Results 201 to 210 of about 144,570 (357)

A Phase 1 Randomized Study: Garadacimab Pharmacokinetics, Safety, and Tolerability After Administration via Autoinjector/Pre‐Filled Pen Versus Pre‐Filled Syringe in Healthy Participants

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Garadacimab is a novel, fully human, anti‐activated factor XII monoclonal antibody approved for long‐term prophylaxis of patients with hereditary angioedema. This open‐label, parallel‐group, Phase 1, single‐center, bridging study in healthy adults (18–55 years of age) characterized the pharmacokinetics and safety of a single 200 mg ...
Fiona Glassman   +9 more
wiley   +1 more source

An ataxia test battery not requiring the use of rails [PDF]

open access: yes
Ataxia on normal humans and those with vestibular defects and ...
Fregly, A. R., Graybiel, A.
core   +1 more source

In Vitro and Clinical Evaluation of Potential Interactions of Bemnifosbuvir with Drug Transporters

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Bemnifosbuvir is a novel oral guanosine nucleotide prodrug candidate for the treatment of chronic hepatitis C virus infection. Potential drug–drug interactions (DDIs) of bemnifosbuvir as a substrate or perpetrator with regard to ATP‐binding cassette (ABC) and solute carrier (SLC) transporters were evaluated in vitro and in clinical studies ...
Xiao‐Jian Zhou   +9 more
wiley   +1 more source

Exogenous Melatonin and Sleep Quality: A Scoping Review of Systematic Reviews

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Melatonin is increasingly used to treat sleep disturbances, yet its overall efficacy remains unclear due to variability in existing evidence. This scoping review aimed to synthesize systematic reviews with meta‐analyses assessing the effects of exogenously administered melatonin on sleep quality in humans.
Samyuktha Iyer   +3 more
wiley   +1 more source

Association Between Gut-Brain Axis Dysfunction and Vestibular Migraine Severity. [PDF]

open access: yesCureus
Masood MA   +9 more
europepmc   +1 more source

External carotid steal and lateral medullary infarction - is there a pathogenetic connection? [PDF]

open access: yes, 1983
A Wallenberg   +18 more
core   +1 more source

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