Results 51 to 60 of about 117,562 (243)

Medical students' initial experiences of the dissection room and interaction with body donors: A qualitative study of professional identity formation, educational benefits, and the experience of Pasifika students

Anatomical Sciences Education, EarlyView.
Abstract The first experience of medical students in the dissecting room (DR) likely influences professional identity formation (PIF). Sparse data exist exploring how exposure to the DR and body donors without undertaking dissection influences PIF, or how culture may influence this experience.
Jacob Madgwick, Lynley Anderson, Jon Cornwall   +2 more
wiley   +1 more source

Otolaryngologic symptoms in multiple sclerosis: a review [PDF]

, 2018
Many symptoms of multiple sclerosis may affect the ear, nose and throat. The most common otolaryngologic symptoms of multiple sclerosis are speech disorders, followed by sleep disorders, vertigo and disequilibrium, dysphagia, smell alterations, and ...
BALLA, MARIA PAOLA, DE VINCENTIIS, Marco, DI STADIO, Arianna, GRECO, Antonio, ORLANDO, Maria Patrizia, RALLI, MASSIMO, RUSSO, FRANCESCA YOSHIE, VISCONTI, IRENE CLAUDIA   +7 more
core   +1 more source

First‐in‐human safety, tolerability, pharmacokinetics and pilot food‐effect study of the candidate antimalarial compound MMV367

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim To evaluate the safety, tolerability and pharmacokinetics in healthy participants of orally administered MMV367 (GSK3772701), a novel antimalarial interfering with Plasmodium falciparum acyl coenzyme A synthetase 10/11 function. Methods This first‐in‐human study enrolled 47 healthy male and female participants.
Andrea Kuemmerle, Nand Singh, Denis Gossen, Annick Janin, Raman Sharma, Anthony Cahn, Rachel A. Gibson, Somasekhara R. Menakuru, Erin Lambourne, Tom Dove, Francisco‐Javier Gamo, Laura Sanz, Benoit Bestgen, Stephan Chalon   +13 more
wiley   +1 more source

Hubungan Antara Vertigo Dengan Riwayat Jatuh Pada Lanjut Usia Di Kota Surakarta [PDF]

, 2015
Background: Vertigo is not a disease but a symptom of a disease. Vertigo causes by the disturbance in the Vestibular system. In the elderly people’s case, the decrease of the vestibular system can cause balance disturbance. It happens because the changes
, Umi Budi Rahayu, SSt. Ft. SPd. M. Kes, , Yulisna Mutia Sari, SSt.FT., M.Sc (GRS, FAUZIAH, Enny   +2 more
core  

Adverse events associated with monoclonal antibodies used for treatment of COVID‐19: A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, Volume 91, Issue 5, Page 1306-1321, May 2025.
Aims This review aimed to synthesise the evidence related to the incidence of serious and non‐serious adverse events with the use of monoclonal antibodies (mAbs) among COVID‐19 patients. Methods Databases were searched from January 2020 to September 2023 for randomized clinical trials (RCTs) that used mAbs for the treatment of COVID‐19 regardless of ...
Htet Htet, Han You Kyung, Ismail Abdul Sattar Burud, Heethal Jaiprakash, Thiruselvi Subramaniam, Igor Iezhitsa, Renu Agarwal   +6 more
wiley   +1 more source

HSV-1 not only in human vestibular ganglia but also in the vestibular labyrinth [PDF]

, 2001
Reactivation of herpes simplex virus type 1 (HSV-1) in the vestibular ganglion (VG) is the suspected cause of vestibular neuritis (VN). Recent studies reported the presence of HSV-1 DNA not only in human VGs but also in vestibular nuclei, a finding that ...
Arbusow, Viktor, Brandt, Thomas, Mascolo, Andrea, Strupp, Michael, Theil, Diethilde   +4 more
core   +1 more source

Pharmacology and safety of TAS5315, a Bruton tyrosine kinase inhibitor, in healthy volunteers: First‐in‐human, randomized, ascending‐dose studies

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim TAS5315 is a Bruton tyrosine kinase (Btk) inhibitor in development for autoimmune and allergic diseases, including rheumatoid arthritis (RA) and chronic spontaneous urticaria (CSU). Two clinical studies evaluated the pharmacology and safety of single and multiple oral doses of TAS5315.
Yuji Kumagai, Tomoe Fujita, Mika Maeda, Akiko Yamamoto, Hideki Amano   +4 more
wiley   +1 more source

Evaluating the effectiveness of virtual laboratory simulations for graduate‐level training in genetic methodologies

Biochemistry and Molecular Biology Education, EarlyView.
Abstract Virtual Labs (vLabs) have been gaining popularity in high school and undergraduate education, but there are few studies looking at their use in graduate‐level courses. In this study, we investigated the use of six Labster vLabs assigned as homework in a graduate‐level in‐person Genomic Methodologies course at the University of Toronto.
Johanna S. Carroll, Hedieh Najafi, Martina Steiner   +2 more
wiley   +1 more source

Subtotal petrosectomy and cerebrospinal fluid leakage in unilateral anacusis [PDF]

, 2014
Objective This study presents a group of patients experiencing recurrent cerebrospinal fluid (CSF) leakage associated with ipsilateral anacusis who underwent subtotal petrosectomies with the goal of stopping the CSF leak and preventing meningitis ...
Iannella, Giannicola, Magliulo, Giuseppe
core   +1 more source

An open‐label, single‐arm, multicenter, phase II trial of bireociclib as monotherapy for heavily pretreated HR‐positive, HER2‐negative advanced breast cancer patients: BRIGHT‐1 trial

Cancer Communications, EarlyView.
Abstract Background Bireociclib (XZP‐3287) is a novel selective cyclin‐dependent kinase 4 and 6 (CDK4/6) inhibitor, with a favorable safety profile demonstrated in preclinical and phase I studies. BRIGHT‐1 aimed to further explore the efficacy and safety of bireociclib monotherapy in patients with locally advanced, recurrent or metastatic, hormone ...
Jiayu Wang, Qingyuan Zhang, Tao Sun, Huiping Li, Ying Cheng, Zhongsheng Tong, Huihui Li, Wei Li, Jingfen Wang, Yuee Teng, Xinhong Wu, Jing Cheng, Zhendong Chen, Zhengqiu Zhu, Li Wang, Mingming Liu, Xianghui Duan, Lingmei Xu, Binghe Xu   +18 more
wiley   +1 more source