Results 141 to 150 of about 144,570 (357)

Chemometric Optimization of BF3·OEt2‐Mediated Cyclization of Cannabidiol to Rare Δ⁴‐ and Iso‐THC Isomers

open access: yesChemistry – A European Journal, EarlyView.
Find the path! The present paper points out the potentialities of chemometrics tools to design selective BF3·OEt2 catalyzed procedures for the preparation of Δ⁹‐THC, Δ⁸‐THC, Δ⁸‐iso‐THC, Δ⁴‐iso‐THC, Δ⁴(⁸)‐iso‐THC, by simply tuning the initial concentration of CBD, the amount of the Lewis acid, the reaction time as well as the nature of the solvent ...
Arianna Bini   +5 more
wiley   +1 more source

VERTIGO AND VISION [PDF]

open access: green, 1917
Percy Fridenberg
openalex   +1 more source

Clinical and neurophysiological changes in patients with pineal region expansions [Kliničke i neurofiziološke značajke u bolesnika s ekspanzivnim tvorbama pinealne regije] [PDF]

open access: yes, 2013
In the last 20 years neurological and neurosurgical follow up of our patients with pineal region expansions (118 patients) pointed to certain clinical and neurophysiological regularities.
Hajnšek, Sanja   +5 more
core  

Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Food Effect of Bexicaserin in Healthy Participants: A First‐in‐Human Randomized, Double‐Blind, Placebo‐Controlled Single Ascending Dose Escalation Phase 1 Study

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract Bexicaserin (LP352) is a selective 5‐hydroxytryptamine 2C (5‐HT2C) superagonist in development for the treatment of seizures in developmental and epileptic encephalopathies (DEEs). This double‐blind, placebo‐controlled, single ascending dose (SAD) Phase 1 study aimed to assess the safety, tolerability, and pharmacokinetic (PK) and ...
Rosa Chan   +6 more
wiley   +1 more source

Migraine and vertigo

open access: yes, 1991
Migraine is an episodic disorder that has headache as its most prominent feature and occurs in various combinations with autonomic, gastrointestinal and neurological symptoms. Current estimates indicate that 23 million Americans suffer from migraine headaches with more than 11 million experiencing significant headache-related disability (Stewart et al.
openaire   +2 more sources

Balance ninja: towards the design of digital vertigo games via galvanic vestibular stimulation [PDF]

open access: yes, 2016
Vertigo – the momentary disruption of the stability of perception – is an intriguing game element that underlies many unique play experiences, such as spinning in circles as children to rock climbing as adults, yet vertigo is relatively unexplored when ...
Byrne, Richard   +2 more
core  

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Ascending Doses and Dose Titration of Bexicaserin in Healthy Participants in a Randomized, Double‐Blind, Placebo‐Controlled Study

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract Bexicaserin (LP352) is a selective superagonist of the 5‐hydroxytryptamine 2C (5‐HT2C) receptor currently in development for the treatment of seizures that arise from developmental and epileptic encephalopathies. This phase 1, double‐blind, placebo‐controlled multiple ascending dose (MAD) study assessed the safety, tolerability, and ...
Jonathan Williams   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy