Results 41 to 50 of about 17,195 (263)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Bistable Mechanisms 3D Printing for Mechanically Programmable Vibration Control

open access: yesAdvanced Engineering Materials, EarlyView.
This work introduces a 3D‐printed bistable mechanism integrated into tuned mass dampers (TMDs) for mechanically adaptive passive vibration suppression. Through optimized geometry, the bistable design provides adaptable vibration reduction across a broad range of scenarios, achieving effective vibration mitigation without complex controls or external ...
Ali Zolfagharian   +4 more
wiley   +1 more source

Enumerating Minimal Vertex Covers and Dominating Sets with Capacity and/or Connectivity Constraints

open access: yesAlgorithms
In this paper, we consider the minimal vertex cover and minimal dominating sets with capacity and/or connectivity constraint enumeration problems. We develop polynomial-delay enumeration algorithms for these problems on bounded-degree graphs.
Yasuaki Kobayashi   +4 more
doaj   +1 more source

Simultaneously dominating all spanning trees of a graph

open access: yesElectronic Journal of Graph Theory and Applications, 2022
We investigate the problem of simultaneously dominating all spanning trees of a given graph. We prove that on 2-connected graphs, a subset of the vertices dominates all spanning trees of the graph if and only if it is a vertex cover.
Sebastian Johann   +2 more
doaj   +1 more source

Cubicity, boxicity, and vertex cover

open access: yesDiscrete Mathematics, 2009
12 ...
Chandran, LS, Das, Anita, Shah, CD
openaire   +2 more sources

Investigation of Thermo‐Chemical Processes in Commercial MgO‐C Refractory Bricks With and Without MgO‐C Recyclate at Elevated Temperatures

open access: yesAdvanced Engineering Materials, EarlyView.
This study investigates thermo‐chemical processes during high‐temperature testing of two commercial MgO‐C brick grades, one containing 47.5 wt.% MgO‐C recyclate. Using ETV, DTA/TG‐MS, XRD, and SEM/EDS/EBSD, mechanisms such as carbothermal reduction of magnesia, impurity incorporation into the secondary MgO surface layer, and calcium‐rich phase ...
Alexander Schramm   +6 more
wiley   +1 more source

Two Heuristic Algorithms for the Minimum Weighted Connected Vertex Cover Problem Under Greedy Strategy

open access: yesIEEE Access, 2022
The Minimum Weighted Connected Vertex Cover problem (MWCVC) is to find a subset $F\subset V(G)$ with minimum weight in a node-weighted graph $G$ , such that when removing the set $F$ , the inducing graph of remaining vertices holds no edges, and the ...
Qipeng Xie   +4 more
doaj   +1 more source

Influence of an Oxygen‐Free Atmosphere on Diamond‐Single‐Grain Scratching of Ti–6Al–4V

open access: yesAdvanced Engineering Materials, EarlyView.
Single‐grain scratching of Ti–6Al–4V is investigated under controlled, oxygen‐free, and ambient atmospheres using a novel experimental setup with in situ high‐speed imaging. The approach enables direct observation of chip formation and adhesion under suppressed oxidation.
Berend Denkena   +2 more
wiley   +1 more source

An Exact Algorithm for Minimum Vertex Cover Problem

open access: yesMathematics, 2019
In this paper, we propose a branch-and-bound algorithm to solve exactly the minimum vertex cover (MVC) problem. Since a tight lower bound for MVC has a significant influence on the efficiency of a branch-and-bound algorithm, we define two novel lower ...
Luzhi Wang   +3 more
doaj   +1 more source

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