Results 41 to 50 of about 1,074,787 (230)

Risk factors for secondary fractures to percutaneous vertebroplasty for osteoporotic vertebral compression fractures: a systematic review

open access: yesJournal of Orthopaedic Surgery and Research, 2021
Background Osteoporotic vertebral compression fracture (OVCF) is one of the most common fragile fractures, and percutaneous vertebroplasty provides considerable long-term benefits.
Wei Mao   +6 more
doaj   +1 more source

The Frequency of Spontaneous Vertebral Fracture in Geriatric Patients and the Relationship of Vertebral Fractures with Age: A Retrospective Study [PDF]

open access: yes, 2021
Objective:Vertebral fractures impair the quality of life in the geriatric patients and increase their economic costs. In this study, we aimed to identify spontaneous vertebral fracture rates and associated risk factors in the elderly.Materials and ...
Zeynep Kılıç   +3 more
core   +1 more source

Risk factors of new vertebral compression fracture after percutaneous vertebroplasty or percutaneous kyphoplasty

open access: yesFrontiers in Endocrinology, 2022
BackgroundNew vertebral compression fracture (VCF) may occur in patients who underwent percutaneous vertebroplasty (PVP) or percutaneous kyphoplasty (PKP) for osteoporotic vertebral compression fracture (OVCF). However, the risk factors of new VCF remain
Yuanpei Cheng, Xiaokang Cheng, Han Wu
doaj   +1 more source

ACSL4‐Dependent Lysosomal Lipid Peroxidation Links WTAP‐Mediated m6A Modification to Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
IL‐1β upregulates the protein level of WTAP, which promotes the m6A modification of ACSL4 mRNA in an IGF2BP2‐dependent manner, thereby enhancing its stability. The increased ACSL4 drives lipid peroxidation, leading to lysosomal membrane permeabilization (LMP) and impaired mitophagy, which collectively accelerate intervertebral disc degeneration (IVDD).
Shu Jia   +8 more
wiley   +1 more source

Logistic regression analysis for present of osteoporotic vertebral compression fracture.

open access: yes, 2019
Logistic regression analysis for present of osteoporotic vertebral compression fracture.
Myung-Hoon Han (2576842)   +4 more
core   +1 more source

Local and global microarchitecture is associated with different features of bone biomechanics

open access: yesBone Reports, 2020
Purpose: Beside areal bone mineral density (aBMD), evaluation of fragility fracture risk mostly relies on global microarchitecture. However, microarchitecture is not a uniform network.
Jean-Paul Roux   +4 more
doaj   +1 more source

Acid‐Responsive Nanobot‐Integrated Core‐Shell Microneedles Reprogram the Degenerative Annulus Fibrosus Microenvironment Through Epigenetic Suppression of Ferroptosis

open access: yesAdvanced Science, EarlyView.
An acid‐responsive core‐shell microneedle system normalizes the degenerative annulus fibrosus microenvironment by consuming pathological H+, generating O2, and providing NIR‐amplified redox buffering. Mechanistically, it epigenetically suppresses ferroptosis via DNMT3A‐dependent methylation of the ATF3 promoter, relieving ATF3‐mediated repression of ...
Lu Tan   +7 more
wiley   +1 more source

The acute osteoporotic vertebral compression fracture. Its natural course and characteristics. [PDF]

open access: yes, 2009
Aim: The overall aim of this thesis was to investigate the natural course and the characteristics of the acute osteoporotic vertebral compression fracture in order to better understand and improve treatment for this type of fracture.
Suzuki, Nobuyuki
core   +1 more source

Artificial intelligence in risk prediction and diagnosis of vertebral fractures

open access: yesScientific Reports
With the increasing prevalence of vertebral fractures, accurate diagnosis and prognostication are essential. This study assesses the effectiveness of AI in diagnosing and predicting vertebral fractures through a systematic review and meta-analysis.
Srikar R. Namireddy   +12 more
doaj   +1 more source

Persistent Zn2+ Influx‐Mediated Deacetylation of ANXA2 Regulates the “Zn2+‐Autophagic Flux” and Alleviates Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
Zinc transporter SLC39A14 sustains intracellular Zn2+ levels to activate SIRT3‑dependent ANXA2 deacetylation at K302. This modification weakens ANXA2‑mTOR binding and releases autophagic‑flux suppression in nucleus pulposus cells. Dysregulated Zn2+ homeostasis disrupts this axis to drive intervertebral disc degeneration.
Yuxin Jin   +23 more
wiley   +1 more source

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