Results 71 to 80 of about 212,155 (353)

RUNX2 Activation in Fibro/Adipogenic Progenitors Promotes Muscle Fibrosis in Muscular Dystrophy

Advanced Science, EarlyView.
This study revealed a novel role of the chemokine‐TGF‐β1‐RUNX2 axis in determining the fate of FAP differentiation and modulating muscle fibrosis in patients and mice with muscular dystrophies. ABSTRACT Clinical evidence indicates concurrent muscle inflammation and fibrosis in muscular dystrophies (MDs); however, the molecular mechanisms underlying ...
Pengkai Wu, Zehua Zhang, Kai Zheng, Ziqi Zhu, Yong Zhu, Abdukahar Kiram, Lei Zhao, Huihui Chen, Zhu Xu, Xihua Li, Beicheng Sun, Zhijian Li, Dengqiu Xu   +12 more
wiley   +1 more source

A new technique in the surgical treatment of Hangman′s fractures: Neurospinal Academy (NSA) technique

Journal of Craniovertebral Junction and Spine, 2013
Context: Treatment of Hangman′s fractures is still controversial. Hangman′s fractures Type II and IIA are usually treated with surgical procedures. Aim: This study aims at describing the Neurospinal Academy (NSA) technique as an attempt to achieve an ...
Sedat Dalbayrak, Onur Yaman, Mesut Yilmaz   +2 more
doaj   +1 more source

Age related diffusion and tractography changes in typically developing pediatric cervical and thoracic spinal cord [PDF]

, 2018
Background and objective: Diffusion tensor imaging (DTI) and diffusion tensor tractography (DTT) are two techniques that can measure white matter integrity of the spinal cord. Recently, DTI indices have been shown to change with age.
Alizadeh, Mahdi, Conklin, PhD, Chris, Faro, Scott H., Finsterbusch, Jürgen, Fisher, Joshua, Flanders, Adam, Krisa, PhD, Laura, Middleton, Devon, Mohamed, PhD, Feroze, Mulcahey, M. J., Saksena, PhD, Sona, Sultan, Yusra   +11 more
core   +3 more sources

Magnetically Responsive Piezoelectric Nanocapacitors Enhance Neural Recovery Following Spinal Cord Injury via Targeted Spinal Magnetic Stimulation

Advanced Science, EarlyView.
This study presents a novel “in vivo–in vitro” therapeutic strategy for spinal cord injury by leveraging magnetically responsive piezoelectric nanomaterials. These nanomaterials enable targeted delivery of localized electrical stimulation at the injury site through noninvasive external magnetic actuation, thereby promoting axonal regeneration and ...
Zhihang Xiao, Tingting Li, Lechi Zhang, Chunya Xia, Zelin Su, Xuyan Ren, Yingjie Fan, Zerui Wu, Yaobo Liu, Min Su   +9 more
wiley   +1 more source

Which anatomic structures are responsible for the reduction loss after hybrid stabilization of osteoporotic fractures of the thoracolumbar spine?

BMC Musculoskeletal Disorders, 2020
Introduction Hybrid stabilization is an accepted therapy strategy for unstable osteoporotic thoracolumbar fractures. However, a moderate reduction loss has been reported and it remains unclear which anatomic structure is responsible for the reduction ...
Ulrich J. Spiegl, Annette B. Ahrberg, Christine Anemüller, Jan-Sven Jarvers, Stefan Glasmacher, Nicolaus von der Höh, Christoph Josten, Christoph-Eckhard Heyde   +7 more
doaj   +1 more source

Subacute Presentation of Central Cord Syndrome Resulting from Vertebral Osteomyelitis and Discitis: A Case Report [PDF]

, 2020
Introduction: Central cord syndrome (CCS) is a clinical syndrome of motor weakness and sensory changes. While CCS is most often associated with traumatic events.
Cerda, Melinda, Dang, Thomas, Dong, Fanglong, Fenati, Greg, Neeki, Michael M., Rabiei, Massoud   +5 more
core  

Vertebral Body Lavage Reduces Hemodynamic Response to Vertebral Body Augmentation With PMMA [PDF]

Global Spine Journal, 2018
Study Design: Retrospective comparative study. Objectives: To assess the effect of vertebral body lavage (VBL) on (1) systemic blood pressure, (2) heart rate, and (3) oxygen saturation following cement augmentation procedures for acute vertebral compression fractures (VCFs).
Christoph E. Albers, Philipp M. Schott, Sufian S. Ahmad, Lorin M. Benneker, Nadine Nieuwkamp, Sven Hoppe   +5 more
openaire   +3 more sources

CRISPLD2 Attenuates Intervertebral Disc Degeneration by Suppressing Oxidative Stress‐Induced Ferroptosis through the miR‐548I‐IL17A Axis

Advanced Science, EarlyView.
This study identifies CRISPLD2 as a key protector against IVDD. By regulating ferroptosis through the CRISPLD2–miR‐548I–IL17A axis, CRISPLD2 maintains NPCs homeostasis and reduces oxidative stress. Restoring CRISPLD2 expression effectively alleviates disc degeneration and highlights a promising therapeutic strategy for discogenic low back pain ...
Yangyang Shi, Fudong Li, Tianyi Zhao, Kaiqiang Sun, Danying Zhang, Chen Yan, Ximing Xu, Jingchuang Sun, Xulin Hu, Xin Yong, Jiangang Shi, Yuan Wang   +11 more
wiley   +1 more source

Osteoclast‐Derived SLIT3 Mediates Osteoarthritis Pain and Degenerative Changes

Advanced Science, EarlyView.
In TMJ‐OA, osteoclasts play a significant role in promoting the growth of sensory nerves at the osteochondral interface. In early OA, TRAP+ osteoclast‐derived SLIT3 induces sensory nerve growth into the condylar cartilage. This nerve growth facilitates the development of pain associated with OA.
Weiwei Zhu, Wenpin Qin, Jialu Gao, Yihan Guo, Xiaoxiao Han, Zhangyu Ma, Xiaokang Zhang, Jie He, Jing Liu, Bo Gao, Changjun Li, Lina Niu, Jianfei Yan, Kai Jiao   +13 more
wiley   +1 more source

Thoracolumbar curve behavior after selective thoracic anterior vertebral body tethering in Lenke 1A vs Lenke 1C curve patterns [PDF]

, 2023
Michelle C. Welborn, Laurel C. Blakemore, Cameron Handford, Firoz Miyanji, Stefan Parent, Ron El‐Hawary   +5 more
openalex   +1 more source