Results 81 to 90 of about 924,552 (343)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

What tone teaches us about language [PDF]

open access: yes, 2018
In ‘Tone: Is it different?’ (Hyman 2011a), I suggested that ‘tone is like segmental phonology in every way—only more so’, emphasizing that there are some things that only tone can do.
Hyman, LM
core  

A Tissue Engineering product development pathway [PDF]

open access: yes, 2012
Tissue engineering is a field of inquiry and research that uses engineering techniques and principles of biological sciences to develop functional substitutes for reconstruction of damaged organs.
Falvo D'Urso Labate, Giuseppe Vittorio Ugo
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Bits and q-bits as versatility measures

open access: yesAnais da Academia Brasileira de Ciências, 2004
Using Shannon information theory is a common strategy to measure any kind of variability in a signal or phenomenon. Some methods were developed to adapt information entropy measures to bird song data trying to emphasize its versatility aspect.
José R.C. Piqueira
doaj   +1 more source

Quantum simulation of Rindler transformations

open access: yes, 2018
We show how to implement a Rindler transformation of coordinates with an embedded quantum simulator. A suitable mapping allows to realise the unphysical operation in the simulated dynamics by implementing a quantum gate on an enlarged quantum system ...
Sabín, Carlos
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

RESEARCH CONCERNING THE POSITIONAL ANALYSIS OF A FOURTH CLASS MECHANISM [PDF]

open access: yesRomanian Journal of Petroleum & Gas Technology
It is well known that with the increase in the class of mechanisms, the complexity of their analysis methods also increases accordingly. This is especially the case for mechanisms of class greater than four that contain kinematic groups whose structure ...
Georgeta Toma
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

The Versatile Synapse [PDF]

open access: yesJournal of Experimental Biology, 1984
ABSTRACT‘Typically’ chemical synaptic transmission takes place when an influx of calcium ions during a presynaptic nerve impulse triggers exocytosis of neurotransmitter substance from synaptic vesicles. The neurotransmitter diffuses across the synaptic cleft and occupies receptors embedded in the subsynaptic membrane.
openaire   +2 more sources

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