Results 101 to 110 of about 292,339 (266)
Radioresistance arises partly from tumor cells evading cuproptosis via unknown defenses. This study reveals that the PRMT5‐VPS34 axis acts as a radiation‐activated anticuproptotic mechanism: PRMT5 methylates VPS34 at Arg174, recruiting USP10 to remove K48‐linked ubiquitination and prevent degradation.
Wei Chen +17 more
wiley +1 more source
Subversion of Atypical Mucin Traps by a Spore‐Coat Effector Blocks Cellular Immunity in Drosophila
While the entomopathogenic fungus Metarhizium robertsii can evade insect humoral immunity, its subversion of cellular defenses is still elusive. We identify Eac1 as a spore‐coat protein essential for infecting drosophilids by targeting atypical mucins (Sgf1 and Sgf2), which can entrap spores in a gel matrix and thereby facilitate hemocyte encapsulation.
Shiqin Li +7 more
wiley +1 more source
Transposable Element–Driven PIEZO Mutation Enhances Locust Flight in Plateau Hypoxia
Why transposable elements (TEs) persisted or expanded in genomes remains a mystery. Using integrated analysis of TE macro‐ and microevolution in locusts, our results showed that thousands of TE insertions promoted widespread adaptive variation. Subfamilies of candidate adaptive TEs amplified and reshaped species‐level genomic architecture.
Xuanzhao Li +8 more
wiley +1 more source
Abstract Premise Budding speciation occurs when peripheral populations adapt to local ecological conditions and “bud” off from a widespread progenitor species. Traditionally regarded as rare because of its sympatric and parapatric nature, budding speciation is largely understudied.
Eli J. Allen +3 more
wiley +1 more source
New records of extinct Icacinaceae from Paleocene rainforests of northwestern South America
Abstract Premise This study describes three new records of Icacinaceae—Punctiuga bachue gen. et sp. nov., Palaeophytocrene paramoae sp. nov., and Goweria bacatana sp. nov. from the Paleocene (Selandian–Thanetian) Bogotá Formation in Colombia—improving understanding of the distribution and evolution of this family in the Neotropics.
Laura M. Puente‐Santos +3 more
wiley +1 more source
Disparities in Influenza Control and Surveillance in Latin America and the Caribbean
To identify measures that mitigate the impact of influenza in Latin America and the Caribbean, we compared the burden and detection capacity in humans and animals after the 2009 pandemic.
Tatiana Hoyos-Cerón +3 more
doaj +1 more source
Nanodiamonds as Bioactive Platforms to Modulate Microbial, Mammalian, and Vertebrate Systems
Nanodiamonds (NDs) are biocompatible and antibacterial nanomaterials that support mammalian cell growth while inhibiting bacterial pathogens. NDs showed strong antibacterial activity, with Escherichia coli being more sensitive than Staphylococcus aureus. At 10 mg/mL, both bacteria exhibited ~8% viability.
Aaqil Rifai +6 more
wiley +1 more source
As climate change accelerates, understanding which species are most vulnerable and why they are vulnerable will be vital to inform conservation action.
Amanda A. Hyman +6 more
doaj +1 more source

