Results 131 to 140 of about 563,489 (286)

Disparities in Influenza Control and Surveillance in Latin America and the Caribbean

Viruses
To identify measures that mitigate the impact of influenza in Latin America and the Caribbean, we compared the burden and detection capacity in humans and animals after the 2009 pandemic.
Tatiana Hoyos-Cerón, Froylán Albarrán-Tamayo, Bernardo Bañuelos-Hernández, María Aurora Londoño-Avendaño   +3 more
doaj   +1 more source

Single‐Cell Mitochondrial Lineage Tracing Decodes Fate Decision and Spatial Clonal Architecture in Human Hematopoietic Organoids

Advanced Science, EarlyView.
This study repurposes mitochondrial DNA mutations as endogenous barcodes for lineage tracing in human pluripotent stem cell‐derived organoids. Integrated with transcriptomic and spatial data, it reveals NOTCH‐mediated stromal‐progenitor crosstalk orchestrates clonal dynamics and spatial zonation during early hematopoietic development, offering a non ...
Yan Xue, Junhao Su, Yiming Chao, Lu Liu, Xinyi Lin, Yang Xiang, Mun Kay Ho, Zezhuo Su, Junyi Chen, Zhuojuan Luo, Chengqi Lin, Ruibang Luo, Theo Aurich, Jianfeng Wu, Kelvin Sin Chi Cheung, Yuanhua Huang, Joshua W. K. Ho, Ryohichi Sugimura   +17 more
wiley   +1 more source

Exposure, sensitivity, or adaptive capacity? Reviewing assessments that use only two of three elements of climate change vulnerability

Conservation Science and Practice
As climate change accelerates, understanding which species are most vulnerable and why they are vulnerable will be vital to inform conservation action.
Amanda A. Hyman, Erin R. Crone, Abigail Benson, Jason Dunham, Abigail J. Lynch, Laura Thompson, Meryl C. Mims   +6 more
doaj   +1 more source

Inferring Gene Regulatory Networks From Single‐Cell RNA Sequencing Data by Dual‐Role Graph Contrastive Learning

Advanced Science, EarlyView.
RegGAIN is a novel and powerful deep learning framework for inferring gene regulatory networks (GRNs) from single‐cell RNA sequencing data. By integrating self‐supervised contrastive learning with dual‐role gene representations, it consistently outperforms existing methods in both accuracy and robustness.
Qiyuan Guan, Jiating Yu, Jieyi Pan, Fan Yuan, Jiadong Ji, Rusong Zhao, Zhi‐Ping Liu, Bingqiang Liu, Ling‐Yun Wu, Duanchen Sun   +9 more
wiley   +1 more source

Historia natural y conservación de los mutualismos planta-animal del bosque templado de Sudamérica austral Natural history and conservation of plant-animal mutualisms in the temperate forest of southern South America

Revista Chilena de Historia Natural, 2002
El bosque templado de Sudamérica austral (BTSA) se caracteriza por poseer un biota altamente endémica y una flora que exhibe una de las más altas incidencias de polinización biótica (particularmente ornitofilia) y dispersión animal (particularmente ...
MARCELO A. AIZEN, DIEGO P. VÁZQUEZ, CECILIA SMITH-RAMÍREZ   +2 more
doaj  

The effect of feeding frequency on the performance of juvenile cobia (Rachycentron canadum) [PDF]

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2023
J.H.S. Motta, A.B. Souza, M.F. Polese, L.S. Glória, F. Bosisio, P.P. Mendonça, M.V. Vidal Jr   +6 more
doaj   +1 more source

Transcription Factor Promiscuity Drives Regulatory Rewiring and Evolvability in Gene Networks in Bacteria

Advanced Science, EarlyView.
ABSTRACT This special issue marking the University of Bath's 60th anniversary offers an opportunity to reflect on nearly a decade of research into the evolution of gene regulatory networks (GRNs) from members of the lab and elsewhere. Our goal is to understand how GRNs rewire and how new transcription factor (TF) functions evolve. Using an experimental
Tiffany B. Taylor, Alan M. Rice
wiley   +1 more source

Genetic Control of Tissue Remodeling by a Non‐Coding SNP in ITGA8 Explains Carotenoid‐Based Color Polymorphism in Marine Mollusks

Advanced Science, EarlyView.
In this study, the orange‐muscle giant abalone (Haliotis gigantea) is used as a model to identify a non‐coding SNP that disrupts the interaction between ITGA8 pre‐mRNA and the splicing factor ILF2, leading to altered ITGA8 splicing. These splicing changes promote carotenoid accumulation in abalone muscle through the regulation of tissue remodeling ...
Xiaohui Wei, Wenzhu Peng, Zekun Huang, Bingye Yang, Yiyu Wu, Minzhen Han, Yi Wang, Bingling Peng, Guosheng Hu, Jiawei Hong, Guijia Liu, Linwei Nie, Yang Gan, Miaoqin Huang, Xuan Luo, Weiwei You, Wen Liu, Caihuan Ke   +17 more
wiley   +1 more source

Systematic Engineering of Proteases in Saccharopolyspora Spinosa Reveals Synergistic Enhancement of Spinosad Biosynthesis via Substrate Flux Optimization

Advanced Science, EarlyView.
ARTP mutagenesis yielded Saccharopolyspora spinosa mutant D184 with improved extracellular nitrogen utilization. An integrated workflow of protease genetic manipulation, multi‐omics, and rational synergy design pinpointed a pepP‐clpP‐htpX synergistic triangular combination.
Duo Jin, Wangqiong Chen, Danlu Yang, Qing Liu, Baolong Bai, Zirui Dai, Xirong Liu, Zirong Zhu, Jie Rang, Liqiu Xia   +9 more
wiley   +1 more source

Reprogrammable Phase‐Transition Composites for Adaptive Dynamic Shape Morphing

Advanced Science, EarlyView.
This paper reports a bio‐inspired reprogrammable phase‐transition composites that uses the stiffness change induced by reversible solid‐liquid phase transition to program and regulate the material deformation actuated by reversible liquid‐vapor phase transition, thereby achieving adaptive dynamic deformation in a controllable manner, and enabling ...
Yiding Zhong, Wei Tang, Xinyu Guo, Kecheng Qin, Pingan Zhu, Qincheng Sheng, Yonghao Wang, Huayong Yang, Jun Zou   +8 more
wiley   +1 more source