Results 51 to 60 of about 322,223 (300)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Very-High-Cycle Fatigue Behaviors for Bearing Steel Microstructural Transformation

Crystals
It has been reported that the multiphase structure with martensite and a mixed structure obtained by the quenching and tempering of bearing steel shows high strength and ductility.
Seung-Hoon Nahm, Sang-Koo Jeon, Dong-Kyun Kim, Min-Soo Suh, Chang-Min Suh   +4 more
doaj   +1 more source

Very High Cycle Fatigue Behavior of Carbon Manganese Steels [PDF]

Advanced Materials Research, 2010
An ultrasonic fatigue testing system capable of operating at temperatures at 250 has been introduce to study the fatigue behavior of carbon manganese steels (A42 and A48) and loading frequency of approximately 20 kHz. Endurance limit results were comparable to those generated at room temperature to determine the effect of temperature. Scanning electron
Hongqian, Xue, Wagner, Danièle
openaire   +2 more sources

On the simulation of cohesive fatigue effects in grain boundaries of a piezoelectric mesostructure [PDF]

, 2008
Ferroelectric materials offer a variety of new applications in the field of smart structures and intelligent systems. Accordingly, the modelling of these materials constitutes an active field of research.
Utzinger, J., Steinmann, P., Menzel, A.
core   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Effect of Artificial Defects on the Very High Cycle Fatigue Behavior of 316L Stainless Steel

Metals, 2019
Widely used for structural materials in nuclear engineering, 316L austenitic stainless steel undergoes very high cycle fatigue (VHCF) throughout its service life.
Zhihong Xiong, Takashi Naoe, Masatoshi Futakawa   +2 more
doaj   +1 more source

Deformation mechanisms in a TiNi shape memory alloy during cyclic loading [PDF]

, 2012
The deformation mechanisms governing the cyclic stress-strain behaviour of a TiNi shape memory alloy were investigated in this work. To understand the development of these mechanisms during cyclic loading, three low-cycle fatigue tests were performed and
Billota, Giovambattista, Gerland, Michel, Gloanec, Anne-Lise   +2 more
core   +3 more sources

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

Very High Cycle Fatigue Damage of TC21 Titanium Alloy under High/Low Two-Step Stress Loading

Crystals, 2023
Very high cycle fatigue (VHCF) tests were carried out under variable amplitude loading for TC21 titanium alloy. The first level of high amplitude loading was set as 950 MPa close to yield strength, and the second level of low amplitude loading was ...
Baohua Nie, Shuai Liu, Yue Wu, Yu Song, Haiying Qi, Binqing Shi, Zihua Zhao, Dongchu Chen   +7 more
doaj   +1 more source

Size-effect in Very High Cycle Fatigue: A review

International Journal of Fatigue, 2021
Abstract It is well-known that fatigue failures in VHCF originate from defects present within the risk-volume. Moreover, experimental results have shown that the larger the specimen size and the risk-volume, the shorter is the VHCF life. This is known as size-effect and is generally due to the statistical increment of the defect size with the ...
Tridello A., Boursier Niutta C., Berto F., Paolino D. S.   +3 more
openaire   +2 more sources