Results 91 to 100 of about 2,984,261 (324)

Benign TdT-positive cells in pediatric and adult lymph nodes: a potential diagnostic pitfall [PDF]

, 2018
Benign TdT-positive cells have been documented in a variety of non-hematopoietic tissues. Scant data are however available on their presence in non-neoplastic lymph nodes.
AGOSTINELLI, CLAUDIO, Bertuzzi, Clara, BRIGNOLA, STEFANO, Pillon, Marta, Pizzi, Marco, Righi, Simona, Rugge, Massimo, Sabattini, Elena, Semenzato, Gianpietro   +8 more
core   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Chromatin establishes an immature version of neuronal protocadherin selection during the naive-to-primed conversion of pluripotent stem cells. [PDF]

, 2019
In the mammalian genome, the clustered protocadherin (cPCDH) locus provides a paradigm for stochastic gene expression with the potential to generate a unique cPCDH combination in every neuron.
Allegue, Catarina, Almenar-Queralt, Angels, Bohaciakova, Dasa, Chaves, Rodrigo S, Chen, Andrew G, Dittrich, Marcus, Driscoll, Shawn P, El Hajj, Nady, Fong, Lauren K, Garcia-Bassets, Ivan, Goldstein, Lawrence SB, Hruska-Plochan, Marian, Kim, Hong Sook, Kohlnhofer, Bridget, Ma, Qi, Mackintosh, Carlos, Marsala, Martin, Merkurjev, Daria, Navarro, Michael, Tadokoro, Takahiro, Woodruff, Grace, Young, Jessica E   +21 more
core  

Trial protocol OPPTIMUM : does progesterone prophylaxis for the prevention of preterm labour improve outcome? [PDF]

, 2012
Background Preterm birth is a global problem, with a prevalence of 8 to 12% depending on location. Several large trials and systematic reviews have shown progestogens to be effective in preventing or delaying preterm birth in selected high risk women ...
A Shennan, American College of Obstetricians and Gynecologists, Andrew Shennan, Anon, AT Northen, BAPM/RCPCH Working Group Report, D Farine, D Wolke, EB da Fonseca, EB Fonseca, H Honest, IR Edwards, Jane E Norman, JE Norman, JM Dodd, JM Dodd, John Norrie, L Sanchez-Ramos, M Arbyn, M Junpeng, March of Dimes Foundation, N Modi, Neil Marlow, Neil Sebire, PA Lachenbruch, Phillip Bennett, PJ Meis, R Romero, RL Goldenberg, RN Hoover, S Kenyon, SL Kenyon, Sonia Whyte, SS Hassan, Stavros Petrou, Stephen Robson, Steven Thornton, Tina Lavender   +37 more
core   +5 more sources

PSFHSP-Net: an efficient lightweight network for identifying pubic symphysis-fetal head standard plane from intrapartum ultrasound images

Medical and Biological Engineering and Computing
The accurate selection of the ultrasound plane for the fetal head and pubic symphysis is critical for precisely measuring the angle of progression. The traditional method depends heavily on sonographers manually selecting the imaging plane.
Ruiyu Qiu, Mengqiang Zhou, Jieyun Bai, Yaosheng Lu, Huijin Wang   +4 more
semanticscholar   +1 more source

Maternal and fetal complications associated with systemic lupus erythematosus

Medicine, 2020
Background: Recent guidelines provide better treatment and management of pregnancy in women with systemic lupus erythematosus (SLE). In this analysis, we aimed to systematically assess the maternal and fetal complications associated with SLE using the ...
Wen He, Hua Wei
semanticscholar   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Non-reassuring fetal heart rate and associated factors among laboring mothers at southern public hospitals in Ethiopia: a poisson regression model

Scientific Reports
Non-reassuring fetal heart rate is a critical indicator of fetal well-being. It is used to predict fetal hypoxia and metabolic acidosis due to insufficient fetal oxygenation and is the major contributor to perinatal mortality and morbidity.
Abeba Bishaw Asnake, Assefa Desalew, Fentahun Meseret, Haymanot Mezmur   +3 more
doaj   +1 more source

Hepatic TET3 contributes to type-2 diabetes by inducing the HNF4α fetal isoform

Nature Communications, 2020
Precise control of hepatic glucose production (HGP) is pivotal to maintain systemic glucose homeostasis. HNF4α functions to stimulate transcription of key gluconeogenic genes.
Da Li, Da Li, Tiefeng Cao, Tiefeng Cao, Xiaoli Sun, Xiaoli Sun, Sungho Jin, D. Xie, Xin-mei Huang, Xinmei Huang, Xiaoyong Yang, G. Carmichael, H. Taylor, S. Diano, Yingqun Huang   +14 more
semanticscholar   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source