Results 81 to 90 of about 176,771 (387)

Dopamine D1 Receptor Contributes to Glucocorticoid‐Associated Osteonecrosis of Femoral Head Protection Through the ATF3/CHOP Axis to Inhibit Osteoblastic Apoptosis

open access: yesAdvanced Science, EarlyView.
This work identifies a novel mechanism by which dopamine D1 receptor (DRD1) contributes to the pathogenesis of glucocorticoid (GC)‐associated osteonecrosis of the femoral head (ONFH) through the regulation of osteoblastic apoptosis, indicating that DRD1 serves as a critical mediator of the crosstalk between the nervous and skeletal systems.
Kai Zheng   +11 more
wiley   +1 more source

Perceived Vertical and Lateropulsion: Clinical Syndromes, Localization, and Prognosis [PDF]

open access: yes, 2000
We present a clinical classification of central vestibular syndromes according to the three major planes of action of the vestibulo-ocular reflex: yaw, roll, and pitch.
Brandt   +3 more
core   +1 more source

Adiponectin Assists Thrombopoietic Agents in ITP Treatment by Enhancing Myosin‐9/Rab6A‐Mediated Trafficking of c‐Mpl in MKs

open access: yesAdvanced Science, EarlyView.
This study revealed that adiponectin facilitates the therapeutic efficiency of thrombopoietic agents by stimulating the membrane trafficking of c‐Mpl in MKs, which provides a point for ITP therapy. Moreover, a novel c‐Mpl trafficking mechanism based on the Myosin‐9/Rab6A complex is constructed. These findings provide new insights into the applicability
Xin Zhao   +8 more
wiley   +1 more source

BPPV: Comparison of the SémontPLUS With the Sémont Maneuver: A Prospective Randomized Trial

open access: yesFrontiers in Neurology, 2021
Objective: To compare the efficacy of the Sémont maneuver (SM) with the new “SémontPLUS maneuver” (SM+) in patients with posterior canal BPPV canalolithiasis (pcBPPVcan).Methods and Patients: In a prospective trinational (Germany, Italy, and Belgium ...
Michael Strupp   +9 more
doaj   +1 more source

The ‘Trombone Shot’: From San Francisco to Middle Earth via Amity. [PDF]

open access: yes, 2009
Jaws may have popularised the shot, but it was cameraman Irwin Roberts working on Alfred Hitchcock’s Vertigo who would introduce audiences to the conta-zoom, and with it bring drama and suspense hurtling toward us like never ...
Berger, Richard
core  

Superior Semicircular Canal Dehiscence in a Patient with Ehlers-Danlos Syndrome: A Case Report. [PDF]

open access: yes, 2017
Superior semicircular canal dehiscence (SSCD) is a bony defect in the middle cranial fossa floor that results in an abnormal connection between the inner ear and cranial vault.
Chung, Lawrance K   +4 more
core   +1 more source

Oxytocin Reduces Subjective Fear in Naturalistic Social Contexts via Enhancing Top‐Down Middle Cingulate Amygdala Regulation and Brain‐Wide Fear Representations

open access: yesAdvanced Science, EarlyView.
This double‐blind, placebo‐controlled study demonstrates that intranasal oxytocin reduces subjective fear in immersive, naturalistic social (but not non‐social) contexts. Concomitant fMRI reveals that oxytocin enhances middle cingulate activity and amygdala connectivity while it modulates network‐level connectivity and attenuates reactivity of a brain ...
Kun Fu   +17 more
wiley   +1 more source

Posterior Semicircular Canal Plugging Relieves Tumarkin’s Crisis in Ménière’s Disease Patients

open access: yesAudiology Research
(1) Background: Patients affected by Ménière’s disease can experience Tumarkin’s syndrome, which is characterized by postural instability, gait abnormalities, and, occasionally, an abrupt loss of balance known as vestibular drop attack or Tumarkin’s ...
Francesco Comacchio   +6 more
doaj   +1 more source

Effectiveness of a training intervention to improve the management of vertigo in primary care: a multicentre cluster-randomised trial, VERTAP

open access: yesTrials, 2022
Background Benign paroxysmal positional vertigo (BPPV) is the most common type of vertigo. While BPPV is best treated with canalicular repositioning manoeuvres, they are not routinely performed in primary care (PC).
Jenniffer Elizabeth Pérez Patiño   +12 more
doaj   +1 more source

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