Results 71 to 80 of about 867,804 (316)

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

open access: yesMolecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban   +12 more
wiley   +1 more source

Strategic Use of CAD-CAM Interim Restoration for the Recovery of the Vertical Dimension of Occlusion in the Posterior Partially Edentulous Jaw

open access: yesApplied Sciences, 2020
Occlusal contact loss occasionally occurs following the placement of implant-supported fixed dental prostheses in the posterior region. This complication is caused by the change in the vertical dimension of occlusion after the recovery of mastication ...
Hai Yen Mai   +3 more
doaj   +1 more source

Tumor‐agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell‐free DNA fragmentomics

open access: yesMolecular Oncology, EarlyView.
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin   +10 more
wiley   +1 more source

World prices and domestic food price spikes [PDF]

open access: yes, 2013
In this paper we aim to assess the mechanics of the global food price increases experienced in the recent years, most profoundly during the 2007-2008 food price spikes.
Bakucs, Lajos Zoltán, Fertő, Imre
core  

Signatures of fractal clustering of aerosols advected under gravity

open access: yes, 2007
Aerosols under chaotic advection often approach a strange attractor. They move chaotically on this fractal set but, in the presence of gravity, they have a net vertical motion downwards.
de Moura, Alessandro P. S.   +3 more
core   +1 more source

Functional parameters of spermatozoa obtained by a new selection device

open access: yesFEBS Open Bio, EarlyView.
This study compares density gradient centrifugation and the LensHooke CA0™ device for sperm separation. DGC requires multiple steps, specialized equipment, and technical expertise. In contrast, the CA0 device offers key practical and methodological advantages, resulting in a faster, simpler, and more affordable sperm selection method.
Julio C. Chávez   +8 more
wiley   +1 more source

Comparative evaluation of vertical dimension at rest before extraction, after extraction and after rehabilitation with complete denture – A Cephalometric study

open access: yesJournal of Oral Biology and Craniofacial Research, 2013
Introduction: The determination of physiologic rest position of the mandible to the maxillae is of paramount importance in almost all fields of dentistry. The stability of vertical dimension at rest has been controversial if the rest position of mandible
Saurabh Uppal   +5 more
doaj   +1 more source

Downregulation of sST2, a decoy receptor for interleukin‐33, enhances subcutaneous tumor growth in murine pancreatic cancer cells

open access: yesFEBS Open Bio, EarlyView.
Subcutaneous implantation of murine Panc02 pancreatic cancer cells depleted of sST2, a soluble decoy receptor for the proinflammatory interleukin‐33 (IL‐33), leads to a decreased number of GLUT4‐positive cancer‐associated adipocytes, reduced levels of the anti‐inflammatory molecule adiponectin, increased phosphorylation of IκBα, elevated Cxcl3 ...
Miho Akimoto   +5 more
wiley   +1 more source

Spinal Cord Abnormalities in Early Pediatric Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Spinal cord lesions and atrophy in the cervical region are common in adult multiple sclerosis (MS) and correlate with disability. Whether similar abnormalities occur in pediatric MS patients is largely unknown. Clinical and MRI evaluations were performed in 38 pediatric MS patients and 13 healthy controls (HC).
Monica Margoni   +7 more
wiley   +1 more source

The Law of Attraction: Bilateral Search and Horizontal Heterogeneity [PDF]

open access: yes
We study a matching model with heterogeneous agents, nontransferable utility and search frictions. Agents differ along a horizontal dimension (e.g. taste) and a vertical dimension (e.g. income). Agents’ preferences coincide only in the vertical dimension.
Dirk Hofmann, Salmai Qari
core  

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