Results 31 to 40 of about 72,684 (256)

Crack growth behaviour of aluminium wrought alloys in the Very High Cycle Fatigue regime [PDF]

MATEC Web of Conferences, 2018
Investigations have shown that in the regime of Very High Cycle Fatigue (VHCF) “natural” crack initiation often takes place underneath the material surface leading to crack propagation without contact to atmospheric components.
Bülbül Fatih, Kirsten Tina, Wicke Marcel, Zimmermann Martina, Brückner-Foit Angelika, Christ Hans-Jürgen   +5 more
doaj   +2 more sources

Very High Cycle Fatigue (VHCF) of notched specimens: a review

Fracture and Structural Integrity
A large number of mechanical components are subjected to fatigue loading beyond 106 cycles. The VHCF behaviour of smooth specimens has been extensively investigated in the recent years, even if more efforts are necessary to reveal the mecahnism ...
Paolo Zuliani, Carlo Boursier Niutta, Davide Salvatore Paolino, Filippo Berto, Andrea Tridello   +4 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Effect of low cycle fatigue pre-damage on very high cycle fatigue

Theoretical and Applied Mechanics Letters, 2012
AbstractCarbon-manganese steel is often applied in components of pipes in nuclear plant. Ultrasonic fatigue tests following low cycle fatigue (LCF) cycles damaged are used to study the strength of very high cycle fatigure (VHCF). The comparison of test results of simple VHCF and cumulative fatigue (LCF plus VHCF) shows that LCF load influences the ...
Huang, Zhiyong, Wang, Qingyuan, Wagner, Danièle, Bathias, Claude   +3 more
openaire   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Very-High-Cycle Fatigue Behaviors for Bearing Steel Microstructural Transformation

Crystals
It has been reported that the multiphase structure with martensite and a mixed structure obtained by the quenching and tempering of bearing steel shows high strength and ductility.
Seung-Hoon Nahm, Sang-Koo Jeon, Dong-Kyun Kim, Min-Soo Suh, Chang-Min Suh   +4 more
doaj   +1 more source

Effect of Artificial Defects on the Very High Cycle Fatigue Behavior of 316L Stainless Steel

Metals, 2019
Widely used for structural materials in nuclear engineering, 316L austenitic stainless steel undergoes very high cycle fatigue (VHCF) throughout its service life.
Zhihong Xiong, Takashi Naoe, Masatoshi Futakawa   +2 more
doaj   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

Very High Cycle Fatigue Damage of TC21 Titanium Alloy under High/Low Two-Step Stress Loading

Crystals, 2023
Very high cycle fatigue (VHCF) tests were carried out under variable amplitude loading for TC21 titanium alloy. The first level of high amplitude loading was set as 950 MPa close to yield strength, and the second level of low amplitude loading was ...
Baohua Nie, Shuai Liu, Yue Wu, Yu Song, Haiying Qi, Binqing Shi, Zihua Zhao, Dongchu Chen   +7 more
doaj   +1 more source