Results 111 to 120 of about 178,663 (403)

Susceptibility to Fear of Heights in Bilateral Vestibulopathy and Other Disorders of Vertigo and Balance

Frontiers in Neurology, 2018
Aims: To determine the susceptibility to visual height intolerance (vHI) in patients with acquired bilateral vestibulopathy (BVP). The question was whether postural instability in BVP, which is partially compensated for by visual substitution of the ...
Thomas Brandt, Thomas Brandt, Eva Grill, Eva Grill, Michael Strupp, Michael Strupp, Doreen Huppert, Doreen Huppert   +7 more
doaj   +1 more source

Combination vs. single‐drug nonprescription analgesics for acute pain management: A narrative review

British Journal of Clinical Pharmacology, EarlyView.
Combining nonprescription analgesics with different mechanisms of action has been proposed as a rational strategy to optimize the management of acute pain. This review assessed the efficacy and safety of nonprescription analgesics, including paracetamol (acetaminophen), metamizole and nonsteroidal anti‐inflammatory drugs (NSAIDs) used in combination vs.
Ali Mobasheri, Bart Morlion, Vidhu Sood Sethi, Mary Cardosa, Oscar Della Pasqua, Pranab Kalita   +5 more
wiley   +1 more source

Mobile Spatiotemporal Gait Segmentation Using an Ear-Worn Motion Sensor and Deep Learning

Sensors
Mobile health technologies enable continuous, quantitative assessment of mobility and gait in real-world environments, facilitating early diagnoses of gait disorders, disease progression monitoring, and prediction of adverse events like falls ...
Julian Decker, Lukas Boborzi, Roman Schniepp, Klaus Jahn, Max Wuehr   +4 more
doaj   +1 more source

Efficacy and safety of a selective partial agonist for nociception/orphanin‐FQ peptide (NOP) receptors in patients with insomnia disorder

British Journal of Clinical Pharmacology, EarlyView.
Aims Insomnia is a common sleep disorder, affecting up to 20% of the world population and adversely impacting productivity, health, and overall well‐being. Although pharmacologic options exist to treat insomnia, the health‐related quality of life for patients who are prescribed hypnotics is no higher than for those who are not, revealing a significant ...
Garth T. Whiteside, Ellie He, Manjunath S. Shet, Mingyan Zhou, Maha Ahmad, Stephen C. Harris   +5 more
wiley   +1 more source

Genome-Wide Association Study in Vestibular Neuritis: Involvement of the Host Factor for HSV-1 Replication

Frontiers in Neurology, 2018
Objective: In order to identify genetic variants associated with vestibular neuritis, a common cause of peripheral vertigo with a potential causative link to the reactivation of herpes simplex type 1 (HSV-1), we conducted a genome-wide association study ...
Dan Rujescu, Dan Rujescu, Annette M. Hartmann, Ina Giegling, Ina Giegling, Bettina Konte, Marko Herrling, Susanne Himmelein, Susanne Himmelein, Michael Strupp, Michael Strupp   +10 more
doaj   +1 more source

Deprescribing drugs with anticholinergic effects in older patients with increased risk of dementia in the multicomponent intervention study AgeWell.de

British Journal of Clinical Pharmacology, EarlyView.
Aim Drugs with anticholinergic effects are often considered as potentially inappropriate medications, especially for older patients, and deprescribing such drugs may improve cognitive function. The aim was to investigate the effectiveness of counselling on drug risks as part of a multimodal intervention to prevent cognitive decline. Methods The AgeWell.
Laura K. Lepenies, Hanna M. Seidling, Alexander Pabst, Melanie Luppa, Juliane Döhring, Martin Williamson, Thomas Frese, Jochen Gensichen, Wolfgang Hoffmann, Hanna Kaduszkiewicz, Hans‐Helmut König, Jochen René Thyrian, Birgitt Wiese, Steffi G. Riedel‐Heller, David Czock   +14 more
wiley   +1 more source

Longitudinal Results With Intratympanic Dexamethasone in the Treatment of Ménière’s Disease [PDF]

, 2008
To assess patient satisfaction with vertigo control using intratympanic (IT) dexamethasone (12 mg/mL) for medically refractory unilateral Meniere's disease. STUDY DESIGN: Retrospective study.
Boleas-Aguirre, M.S. (María Soledad), Carey, J.P. (John P.), Lin, F.R. (Frank R.), Minor, LL.B. (LLoyd B.), Santina, C.C. (Charles C.) della   +4 more
core   +1 more source

Development of latex / silica aerogel composites for thermal insulation applications

Developments in the Built Environment
Silica aerogel stands out as an exceptional thermal insulation material and is a great candidate for modern and energy-efficient buildings. However, silica aerogel also faces many challenges, mainly due to its expensive, unsustainable and difficult ...
Samuel Pantaleo, Florent Gauvin, Katrin Schollbach, H.J.H. Brouwers   +3 more
doaj   +1 more source

Effect of vepdegestrant, a PROTAC oestrogen receptor degrader, on dabigatran and rosuvastatin pharmacokinetics in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aims To evaluate the effects of vepdegestrant, a PROteolysis TArgeting Chimera (PROTAC) oestrogen receptor degrader, on the pharmacokinetics of dabigatran (a P‐glycoprotein [P‐gp] substrate) and rosuvastatin (a breast cancer resistance protein [BCRP] substrate).
Derek Z. Yang, Li Zhou, Jennifer A. Winton, Kyle T. Matschke, Constantino Kantaridis, Kristine Doyle, Kimberly C. Lee, Naihan Chen, Yuanyuan Zhang, Weiwei Tan   +9 more
wiley   +1 more source

Spontaneous intracranial hypotension : two steroid-responsive cases [PDF]

, 2018
Purpose: Spontaneous intracranial hypotension (SIH) is characterised by orthostatic headache, low cerebrospinal fluid pressure and diffuse pachymeningeal enhancement after intravenous gadolinium contrast administration.
Alexis, Zandolino, Andrea, Manto, Antonietta, Serino, Camilla, Russo, Giacomo, Fenza, Vincenzo, Buono   +5 more
core   +1 more source