Results 41 to 50 of about 299,303 (299)

Research on Vertical Ultimate Bearing Capacity of Suction Pile of Subsea Manifold

Shiyou jixie, 2020
To understand the influenced range of the soil around the suction pile under the vertical load and address the calculation problem of the vertical bearing capacity of the suction pile, theoretical formula calculation and finite element simulation are ...
Li Shuzhao, Jia Peng, Yin Feng, Liu Pu, Shi Lei, Zhang Ning, Pang Nan   +6 more
doaj  

Seismic Behaviors of Prefabricated Reinforced Concrete Shear Walls Assembled with a Cast-in-Place Vertical Joint

Buildings, 2023
The seismic performance of prefabricated reinforced concrete shear walls is a key point in the safety of the whole assembly structure under earthquake actions.
Junna Yang, Yabin Yang, Lianchao Deng, Baoshan Sun, Zhongjia Gu, Lingxin Zeng, Shunbo Zhao   +6 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Study on bearing characteristics of super-long and super-large diameter pipe piles in silt foundation of alluvial plain of Yellow River

Frontiers in Earth Science
In recent years, super-long and super-large diameter pipe piles have been gradually applied to the foundation in the Yellow River flood area. However, its bearing mechanism is not clear, especially the unclear bearing characteristics of the pile under ...
Sifeng Zhang, Zhicheng Ren, Yingguang Zhang, Wei Fan, Chao Li, Chao Liu, Yushuai Wang   +6 more
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Ultimate bearing capacity of rigid footing under eccentric vertical load

Ultimate bearing capacity of rigid footing under eccentric vertical load, 2019
In geotechnical engineering, the stability of rigid footings under eccentric vertical loads is an important issue. This is because the number of superstructure buildings has increased and the situation of structures being subjected to eccentric vertical loading is occurring more and more frequently.
Pham, Quang N, Ohtsuka, Satoru, Isobe, Koichi, Fukumoto, Yutaka, Hoshina, Takashi   +4 more
openaire   +3 more sources

FEA of SFRC three ribbed wall panel / Azrul Md Din [PDF]

, 2014
This finite element study was carried out to investigate the steel fibre reinforced concrete with three (3) ribbed wall (SFRC-3RW) panel containing reinforced wire mesh (BRC) subjected to axial and eccentric loading also its load bearing response ...
Md Din, Azrul
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Bearing capacity of the bucket spudcan foundation for offshore jack-up drilling platforms

Petroleum Exploration and Development, 2011
To compare the bearing capacities of the traditional spudcan and the bucket spudcan, the effects of different type spudcans on the rigidity of pile legs and the entire bearing capacity were analyzed in detail.
Puyang Zhang, Hongyan Ding
doaj   +1 more source