepticism. The title sounds like a booster for how the local food movement can bring prosperity, not to mention ...
Valerie Imbruce
doaj +1 more source
Advanced Functional Materials, EarlyView.This work explores Li‐substituted P2 layered oxides for Na‐ion batteries by crystallographic and electrochemical studies. The effect of lithium on superstructure orderings, on phase transitions during synthesis and electrochemical cycling and on the interplay of O‐ versus TM‐redox is revealed via various advanced techniques, including semi‐simultaneous
Mingfeng Xu +5 more
wiley +1 more source
Increasing Local Procurement in Farm to School Programs: An Exploratory Investigation
Journal of Agriculture, Food Systems, and Community Development, 2016 Farm-to-school (FTS) programs have become more widely adopted in recent years because of their potential to mitigate childhood obesity, as well as their economic development and educational benefits.
Erin Roche +2 more
doaj +1 more source
Advanced Functional Materials, EarlyView.Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley +12 more
wiley +1 more source
Journal of Medical Education and Curricular Development, 2023 OBJECTIVES Improved knowledge of hepatitis C virus (HCV) screening, linkage to care, and treatment is needed among nonspecialist medical professionals to combat the HCV epidemic. The authors sought to implement and analyze the impact of an HCV curriculum
Andrew J. Hale, Steven D. Lidofsky
doaj +1 more source