Results 71 to 80 of about 2,849 (199)

Dupilumab‐related ocular surface disorders in a paediatric cohort with atopic dermatitis, treated in a tertiary paediatric hospital in London

JEADV Clinical Practice, Volume 3, Issue 5, Page 1558-1563, December 2024.
Schematic representation of 46 paediatric patients receiving dupilumab for atopic dermatitis, highlighting the main study findings of a 26.1% incidence of dupilumab‐related ocular surface disorders (DROSD), mean time to DROSD development of 4.1 months with further characterisation of the specific ophthalmological findings. Abstract Background Dupilumab
Anjali Rampersad, Karolina Gholam, Lea Solman, Natalia Cartledge, Sri Gore, Gabriela Petrof   +5 more
wiley   +1 more source

Vernal keratoconjunctivitis: Signs, symptoms and therapeutic management

, 2001
Allergic eye conditions are particularly common anterior eye problems and their incidence seems to be increasing. Vernal keratoconjunctivitis is a potentially severe, chronic, allergic condition, that typically occurs in males, commending between eight ...
Schmid, Katrina L., Swann, Peter G.
core  

Vernal Keratoconjunctivitis: an update focused on clinical grading system [PDF]

, 2019
Vernal keratoconjunctivitis (VKC) is a severe disease with a prevalence of < 1 case out of 10,000 in Europe, which occurs mainly in pediatric age and is characterized by a severe and often bilateral chronic inflammation of the ocular surface.
De Castro, G, Perri, L, Duse, M, Leonardi, L, Loffredo, L, Zicari, A M, Spalice, A, Capata, G, Nebbioso, M, Midulla, F   +9 more
core   +1 more source

A STUDY TO EVALUATE AND COMPARE THE EFFICACY AND SAFETY OF TOPICAL CYCLOSPORINE-A 0.5% WITH TOPICAL PLACEBO (ARTIFICIAL TEARS) IN ALLEVIATING THE CLINICAL FEATURES ASSOCIATED WITH VERNAL KERATOCONJUNCTIVITIS

National Journal of Medical Research, 2016
Introduction: Vernal keratoconjunctivitis is a severe, typically seasonal recurrent ocular inflammatory disorder. Topical cyclosporine-A is inhibitory to many T-cell dependent inflammatory mechanisms which are likely to play role in treatment of vernal ...
Abha Gahlot, Rupali Maheshgauri, Bhargav Kotadia, Kanisha Jethwa, Gira Raninga   +4 more
doaj  

The epithelial barrier theory and its associated diseases

Allergy, Volume 79, Issue 12, Page 3192-3237, December 2024.
Abstract The prevalence of many chronic noncommunicable diseases has been steadily rising over the past six decades. During this time, over 350,000 new chemical substances have been introduced to the lives of humans. In recent years, the epithelial barrier theory came to light explaining the growing prevalence and exacerbations of these diseases ...
Na Sun, Ismail Ogulur, Yasutaka Mitamura, Duygu Yazici, Yagiz Pat, Xiangting Bu, Manru Li, Xueyi Zhu, Huseyn Babayev, Sena Ardicli, Ozge Ardicli, Paolo D'Avino, Ayca Kiykim, Milena Sokolowska, Willem van de Veen, Lukas Weidmann, Deniz Akdis, Banu Goker Ozdemir, Marie Charlotte Brüggen, Luc Biedermann, Alex Straumann, Andrea Kreienbühl, Emma Guttman‐Yassky, Alexandra F. Santos, Stefano Del Giacco, Claudia Traidl‐Hoffmann, David J. Jackson, De‐Yun Wang, Antti Lauerma, Heimo Breiteneder, Luo Zhang, Liam O'Mahony, Oliver Pfaar, Robyn O'Hehir, Thomas Eiwegger, Wytske J. Fokkens, Beatriz Cabanillas, Cevdet Ozdemir, Walter Kistler, Mahmut Bayik, Kari C. Nadeau, Maria J. Torres, Mübeccel Akdis, Marek Jutel, Ioana Agache, Cezmi A. Akdis   +45 more
wiley   +1 more source

Benefit delayed immunosenescence by regulating CD4+T cells: A promising therapeutic target for aging‐related diseases

Aging Cell, Volume 23, Issue 10, October 2024.
CD4+T cells play a notable role in immune protection at different stages of life. During aging, the interaction between the body's internal and external environment and CD4+T cells, results in a series of changes in the CD4+T cells pool making it involved in immunosenescence. CD4+T cells subsets aging as a treatment focus, offering novel approaches for
Tingting Xia, Ying Zhou, Jiayao An, Zhi Cui, Xinqin Zhong, Tianyi Cui, Bin Lv, Xin Zhao, Xiumei Gao   +8 more
wiley   +1 more source

Comparison of Cyclosporine and Steroids in Treating Severe Allergic Conjunctivitis in Children: an Evidence-based Case Report

Journal of Agromedicine and Medical Sciences (AMS)
The efficacy of cyclosporine compared with corticosteroid in reducing symptoms and signs in children with severe allergic conjunctivitis, either in vernal keratoconjunctivitis or atopic keratoconjunctivitis, is still unknown.
Muhammad Ilham Dhiya Rakasiwi, Julie Dewi Barliana, Afid Brilliana Putra, Muhammad Imran Khan Ismail, Awliya Awliya, Gusti Candra Pamungkas, Nida Ghitha Aulia   +6 more
doaj   +1 more source

Development and testing of the quality of life in children with vernal keratoconjunctivitis questionnaire

, 2007
To develop and validate a questionnaire that measures health-related quality of life (HRQoL) in children with vernal keratoconjunctivitis (VKC)
Bonini, Stefano, Gramiccioni, Claudia, Baiardini, Ilaria, Bonini, Sergio, SACCHETTI, MARTA, Fassio, Omar, LAMBIASE, ALESSANDRO, Aronni, Silvia   +7 more
core   +1 more source

The Safety and Effectiveness of 0.03% Tacrolimus in Pediatric Patients Presenting with Vernal Keratoconjunctivitis in Children Hospital, Multan

Life and Science
Objective: This study evaluated the safety and effectiveness of tacrolimus (0.03%) ointment in treating pediatric patients with vernal keratoconjunctivitis. Study Design: A prospective, interventional study.
Muhammad Ajmal Chaudhary, Muhammad Saad Ullah, Muhammad Younis Tahir, Razaullah Khan, Sajjad Muhammad Haider   +4 more
doaj   +1 more source

Ocular surface disease in pediatric patients with moderate‐to‐severe atopic dermatitis

Pediatric Allergy and Immunology, Volume 36, Issue 2, February 2025.
Lisa P. van der Rijst, Nienke Veldhuis, Sara van der Kamp, Roselie E. Achten, Chantal M. van Luijk, Elsbeth S. M. Voskuil‐Kerkhof, Inge M. Haeck, Marjolein S. de Bruin‐Weller, Marlies de Graaf   +8 more
wiley   +1 more source